Literature DB >> 27993778

LEAP: constructing gene co-expression networks for single-cell RNA-sequencing data using pseudotime ordering.

Alicia T Specht, Jun Li.   

Abstract

Summary: To construct gene co-expression networks based on single-cell RNA-Sequencing data, we present an algorithm called LEAP, which utilizes the estimated pseudotime of the cells to find gene co-expression that involves time delay. Availability and Implementation: R package LEAP available on CRAN. Contact: jun.li@nd.edu. Supplementary information: Supplementary data are available at Bioinformatics online.
© The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com

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Year:  2017        PMID： 27993778      PMCID： PMC5860270          DOI： 10.1093/bioinformatics/btw729

Source DB:  PubMed          Journal:  Bioinformatics        ISSN： 1367-4803            Impact factor:   6.937


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