Literature DB >> 27987157

Incorporating Pharmacogenomics into Health Information Technology, Electronic Health Record and Decision Support System: An Overview.

Abdullah Alanazi1.   

Abstract

As the adoption of information technology in healthcare is rising, the potentiality of moving Pharmacogenomics from benchside to bedside is aggravated. This paper reviews the current status of Pharmacogenomics (PGx) information and the attempts for incorporating them into the Electronic Health Record (EHR) system through Decision Support Systems (DSSs). Rigorous review strategies of PGx information and providing context-relevant recommendations in form of action plan- dose adjustment, lab tests rather than just information- would be ideal for making clinical recommendations out of PGx information. Lastly, realistic projections of what pharmacogenomics can provide is another important aspect in incorporating Pharmacogenomics into health information technology.

Entities:  

Keywords:  Adverse drug reaction; Clinic recommendations; Decision Support Systems (DSSs); Electronic Health Record (EHR); Pharmacogenomics

Mesh：

Year:  2016        PMID： 27987157     DOI： 10.1007/s10916-016-0673-4

Source DB:  PubMed          Journal:  J Med Syst        ISSN： 0148-5598            Impact factor:   4.460


  31 in total

1.  Molecular structure of nucleic acids; a structure for deoxyribose nucleic acid.

Authors:  J D WATSON; F H CRICK
Journal:  Nature       Date:  1953-04-25       Impact factor: 49.962

Review 2.  Meaningful use of pharmacogenomics in health records: semantics should be made explicit.

Authors:  Amnon Shabo Shvo
Journal:  Pharmacogenomics       Date:  2010-01       Impact factor: 2.533

3.  Pharmacogenetic application in drug development and clinical trials.

Authors:  M M Shi; M R Bleavins; F A de la Iglesia
Journal:  Drug Metab Dispos       Date:  2001-04       Impact factor: 3.922

Review 4.  Pharmacogenomics knowledge for personalized medicine.

Authors:  M Whirl-Carrillo; E M McDonagh; J M Hebert; L Gong; K Sangkuhl; C F Thorn; R B Altman; T E Klein
Journal:  Clin Pharmacol Ther       Date:  2012-10       Impact factor: 6.875

5.  Validation and comparison of pharmacogenetics-based warfarin dosing algorithms for application of pharmacogenetic testing.

Authors:  Nitin Roper; Barry Storer; Robert Bona; Min Fang
Journal:  J Mol Diagn       Date:  2010-03-12       Impact factor: 5.568

6.  Technical desiderata for the integration of genomic data into Electronic Health Records.

Authors:  Daniel R Masys; Gail P Jarvik; Neil F Abernethy; Nicholas R Anderson; George J Papanicolaou; Dina N Paltoo; Mark A Hoffman; Isaac S Kohane; Howard P Levy
Journal:  J Biomed Inform       Date:  2011-12-27       Impact factor: 6.317

Review 7.  Pharmacogenetics, pharmacogenomics, and individualized medicine.

Authors:  Qiang Ma; Anthony Y H Lu
Journal:  Pharmacol Rev       Date:  2011-03-24       Impact factor: 25.468

Review 8.  The 1200 patients project: creating a new medical model system for clinical implementation of pharmacogenomics.

Authors:  P H O'Donnell; A Bush; J Spitz; K Danahey; D Saner; S Das; N J Cox; M J Ratain
Journal:  Clin Pharmacol Ther       Date:  2012-08-29       Impact factor: 6.875

9.  Electronic health record design and implementation for pharmacogenomics: a local perspective.

Authors:  Josh F Peterson; Erica Bowton; Julie R Field; Marc Beller; Jennifer Mitchell; Jonathan Schildcrout; William Gregg; Kevin Johnson; Jim N Jirjis; Dan M Roden; Jill M Pulley; Josh C Denny
Journal:  Genet Med       Date:  2013-09-05       Impact factor: 8.822

10.  Feasibility of incorporating genomic knowledge into electronic medical records for pharmacogenomic clinical decision support.

Authors:  Casey Lynnette Overby; Peter Tarczy-Hornoch; James I Hoath; Ira J Kalet; David L Veenstra
Journal:  BMC Bioinformatics       Date:  2010-10-28       Impact factor: 3.169
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  3 in total

1.  Integrating pharmacogenetic testing into primary care.

Authors:  Susanne B Haga
Journal:  Expert Rev Precis Med Drug Dev       Date:  2017-11-03

Review 2.  The role of medical data in efficient patient care delivery: a review.

Authors:  Kasaw Adane; Mucheye Gizachew; Semalegne Kendie
Journal:  Risk Manag Healthc Policy       Date:  2019-04-24

3.  A collaborative translational research framework for evaluating and implementing the appropriate use of human genome sequencing to improve health.

Authors:  Muin J Khoury; W Gregory Feero; David A Chambers; Lawrence C Brody; Nazneen Aziz; Robert C Green; A Cecile J W Janssens; Michael F Murray; Laura Lyman Rodriguez; Joni L Rutter; Sheri D Schully; Deborah M Winn; George A Mensah
Journal:  PLoS Med       Date:  2018-08-02       Impact factor: 11.069
  3 in total

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