Literature DB >> 2798125

alpha-DNA X: alpha and beta tetrathymidilates covalently linked to oxazolopyridocarbazolium (OPC): comparative stabilization of oligo beta-[dT]:oligo beta-[dA] and oligo alpha-[dT]:oligo beta-[dA] duplexes by the intercalating agent.

D Bazile1, C Gautier, B Rayner, J L Imbach, C Paoletti, J Paoletti.   

Abstract

The influence of the intercalating oxazolopyridocarbazolium (HOPC) on the stabilization of modified oligonucleotides: alpha-T4c5OPC or beta-T4c5OPC associated to beta-oligo (dA) was studied. It appears that the situation is different from what has been observed for the interaction of these modified oligonucleotides with poly (rA). The higher free energy of formation of the alpha-T4c5OPC :beta-oligo(dA), when compared to beta-T4c5OPC, is essentially due to the overall stability added to this system by the intercalator. This enhanced stability comes from a higher number of binding sites of HOPC for the alpha:beta duplex together with a lower van't Hoff energy of formation of the alpha:beta duplex.

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Year:  1989        PMID： 2798125      PMCID： PMC334882          DOI： 10.1093/nar/17.19.7749

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  33 in total

Review 1.  Nucleoside phosphorothioates.

Authors:  F Eckstein
Journal:  Annu Rev Biochem       Date:  1985       Impact factor: 23.643

2.  Constitutive and conditional suppression of exogenous and endogenous genes by anti-sense RNA.

Authors:  J G Izant; H Weintraub
Journal:  Science       Date:  1985-07-26       Impact factor: 47.728

3.  Calculating thermodynamic data for transitions of any molecularity from equilibrium melting curves.

Authors:  L A Marky; K J Breslauer
Journal:  Biopolymers       Date:  1987-09       Impact factor: 2.505

4.  alpha-DNA. VII. Solid phase synthesis of alpha-anomeric oligodeoxyribonucleotides.

Authors:  F Morvan; B Rayner; J P Leonetti; J L Imbach
Journal:  Nucleic Acids Res       Date:  1988-02-11       Impact factor: 16.971

5.  Anti-mRNA: specific inhibition of translation of single mRNA molecules.

Authors:  S Pestka; B L Daugherty; V Jung; K Hotta; R K Pestka
Journal:  Proc Natl Acad Sci U S A       Date:  1984-12       Impact factor: 11.205

6.  Enzymatic amplification of translation inhibition of rabbit beta-globin mRNA mediated by anti-messenger oligodeoxynucleotides covalently linked to intercalating agents.

Authors:  C Cazenave; N Loreau; N T Thuong; J J Toulmé; C Hélène
Journal:  Nucleic Acids Res       Date:  1987-06-25       Impact factor: 16.971

7.  Alpha-DNA. IV: Alpha-anomeric and beta-anomeric tetrathymidylates covalently linked to intercalating oxazolopyridocarbazole. Synthesis, physicochemical properties and poly (rA) binding.

Authors:  C Gautier; F Morvan; B Rayner; T Huynh-Dinh; J Igolen; J L Imbach; C Paoletti; J Paoletti
Journal:  Nucleic Acids Res       Date:  1987-08-25       Impact factor: 16.971

8.  Accessibility to bacterial nucleic acids of the intercalating drug aliphatic amino acid ellipticinium derivatives in Escherichia coli and Salmonella typhimurium.

Authors:  H Banoun; M Le Bret; C Auclair
Journal:  Biochemistry       Date:  1985-01-29       Impact factor: 3.162

9.  Selective inhibition of the cytopathic effect of type A influenza viruses by oligodeoxynucleotides covalently linked to an intercalating agent.

Authors:  A Zerial; N T Thuong; C Hélène
Journal:  Nucleic Acids Res       Date:  1987-12-10       Impact factor: 16.971

10.  Oligodeoxynucleotides covalently linked to intercalating agents: a new class of gene regulatory substances.

Authors:  C Hélène; T Montenay-Garestier; T Saison; M Takasugi; J J Toulmé; U Asseline; G Lancelot; J C Maurizot; F Toulmé; N T Thuong
Journal:  Biochimie       Date:  1985 Jul-Aug       Impact factor: 4.079
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  2 in total

1.  Oligonucleotides conjugated with acridine: a new type of fluorescence probes for DNA hybridization assay.

Authors:  M D Pinskaya; M E Volkov; E A Romanova; E M Volkov; J F Mouscadet; M B Gottikh
Journal:  Dokl Biochem Biophys       Date:  2004 Jan-Feb       Impact factor: 0.788

2.  Hybridization and dissociation rates of phosphodiester or modified oligodeoxynucleotides with RNA at near-physiological conditions.

Authors:  S Young; R W Wagner
Journal:  Nucleic Acids Res       Date:  1991-05-11       Impact factor: 16.971
  2 in total

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