K Klebermass-Schrehof1, S Aumüller1, K Goeral1, K Vergesslich-Rothschild2, R Fuiko1, S Brandstetter1, A Berger1, B Jilma3, N Haiden1. 1. Department of Pediatrics and Adolescent Medicine, Division of Neonatology, Intensive Care and Neuropediatrics, Medical University of Vienna, Vienna, Austria. 2. Department of General Radiology and Pediatric Radiology, Medical University of Vienna, Vienna, Austria. 3. Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria.
Abstract
OBJECTIVE: Several studies have shown a relation between the size of corpus callosum (CC) and outcome in preterm infants. Three-dimensional ultrasound (3D-US) offers new perspectives in cerebral imaging. To establish reference values for biometry of the CC in very low birth weight infants and to correlate these measurements to neurodevelopmental outcome at 5 years of age. STUDY DESIGN: Forty-three preterm infants with a gestational age <32 weeks were included. Transfontanellar 3D-US measurements were obtained at nine different timepoints. RESULTS: 3D-US-based reference values for size, length, circumference and surface area of the CC could be established. Measurements at term-equivalent age showed a correlation to neurodevelopment outcome. CONCLUSION: Reliable biometric data of the CC can be established in preterm infants by 3D-US and correlate with neurodevelopmental outcome.
OBJECTIVE: Several studies have shown a relation between the size of corpus callosum (CC) and outcome in preterm infants. Three-dimensional ultrasound (3D-US) offers new perspectives in cerebral imaging. To establish reference values for biometry of the CC in very low birth weight infants and to correlate these measurements to neurodevelopmental outcome at 5 years of age. STUDY DESIGN: Forty-three preterm infants with a gestational age <32 weeks were included. Transfontanellar 3D-US measurements were obtained at nine different timepoints. RESULTS: 3D-US-based reference values for size, length, circumference and surface area of the CC could be established. Measurements at term-equivalent age showed a correlation to neurodevelopment outcome. CONCLUSION: Reliable biometric data of the CC can be established in preterm infants by 3D-US and correlate with neurodevelopmental outcome.
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