A Stensgaard1, C Bindslev-Jensen1, D Nielsen2, M Munch3, A DunnGalvin4. 1. Odense Research Center for Anaphylaxis (ORCA), Department of Dermatology and Allergy Center, Odense University Hospital, Odense, Denmark. 2. Migrant Health Clinic, Odense University Hospital, Odense, Denmark. 3. Research Unit of General Practice, Department of Public Health, University of Southern Denmark, Odense, Denmark. 4. School of Applied Psychology, University College Cork, Cork, Ireland.
Abstract
BACKGROUND: Studies of children with food allergy typically only include the mother and have not investigated the relationship between the amount of allergen needed to elicit a clinical reaction (threshold) and health-related quality of life (HRQL). Our aims were (i) to compare self-reported and parent-reported HRQL in different age groups, (ii) to evaluate the impact of severity of allergic reaction and threshold on HRQL, and (iii) to investigate factors associated with patient-reported and parent-reported HRQL. METHODS: Age-appropriate Food Allergy Quality of Life Questionnaires (FAQLQ) were completed by 73 children, 49 adolescents and 29 adults with peanut, hazelnut or egg allergy. Parents (197 mothers, 120 fathers) assessed their child's HRQL using the FAQLQ-Parent form. Clinical data and threshold values were obtained from a hospital database. Significant factors for HRQL were investigated using univariate and multivariate regression. RESULTS: Female patients reported greater impact of food allergy on HRQL than males did. Egg and hazelnut thresholds did not affect HRQL, but lower peanut threshold was associated with worse HRQL. Both parents scored their child's HRQL better than the child's own assessment, but whereas mother-reported HRQL was significantly affected by limitations in the child's social life, father-reported HRQL was affected by limitations in the family's social life. Severity of allergic reaction did not contribute significantly to HRQL. CONCLUSION: The risk of accidental allergen ingestion and limitations in social life are associated with worse HRQL. Fathers provide a unique perspective and should have a greater opportunity to contribute to food allergy research.
BACKGROUND: Studies of children with food allergy typically only include the mother and have not investigated the relationship between the amount of allergen needed to elicit a clinical reaction (threshold) and health-related quality of life (HRQL). Our aims were (i) to compare self-reported and parent-reported HRQL in different age groups, (ii) to evaluate the impact of severity of allergic reaction and threshold on HRQL, and (iii) to investigate factors associated with patient-reported and parent-reported HRQL. METHODS: Age-appropriate Food Allergy Quality of Life Questionnaires (FAQLQ) were completed by 73 children, 49 adolescents and 29 adults with peanut, hazelnut or egg allergy. Parents (197 mothers, 120 fathers) assessed their child's HRQL using the FAQLQ-Parent form. Clinical data and threshold values were obtained from a hospital database. Significant factors for HRQL were investigated using univariate and multivariate regression. RESULTS: Female patients reported greater impact of food allergy on HRQL than males did. Egg and hazelnut thresholds did not affect HRQL, but lower peanut threshold was associated with worse HRQL. Both parents scored their child's HRQL better than the child's own assessment, but whereas mother-reported HRQL was significantly affected by limitations in the child's social life, father-reported HRQL was affected by limitations in the family's social life. Severity of allergic reaction did not contribute significantly to HRQL. CONCLUSION: The risk of accidental allergen ingestion and limitations in social life are associated with worse HRQL. Fathers provide a unique perspective and should have a greater opportunity to contribute to food allergy research.
Authors: Edwin H Kim; Tamara T Perry; Robert A Wood; Donald Y M Leung; M Cecilia Berin; A Wesley Burks; Christine B Cho; Stacie M Jones; Amy Scurlock; Scott H Sicherer; Alice K Henning; Peter Dawson; Robert W Lindblad; Marshall Plaut; Hugh A Sampson Journal: J Allergy Clin Immunol Date: 2020-06-12 Impact factor: 10.793
Authors: Amy M Scurlock; A Wesley Burks; Scott H Sicherer; Donald Y M Leung; Edwin H Kim; Alice K Henning; Peter Dawson; Robert W Lindblad; M Cecilia Berin; Christine B Cho; Wendy F Davidson; Marshall Plaut; Hugh A Sampson; Robert A Wood; Stacie M Jones Journal: J Allergy Clin Immunol Date: 2020-12-05 Impact factor: 10.793
Authors: Francisco Cabrera-Chávez; Cecilia Ivonne Rodríguez-Bellegarrigue; Oscar Gerardo Figueroa-Salcido; Jesús Aristeo Lopez-Gallardo; Jesús Gilberto Arámburo-Gálvez; Marcela de Jesús Vergara-Jiménez; Mónica Lizzette Castro-Acosta; Norberto Sotelo-Cruz; Martina Hilda Gracia-Valenzuela; Noé Ontiveros Journal: Int J Environ Res Public Health Date: 2018-11-02 Impact factor: 3.390
Authors: Victoria Thörnqvist; Roelinde Middelveld; Hay Mar Wai; Natalia Ballardini; Evalill Nilsson; Jennie Strömquist; Staffan Ahlstedt; Lennart Jan Nilsson; Jennifer L P Protudjer Journal: Clin Transl Allergy Date: 2019-02-07 Impact factor: 5.871