Literature DB >> 27936365

How Much Is Too Much? Patterns of Drinking During Alcohol Treatment and Associations With Post-Treatment Outcomes Across Three Alcohol Clinical Trials.

Katie Witkiewitz, Corey R Roos1,2, Matthew R Pearson2, Kevin A Hallgren3, Stephen A Maisto4, Megan Kirouac1,2, Alyssa A Forcehimes2, Adam D Wilson1,2, Charles S Robinson1, Elizabeth McCallion1,2, J Scott Tonigan2, Nick Heather5.   

Abstract

OBJECTIVE: This secondary data analysis examined patterns of drinking during alcohol treatment and associated drinking outcomes during the first year following treatment. The goal was to provide clinicians with guidance on which patients may be most at risk for negative long-term outcomes based on drinking patterns during treatment.
METHOD: This study was an analysis of existing data (N = 3,851) from three randomized clinical trials for alcohol use disorder: the COMBINE Study (n = 1,383), Project MATCH (n = 1,726), and the United Kingdom Alcohol Treatment Trial (n = 742). Indicators of abstinence, non-heavy drinking, and heavy drinking (defined as 4/5 or more drinks per day for women/men) were examined during each week of treatment using repeated-measures latent class analysis. Associations between drinking patterns during treatment and drinking intensity, drinking consequences, and physical and mental health 12 months following intake were examined.
RESULTS: Seven drinking patterns were identified. Patients who engaged in persistent heavy drinking throughout treatment and those who returned to persistent heavy drinking during treatment had the worst long-term outcomes. Patients who engaged in some heavy drinking during treatment had better long-term outcomes than persistent heavy drinkers. Patients who reported low-risk drinking or abstinence had the best long-term outcomes. There were no differences in outcomes between low-risk drinkers and abstainers.
CONCLUSIONS: Abstinence, low-risk drinking, or even some heavy drinking during treatment are associated with the best long-term outcomes. Patients who are engaging in persistent heavy drinking are likely to have the worst outcomes and may require a higher level of care.

Entities:  

Mesh:

Year:  2017        PMID: 27936365      PMCID: PMC5148751          DOI: 10.15288/jsad.2017.78.59

Source DB:  PubMed          Journal:  J Stud Alcohol Drugs        ISSN: 1937-1888            Impact factor:   2.582


  47 in total

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Journal:  Drug Alcohol Depend       Date:  2009-12-06       Impact factor: 4.492

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Authors:  D C Hodgins; G Leigh; R Milne; R Gerrish
Journal:  Addict Behav       Date:  1997 Mar-Apr       Impact factor: 3.913

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Journal:  Addiction       Date:  2011-10-07       Impact factor: 6.526

6.  Integrating person-centered and variable-centered analyses: growth mixture modeling with latent trajectory classes.

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Journal:  Alcohol Clin Exp Res       Date:  2000-06       Impact factor: 3.455

Review 7.  Relapse prevention for alcohol and drug problems: that was Zen, this is Tao.

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Journal:  Am Psychol       Date:  2004 May-Jun

8.  A 6-year follow-up of alcoholics after long-term outpatient treatment.

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Authors:  B T Williams; D C Drummond
Journal:  Drug Alcohol Depend       Date:  1994-06       Impact factor: 4.492

10.  Acceptance of non-abstinence goals by addiction professionals in the United States.

Authors:  Alan K Davis; Harold Rosenberg
Journal:  Psychol Addict Behav       Date:  2012-10-22
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2.  Preresolution Drinking Problem Severity Profiles Associated with Stable Moderation Outcomes of Natural Recovery Attempts.

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5.  Change in DSM-5 Alcohol Use Disorder Criteria Count and Severity Level as a Treatment Outcome Indicator: Results from a Randomized Trial.

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6.  Temporal Stability of Heavy Drinking Days and Drinking Reductions Among Heavy Drinkers in the COMBINE Study.

Authors:  Katie Witkiewitz; Adam D Wilson; Matthew R Pearson; Kevin A Hallgren; Daniel E Falk; Raye Z Litten; Henry R Kranzler; Karl F Mann; Deborah S Hasin; Stephanie S O'Malley; Raymond F Anton
Journal:  Alcohol Clin Exp Res       Date:  2017-04-05       Impact factor: 3.455

7.  A 22-Year Follow-Up (Range 16 to 23) of Original Subjects with Baseline Alcohol Use Disorders from the Collaborative Study on Genetics of Alcoholism.

Authors:  Marc A Schuckit; Tom L Smith; George Danko; John Kramer; Kathleen K Bucholz; Vivia McCutcheon; Grace Chan; Samuel Kuperman; Victor Hesselbrock; Danielle M Dick; Michie Hesselbrock; Bernice Porjesz; Howard J Edenberg; John I Nureberger; Marcy Gregg; Lara Schoen; Mari Kawamura; Lee Anne Mendoza
Journal:  Alcohol Clin Exp Res       Date:  2018-07-05       Impact factor: 3.455

8.  Who achieves low risk drinking during alcohol treatment? An analysis of patients in three alcohol clinical trials.

Authors:  Katie Witkiewitz; Matthew R Pearson; Kevin A Hallgren; Stephen A Maisto; Corey R Roos; Megan Kirouac; Adam D Wilson; Kevin S Montes; Nick Heather
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10.  Remission From Unhealthy Drinking Among Patients With an Alcohol Use Disorder: A Longitudinal Study Using Systematic, Primary Care-Based Alcohol Screening Data.

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