Literature DB >> 27933520

Mouse Genome Informatics (MGI): Resources for Mining Mouse Genetic, Genomic, and Biological Data in Support of Primary and Translational Research.

Janan T Eppig1, Cynthia L Smith2, Judith A Blake2, Martin Ringwald2, James A Kadin2, Joel E Richardson2, Carol J Bult2.   

Abstract

The Mouse Genome Informatics (MGI), resource ( www.informatics.jax.org ) has existed for over 25 years, and over this time its data content, informatics infrastructure, and user interfaces and tools have undergone dramatic changes (Eppig et al., Mamm Genome 26:272-284, 2015). Change has been driven by scientific methodological advances, rapid improvements in computational software, growth in computer hardware capacity, and the ongoing collaborative nature of the mouse genomics community in building resources and sharing data. Here we present an overview of the current data content of MGI, describe its general organization, and provide examples using simple and complex searches, and tools for mining and retrieving sets of data.

Entities:  

Keywords:  Database; Genome informatics; Resources for systems genetics

Mesh:

Year:  2017        PMID: 27933520     DOI: 10.1007/978-1-4939-6427-7_3

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN: 1064-3745


  35 in total

Review 1.  Murine Models of Sepsis and Trauma: Can We Bridge the Gap?

Authors:  Julie A Stortz; Steven L Raymond; Juan C Mira; Lyle L Moldawer; Alicia M Mohr; Philip A Efron
Journal:  ILAR J       Date:  2017-07-01

2.  MARRVEL: Integration of Human and Model Organism Genetic Resources to Facilitate Functional Annotation of the Human Genome.

Authors:  Julia Wang; Rami Al-Ouran; Yanhui Hu; Seon-Young Kim; Ying-Wooi Wan; Michael F Wangler; Shinya Yamamoto; Hsiao-Tuan Chao; Aram Comjean; Stephanie E Mohr; Norbert Perrimon; Zhandong Liu; Hugo J Bellen
Journal:  Am J Hum Genet       Date:  2017-05-11       Impact factor: 11.025

3.  A fully-automated method discovers loss of mouse-lethal and human-monogenic disease genes in 58 mammals.

Authors:  Yatish Turakhia; Heidi I Chen; Amir Marcovitz; Gill Bejerano
Journal:  Nucleic Acids Res       Date:  2020-09-18       Impact factor: 16.971

4.  Endophenotype-based in silico network medicine discovery combined with insurance record data mining identifies sildenafil as a candidate drug for Alzheimer's disease.

Authors:  Jiansong Fang; Pengyue Zhang; Yadi Zhou; Chien-Wei Chiang; Juan Tan; Yuan Hou; Shaun Stauffer; Lang Li; Andrew A Pieper; Jeffrey Cummings; Feixiong Cheng
Journal:  Nat Aging       Date:  2021-12-06

5.  Centralizing neurofibromatosis experimental tool knowledge with the NF Research Tools Database.

Authors:  Ashley Clayton; Mialy DeFelice; Brynn Zalmanek; Jay Hodgson; Caroline Morin; Stockard Simon; Julie A Bletz; James A Eddy; Milen Nikolov; Jineta Banerjee; Kalyan Vinnakota; Marco Marasca; Kevin J Boske; Bruce Hoff; Ljubomir Bradic; YooRi Kim; James R Goss; Robert J Allaway
Journal:  Database (Oxford)       Date:  2022-06-23       Impact factor: 4.462

6.  Global landscape of mouse and human cytokine transcriptional regulation.

Authors:  Sebastian Carrasco Pro; Alvaro Dafonte Imedio; Clarissa Stephanie Santoso; Kok Ann Gan; Jared Allan Sewell; Melissa Martinez; Rebecca Sereda; Shivani Mehta; Juan Ignacio Fuxman Bass
Journal:  Nucleic Acids Res       Date:  2018-10-12       Impact factor: 16.971

7.  PATHBIO: an international training program for precision mouse phenotyping.

Authors:  Jesus Ruberte; Paul N Schofield; Cord Brakebusch; Peter Vogel; Yann Herault; Guillem Gracia; Colin McKerlie; Martin Hrabĕ de Angelis; Michael Hagn; John P Sundberg
Journal:  Mamm Genome       Date:  2020-02-22       Impact factor: 2.957

8.  Genome-wide association study meta-analysis for quantitative ultrasound parameters of bone identifies five novel loci for broadband ultrasound attenuation.

Authors:  Benjamin H Mullin; Jing Hua Zhao; Suzanne J Brown; John R B Perry; Jian'an Luan; Hou-Feng Zheng; Claudia Langenberg; Frank Dudbridge; Robert Scott; Nick J Wareham; Tim D Spector; J Brent Richards; John P Walsh; Scott G Wilson
Journal:  Hum Mol Genet       Date:  2017-07-15       Impact factor: 6.150

9.  SwissBioPics-an interactive library of cell images for the visualization of subcellular location data.

Authors:  Philippe Le Mercier; Jerven Bolleman; Edouard de Castro; Elisabeth Gasteiger; Parit Bansal; Andrea H Auchincloss; Emmanuel Boutet; Lionel Breuza; Cristina Casals-Casas; Anne Estreicher; Marc Feuermann; Damien Lieberherr; Catherine Rivoire; Ivo Pedruzzi; Nicole Redaschi; Alan Bridge
Journal:  Database (Oxford)       Date:  2022-04-12       Impact factor: 4.462

10.  A Mild PUM1 Mutation Is Associated with Adult-Onset Ataxia, whereas Haploinsufficiency Causes Developmental Delay and Seizures.

Authors:  Vincenzo A Gennarino; Elizabeth E Palmer; Laura M McDonell; Li Wang; Carolyn J Adamski; Amanda Koire; Lauren See; Chun-An Chen; Christian P Schaaf; Jill A Rosenfeld; Jessica A Panzer; Ute Moog; Shuang Hao; Ann Bye; Edwin P Kirk; Pawel Stankiewicz; Amy M Breman; Arran McBride; Tejaswi Kandula; Holly A Dubbs; Rebecca Macintosh; Michael Cardamone; Ying Zhu; Kevin Ying; Kerith-Rae Dias; Megan T Cho; Lindsay B Henderson; Berivan Baskin; Paula Morris; Jiang Tao; Mark J Cowley; Marcel E Dinger; Tony Roscioli; Oana Caluseriu; Oksana Suchowersky; Rani K Sachdev; Olivier Lichtarge; Jianrong Tang; Kym M Boycott; J Lloyd Holder; Huda Y Zoghbi
Journal:  Cell       Date:  2018-02-22       Impact factor: 66.850

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