Mateusz Wichtowski1, Paweł Potocki2, Joanna Kufel-Grabowska3, Joanna Streb2, Dawid Murawa4. 1. Oncological and General Surgery Ward I, the Greater Poland Cancer Center, Poznan, Poland, Poznan, Poland. 2. Oncology Department, University Hospital, Śniadeckich 10, Kraków, Poland, Poznan, Poland. 3. Chemotherapy Ward, the Greater Poland Cancer Center, Poznan, Poland. 4. Oncological and General Surgery Ward I, the Greater Poland Cancer Center, Poznan, Poland, Poznan, Poland; Provincial Specialist Hospital in Wrocław, Research and Development Center, Wrocław, Poland, Poznan, Poland.
Abstract
BACKGROUND: Chest wall recurrence (CWR) from breast cancer after mastectomy is a difficult to treat disease. Electrochemotherapy (ECT) provides a safe, efficient, and non-invasive locoregional treatment approach in this setting. CASE REPORT: A 61-year-old woman presented with unresectable breast cancer recurrence to the skin and subcutaneous tissue for which numerous lines of treatment were unsuccessful. Between February 2015 and May 2015, the patient underwent 3 courses of ECT after which a spectacular regression of the cutaneous metastatic foci was observed. After an overall observation period of 12 weeks, complete clinical remission was achieved. CONCLUSION: ECT can be proposed as an effective and safe locoregional therapy for breast cancer CWR and provides an alternative treatment modality to conventional therapies, especially in the case of multiple cutaneous and subcutaneous lesions.
BACKGROUND: Chest wall recurrence (CWR) from breast cancer after mastectomy is a difficult to treat disease. Electrochemotherapy (ECT) provides a safe, efficient, and non-invasive locoregional treatment approach in this setting. CASE REPORT: A 61-year-old woman presented with unresectable breast cancer recurrence to the skin and subcutaneous tissue for which numerous lines of treatment were unsuccessful. Between February 2015 and May 2015, the patient underwent 3 courses of ECT after which a spectacular regression of the cutaneous metastatic foci was observed. After an overall observation period of 12 weeks, complete clinical remission was achieved. CONCLUSION: ECT can be proposed as an effective and safe locoregional therapy for breast cancer CWR and provides an alternative treatment modality to conventional therapies, especially in the case of multiple cutaneous and subcutaneous lesions.
Entities:
Keywords:
Bleomycin; Breast cancer; Chest wall recurrence; Electrochemotherapy
Authors: L M Mir; M Belehradek; C Domenge; S Orlowski; B Poddevin; J Belehradek; G Schwaab; B Luboinski; C Paoletti Journal: C R Acad Sci III Date: 1991
Authors: Adriana Leticia Vera-Tizatl; Claudia Elizabeth Vera-Tizatl; Arturo Vera-Hernández; Lorenzo Leija-Salas; Sergio Rodríguez; Damijan Miklavčič; Bor Kos Journal: Technol Cancer Res Treat Date: 2018-01-01