Literature DB >> 1723647

[Electrochemotherapy, a new antitumor treatment: first clinical trial].

L M Mir1, M Belehradek, C Domenge, S Orlowski, B Poddevin, J Belehradek, G Schwaab, B Luboinski, C Paoletti.   

Abstract

Electrochemotherapy (ECT) is a new antitumor treatment which consists in delivering electric pulses to the tumor some minutes after an intravenous injection of bleomycin. We report here the first clinical trial of ECT, applied to patients with permeation nodules of head and neck squamous carcinomas. ECT was well tolerated by patients, no serious incident occurred and a clear antitumor efficiency was found.

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Year:  1991        PMID： 1723647

Source DB:  PubMed          Journal:  C R Acad Sci III        ISSN： 0764-4469


  59 in total

1.  Electroporation-based technologies and treatments.

Authors:  Damijan Miklavcic; Lluis M Mir; P Thomas Vernier
Journal:  J Membr Biol       Date:  2010-07       Impact factor: 1.843

2.  Use of collagen gel as a three-dimensional in vitro model to study electropermeabilization and gene electrotransfer.

Authors:  Sasa Haberl; Mojca Pavlin
Journal:  J Membr Biol       Date:  2010-07-18       Impact factor: 1.843

3.  Calcium electroporation induces tumor eradication, long-lasting immunity and cytokine responses in the CT26 colon cancer mouse model.

Authors:  Hanne Falk; Patrick F Forde; Marie Lund Bay; Uma Maheswari Mangalanathan; Pernille Hojman; Declan M Soden; Julie Gehl
Journal:  Oncoimmunology       Date:  2017-03-17       Impact factor: 8.110

Review 4.  Membrane perturbation by an external electric field: a mechanism to permit molecular uptake.

Authors:  J-M Escoffre; D S Dean; M Hubert; M-P Rols; C Favard
Journal:  Eur Biophys J       Date:  2007-06-19       Impact factor: 1.733

Review 5.  Electroporation for the delivery of DNA-based vaccines and immunotherapeutics: current clinical developments.

Authors:  Angela M Bodles-Brakhop; Richard Heller; Ruxandra Draghia-Akli
Journal:  Mol Ther       Date:  2009-02-17       Impact factor: 11.454

Review 6.  Physical methods of nucleic acid transfer: general concepts and applications.

Authors:  Julien Villemejane; Lluis M Mir
Journal:  Br J Pharmacol       Date:  2009-01-21       Impact factor: 8.739

Review 7.  What is (still not) known of the mechanism by which electroporation mediates gene transfer and expression in cells and tissues.

Authors:  Jean-Michel Escoffre; Thomas Portet; Luc Wasungu; Justin Teissié; David Dean; Marie-Pierre Rols
Journal:  Mol Biotechnol       Date:  2008-11-18       Impact factor: 2.695

Review 8.  Nucleic acids electrotransfer-based gene therapy (electrogenetherapy): past, current, and future.

Authors:  L M Mir
Journal:  Mol Biotechnol       Date:  2009-06-27       Impact factor: 2.695

Review 9.  [Value of galvanotherapy for localised prostate cancer].

Authors:  C Arsov; C Winter; P Albers
Journal:  Urologe A       Date:  2009-07       Impact factor: 0.639

Review 10.  Electrochemotherapy for treatment of skin and soft tissue tumours. Update and definition of its role in multimodal therapy.

Authors:  Vicente Muñoz Madero; Gloria Ortega Pérez
Journal:  Clin Transl Oncol       Date:  2011-01       Impact factor: 3.405
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