Literature DB >> 27914000

From transformation to metastasis: deconstructing the extracellular matrix in breast cancer.

Shelly Kaushik1, Michael W Pickup1, Valerie M Weaver2,3,4,5,6,7.   

Abstract

The extracellular matrix (ECM) is a guiding force that regulates various developmental stages of the breast. In addition to providing structural support for the cells, it mediates epithelial-stromal communication and provides cues for cell survival, proliferation, and differentiation. Perturbations in ECM architecture profoundly influence breast tumor progression and metastasis. Understanding how a dysregulated ECM can facilitate malignant transformation is crucial to designing treatments to effectively target the tumor microenvironment. Here, we address the contribution of ECM mechanics to breast cancer progression, metastasis, and treatment resistance and discuss potential therapeutic strategies targeting the ECM.

Entities:  

Keywords:  Breast cancer; Desmoplasia; Extracellular matrix (ECM); Mechanosignaling; Metastasis; Treatment resistance

Mesh：

Year:  2016        PMID： 27914000      PMCID： PMC5215979          DOI： 10.1007/s10555-016-9650-0

Source DB:  PubMed          Journal:  Cancer Metastasis Rev        ISSN： 0167-7659            Impact factor:   9.264


  120 in total

1.  Myeloid progenitor cells in the premetastatic lung promote metastases by inducing mesenchymal to epithelial transition.

Authors:  Dingcheng Gao; Natasha Joshi; Hyejin Choi; Seongho Ryu; Mary Hahn; Raul Catena; Helen Sadik; Pedram Argani; Patrick Wagner; Linda T Vahdat; Jeffrey L Port; Brendon Stiles; Saraswati Sukumar; Nasser K Altorki; Shahin Rafii; Vivek Mittal
Journal:  Cancer Res       Date:  2012-01-26       Impact factor: 12.701

2.  Differential expression of cancer-associated fibroblast-related proteins according to molecular subtype and stromal histology in breast cancer.

Authors:  Sung Yeon Park; Hye Min Kim; Ja Seung Koo
Journal:  Breast Cancer Res Treat       Date:  2015-02-10       Impact factor: 4.872

3.  Aberrant type I and type III collagen gene expression in human breast cancer in vivo.

Authors:  S Kauppila; F Stenbäck; J Risteli; A Jukkola; L Risteli
Journal:  J Pathol       Date:  1998-11       Impact factor: 7.996

4.  Force engages vinculin and promotes tumor progression by enhancing PI3K activation of phosphatidylinositol (3,4,5)-triphosphate.

Authors:  Matthew G Rubashkin; Luke Cassereau; Russell Bainer; Christopher C DuFort; Yoshihiro Yui; Guanqing Ou; Matthew J Paszek; Michael W Davidson; Yunn-Yi Chen; Valerie M Weaver
Journal:  Cancer Res       Date:  2014-09-01       Impact factor: 12.701

Review 5.  β1-integrin: a potential therapeutic target in the battle against cancer recurrence.

Authors:  Dalit Barkan; Ann F Chambers
Journal:  Clin Cancer Res       Date:  2011-09-07       Impact factor: 12.531

Review 6.  Bi-directional signaling: extracellular matrix and integrin regulation of breast tumor progression.

Authors:  Scott Gehler; Suzanne M Ponik; Kristin M Riching; Patricia J Keely
Journal:  Crit Rev Eukaryot Gene Expr       Date:  2013       Impact factor: 1.807

7.  Systemic spread is an early step in breast cancer.

Authors:  Yves Hüsemann; Jochen B Geigl; Falk Schubert; Piero Musiani; Manfred Meyer; Elke Burghart; Guido Forni; Roland Eils; Tanja Fehm; Gert Riethmüller; Christoph A Klein
Journal:  Cancer Cell       Date:  2008-01       Impact factor: 31.743

8.  Immunohistochemical study of type I collagen and type I pN-collagen in benign and malignant ovarian neoplasms.

Authors:  G G Zhu; L Risteli; M Mäkinen; J Risteli; A Kauppila; F Stenbäck
Journal:  Cancer       Date:  1995-02-15       Impact factor: 6.860

Review 9.  Tumour-stromal interactions. Integrins and cell adhesions as modulators of mammary cell survival and transformation.

Authors:  M A Chrenek; P Wong; V M Weaver
Journal:  Breast Cancer Res       Date:  2001-06-14       Impact factor: 6.466

10.  Metastatic breast cancer cells in lymph nodes increase nodal collagen density.

Authors:  Asif Rizwan; Camille Bulte; Anusha Kalaichelvan; Menglin Cheng; Balaji Krishnamachary; Zaver M Bhujwalla; Lu Jiang; Kristine Glunde
Journal:  Sci Rep       Date:  2015-05-07       Impact factor: 4.379
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  60 in total

Review 1.  Effects of the Tumor Environment on Ion Channels: Implication for Breast Cancer Progression.

Authors:  Halima Ouadid-Ahidouch; Hamid Morjani; Julie Schnipper; Alban Girault; Ahmed Ahidouch
Journal:  Rev Physiol Biochem Pharmacol       Date:  2021       Impact factor: 5.545

Review 2.  Fibrous stroma: Driver and passenger in cancer development.

Authors:  Vandana Sharma; Joshua Letson; Saori Furuta
Journal:  Sci Signal       Date:  2022-03-08       Impact factor: 8.192

Review 3.  Cell-extracellular matrix dynamics.

Authors:  Andrew D Doyle; Shayan S Nazari; Kenneth M Yamada
Journal:  Phys Biol       Date:  2022-01-12       Impact factor: 2.583

4.  Electromechanical Coupling Factor of Breast Tissue as a Biomarker for Breast Cancer.

Authors:  Kihan Park; Wenjin Chen; Marina A Chekmareva; David J Foran; Jaydev P Desai
Journal:  IEEE Trans Biomed Eng       Date:  2017-04-19       Impact factor: 4.538

5.  Distinguishing metastatic triple-negative breast cancer from nonmetastatic breast cancer using second harmonic generation imaging and resonance Raman spectroscopy.

Authors:  Ethan Bendau; Jason Smith; Lin Zhang; Ellen Ackerstaff; Natalia Kruchevsky; Binlin Wu; Jason A Koutcher; Robert Alfano; Lingyan Shi
Journal:  J Biophotonics       Date:  2020-04-20       Impact factor: 3.207

6.  Microengineered 3D Collagen Gels with Independently Tunable Fiber Anisotropy and Directionality.

Authors:  Adeel Ahmed; Indranil M Joshi; Stephen Larson; Mehran Mansouri; Shayan Gholizadeh; Zahra Allahyari; Farzad Forouzandeh; David A Borkholder; Thomas R Gaborski; Vinay V Abhyankar
Journal:  Adv Mater Technol       Date:  2021-03-10

Review 7.  Every step of the way: integrins in cancer progression and metastasis.

Authors:  Hellyeh Hamidi; Johanna Ivaska
Journal:  Nat Rev Cancer       Date:  2018-09       Impact factor: 60.716

8.  Sulindac, a Nonselective NSAID, Reduces Breast Density in Postmenopausal Women with Breast Cancer Treated with Aromatase Inhibitors.

Authors:  Patricia A Thompson; Chuan Huang; Jie Yang; Betsy C Wertheim; Denise Roe; Xiaoyue Zhang; Jie Ding; Pavani Chalasani; Christina Preece; Jessica Martinez; H-H Sherry Chow; Alison T Stopeck
Journal:  Clin Cancer Res       Date:  2021-06-10       Impact factor: 12.531

9.  Generation of 3D Tumor Spheroids with Encapsulating Basement Membranes for Invasion Studies.

Authors:  Shayan S Nazari
Journal:  Curr Protoc Cell Biol       Date:  2020-06

10.  Loss of Nitric Oxide Induces Fibrogenic Response in Organotypic 3D Co-Culture of Mammary Epithelia and Fibroblasts-An Indicator for Breast Carcinogenesis.

Authors:  Gang Ren; Xunzhen Zheng; Vandana Sharma; Joshua Letson; Andrea L Nestor-Kalinoski; Saori Furuta
Journal:  Cancers (Basel)       Date:  2021-06-05       Impact factor: 6.639
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