Literature DB >> 27908921

Wartime toxin exposure: recognising the silent killer.

Kamran Khan1, Susan E Wozniak1, JoAnn Coleman2, Mukund S Didolkar3.   

Abstract

Wartime toxin exposures have been implicated in the genesis of malignancy in war veterans. Agent Orange, one toxin among many, has been linked to malignancy and the subcomponent phenoxyacetic acid has been associated with soft tissue sarcomas (STSs). This case demonstrates the association between a wartime toxin exposure (Agent Orange) and subsequent cancer development. Ultimately, we aim to highlight the importance of simple, specific questions in the patient history to account for previous wartime toxin exposures. 2016 BMJ Publishing Group Ltd.

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Year:  2016        PMID： 27908921      PMCID： PMC5174831          DOI： 10.1136/bcr-2016-217438

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN： 1757-790X


  28 in total

1.  Cancer mortality in workers exposed to phenoxy herbicides, chlorophenols, and dioxins. An expanded and updated international cohort study.

Authors:  M Kogevinas; H Becher; T Benn; P A Bertazzi; P Boffetta; H B Bueno-de-Mesquita; D Coggon; D Colin; D Flesch-Janys; M Fingerhut; L Green; T Kauppinen; M Littorin; E Lynge; J D Mathews; M Neuberger; N Pearce; R Saracci
Journal:  Am J Epidemiol       Date:  1997-06-15       Impact factor: 4.897

2.  Soft tissue sarcomas and chlorinated phenols.

Authors:  F E Johnson; M A Kugler; S M Brown
Journal:  Lancet       Date:  1981-07-04       Impact factor: 79.321

3.  Dioxin, chloracne, and soft tissue sarcoma.

Authors:  R R Cook
Journal:  Lancet       Date:  1981-03-14       Impact factor: 79.321

4.  Thoracic soft-tissue sarcoma in Vietnam veterans exposed to Agent Orange.

Authors:  P R Sarma; J Jacobs
Journal:  N Engl J Med       Date:  1982-05-06       Impact factor: 91.245

5.  Soft tissue sarcoma and military service in Vietnam: a case-control study.

Authors:  H Kang; F M Enzinger; P Breslin; M Feil; Y Lee; B Shepard; F Enziger
Journal:  J Natl Cancer Inst       Date:  1987-10       Impact factor: 13.506

6.  Soft tissue sarcoma and occupational exposures.

Authors:  G Wingren; M Fredrikson; H N Brage; B Nordenskjöld; O Axelson
Journal:  Cancer       Date:  1990-08-15       Impact factor: 6.860

7.  Pleomorphic liposarcoma: clinical observations and molecular variables.

Authors:  Markus P Ghadimi; Ping Liu; Tingsheng Peng; Svetlana Bolshakov; Eric D Young; Keila E Torres; Chiara Colombo; Aviad Hoffman; Dominique Broccoli; Jason L Hornick; Alexander J Lazar; Peter Pisters; Raphael E Pollock; Dina Lev
Journal:  Cancer       Date:  2011-05-19       Impact factor: 6.860

8.  Soft tissue sarcomas, phenoxy herbicides, and chlorinated phenols.

Authors:  M Moses; I J Selikoff
Journal:  Lancet       Date:  1981-06-20       Impact factor: 79.321

9.  Agent Orange Exposure and Monoclonal Gammopathy of Undetermined Significance: An Operation Ranch Hand Veteran Cohort Study.

Authors:  Ola Landgren; Youn K Shim; Joel Michalek; Rene Costello; Debra Burton; Norma Ketchum; Katherine R Calvo; Neil Caporaso; Elizabeth Raveche; Dan Middleton; Gerald Marti; Robert F Vogt
Journal:  JAMA Oncol       Date:  2015-11       Impact factor: 31.777

10.  Sarcomas of soft tissues after Vietnam service.

Authors:  P Greenwald; B Kovasznay; D N Collins; G Therriault
Journal:  J Natl Cancer Inst       Date:  1984-11       Impact factor: 13.506
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  2 in total

Review 1.  Establishing a role for environmental toxicant exposure induced epigenetic remodeling in malignant transformation.

Authors:  Kristen M Humphrey; Sumali Pandey; Jeffery Martin; Tamara Hagoel; Anne Grand'Maison; Joyce E Ohm
Journal:  Semin Cancer Biol       Date:  2018-11-16       Impact factor: 15.707

Review 2.  A perspective on persistent toxicants in veterans and amyotrophic lateral sclerosis: identifying exposures determining higher ALS risk.

Authors:  Diane B Re; Beizhan Yan; Lilian Calderón-Garcidueñas; Angeline S Andrew; Maeve Tischbein; Elijah W Stommel
Journal:  J Neurol       Date:  2022-01-01       Impact factor: 6.682
  2 in total

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