Literature DB >> 27906550

Delayed Diagnosis and a Lack of Information Associated With Dissatisfaction in Women With Polycystic Ovary Syndrome.

Melanie Gibson-Helm1, Helena Teede1,2, Andrea Dunaif3, Anuja Dokras4.   

Abstract

Context: Polycystic ovary syndrome (PCOS) is a complex, chronic, and under-recognized disorder. Diagnosis experience may have lasting effects on well-being and self-management. Objective: To investigate PCOS diagnosis experiences, information provided, and concerns about PCOS. Design: Cross-sectional study using an online questionnaire. Setting: Recruitment via support group web sites in 2015 to 2016. Participants: There were 1385 women with a reported diagnosis of PCOS who were living in North America (53.0%), Europe (42.2%), or other world regions (4.9%); of these, 64.8% were 18 to 35 years of age. Main Outcome Measures: Satisfaction with PCOS diagnosis experience, satisfaction with PCOS information received at the time of diagnosis, and current concerns about PCOS.
Results: One-third or more of women reported >2 years (33.6%) and ≥3 health professionals (47.1%) before a diagnosis was established. Few were satisfied with their diagnosis experience (35.2%) or with the information they received (15.6%). Satisfaction with information received was positively associated with diagnosis satisfaction [odds ratio (OR), 7.0; 95% confidence interval (CI), 4.9 to 9.9]; seeing ≥5 health professionals (OR, 0.5; 95% CI, 0.3 to 0.8) and longer time to diagnosis (>2 years; OR, 0.4; 95% CI, 0.3 to 0.6) were negatively associated with diagnosis satisfaction (independent of time since diagnosis, age, and world region). Women's most common concerns were difficulty losing weight (53.6%), irregular menstrual cycles (50.8%), and infertility (44.5%). Conclusions: In the largest study of PCOS diagnosis experiences, many women reported delayed diagnosis and inadequate information. These gaps in early diagnosis, education, and support are clear opportunities for improving patient experience.
Copyright © 2017 by the Endocrine Society

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Year:  2017        PMID: 27906550      PMCID: PMC6283441          DOI: 10.1210/jc.2016-2963

Source DB:  PubMed          Journal:  J Clin Endocrinol Metab        ISSN: 0021-972X            Impact factor:   5.958


  34 in total

1.  Assessment and management of polycystic ovary syndrome: summary of an evidence-based guideline.

Authors:  Helena J Teede; Marie L Misso; Amanda A Deeks; Lisa J Moran; Bronwyn G A Stuckey; Jennifer L A Wong; Robert J Norman; Michael F Costello
Journal:  Med J Aust       Date:  2011-09-19       Impact factor: 7.738

2.  Quality of life and psychological morbidity in women with polycystic ovary syndrome: body mass index, age and the provision of patient information are significant modifiers.

Authors:  H L Ching; V Burke; B G A Stuckey
Journal:  Clin Endocrinol (Oxf)       Date:  2007-03       Impact factor: 3.478

Review 3.  Impaired glucose tolerance, type 2 diabetes and metabolic syndrome in polycystic ovary syndrome: a systematic review and meta-analysis.

Authors:  Lisa J Moran; Marie L Misso; Robert A Wild; Robert J Norman
Journal:  Hum Reprod Update       Date:  2010-02-16       Impact factor: 15.610

Review 4.  Health care-related economic burden of the polycystic ovary syndrome during the reproductive life span.

Authors:  Ricardo Azziz; Catherine Marin; Lalima Hoq; Enkhe Badamgarav; Paul Song
Journal:  J Clin Endocrinol Metab       Date:  2005-06-08       Impact factor: 5.958

Review 5.  The Androgen Excess and PCOS Society criteria for the polycystic ovary syndrome: the complete task force report.

Authors:  Ricardo Azziz; Enrico Carmina; Didier Dewailly; Evanthia Diamanti-Kandarakis; Héctor F Escobar-Morreale; Walter Futterweit; Onno E Janssen; Richard S Legro; Robert J Norman; Ann E Taylor; Selma F Witchel
Journal:  Fertil Steril       Date:  2008-10-23       Impact factor: 7.329

6.  Development of a health-related quality-of-life questionnaire (PCOSQ) for women with polycystic ovary syndrome (PCOS).

Authors:  L Cronin; G Guyatt; L Griffith; E Wong; R Azziz; W Futterweit; D Cook; A Dunaif
Journal:  J Clin Endocrinol Metab       Date:  1998-06       Impact factor: 5.958

7.  A low intensity, community based lifestyle programme to prevent weight gain in women with young children: cluster randomised controlled trial.

Authors:  Catherine Lombard; Amanda Deeks; Damien Jolley; Kylie Ball; Helena Teede
Journal:  BMJ       Date:  2010-07-13

8.  Diagnostic and treatment characteristics of polycystic ovary syndrome: descriptive measurements of patient perception and awareness from 657 confidential self-reports.

Authors:  E Scott Sills; Mark Perloe; Michael J Tucker; Carolyn R Kaplan; Marc Georges Genton; Glenn L Schattman
Journal:  BMC Womens Health       Date:  2001       Impact factor: 2.809

9.  A qualitative investigation of the impact of peer to peer online support for women living with polycystic ovary syndrome.

Authors:  Sarah Holbrey; Neil S Coulson
Journal:  BMC Womens Health       Date:  2013-12-17       Impact factor: 2.809

10.  Genome-wide association of polycystic ovary syndrome implicates alterations in gonadotropin secretion in European ancestry populations.

Authors:  M Geoffrey Hayes; Margrit Urbanek; David A Ehrmann; Loren L Armstrong; Ji Young Lee; Ryan Sisk; Tugce Karaderi; Thomas M Barber; Mark I McCarthy; Stephen Franks; Cecilia M Lindgren; Corrine K Welt; Evanthia Diamanti-Kandarakis; Dimitrios Panidis; Mark O Goodarzi; Ricardo Azziz; Yi Zhang; Roland G James; Michael Olivier; Ahmed H Kissebah; Elisabet Stener-Victorin; Richard S Legro; Andrea Dunaif
Journal:  Nat Commun       Date:  2015-08-18       Impact factor: 14.919

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  67 in total

1.  Serum homocysteine is associated with polycystic ovarian syndrome in Jordan.

Authors:  Nesreen Saadeh; Mahmoud A Alfaqih; Haneen Mansour; Yousef S Khader; Rami Saadeh; Ahmed Al-Dwairi; Mohamad Nusier
Journal:  Biomed Rep       Date:  2018-09-13

2.  Commentary: Mendelian randomization and women's health.

Authors:  Jenny C Censin; Jonas Bovijn; Michael V Holmes; Cecilia M Lindgren
Journal:  Int J Epidemiol       Date:  2019-06-01       Impact factor: 7.196

3.  Worldwide Dissatisfaction With the Diagnostic Process and Initial Treatment of PCOS.

Authors:  Melanie Cree-Green
Journal:  J Clin Endocrinol Metab       Date:  2017-02-01       Impact factor: 5.958

4.  Increased odds of disordered eating in polycystic ovary syndrome: a systematic review and meta-analysis.

Authors:  Iris Lee; Laura G Cooney; Shailly Saini; Mary D Sammel; Kelly C Allison; Anuja Dokras
Journal:  Eat Weight Disord       Date:  2018-06-26       Impact factor: 4.652

5.  Polycystic ovarian syndrome: an under-recognised problem?

Authors:  Sarah C Hillman; Jeremy Dale
Journal:  Br J Gen Pract       Date:  2018-05       Impact factor: 5.386

6.  A Commentary on the New Evidence-Based Lifestyle Recommendations for Patients with Polycystic Ovary Syndrome and Potential Barriers to Their Implementation in the United States.

Authors:  Brittany Y Jarrett; Annie W Lin; Marla E Lujan
Journal:  J Acad Nutr Diet       Date:  2018-12-12       Impact factor: 4.910

Review 7.  Cardiometabolic Features of Polycystic Ovary Syndrome: Role of Androgens.

Authors:  Licy L Yanes Cardozo; Damian G Romero; Jane F Reckelhoff
Journal:  Physiology (Bethesda)       Date:  2017-09

8.  Exercise Recommendations for Women with Polycystic Ovary Syndrome: Is the Evidence Enough?

Authors:  Nigel K Stepto; Rhiannon K Patten; Eliza C Tassone; Marie L Misso; Leah Brennan; Jacqueline Boyle; Russell A Boyle; Cheryce L Harrison; Angelica Lindén Hirschberg; Kate Marsh; Alba Moreno-Asso; Leanne Redman; Mala Thondan; Chandrika Wijeyaratne; Helena J Teede; Lisa J Moran
Journal:  Sports Med       Date:  2019-08       Impact factor: 11.136

9.  Effect of GLP-1 Receptor Agonists in the Cardiometabolic Complications in a Rat Model of Postmenopausal PCOS.

Authors:  Edgar D Torres Fernandez; Alexandra M Huffman; Maryam Syed; Damian G Romero; Licy L Yanes Cardozo
Journal:  Endocrinology       Date:  2019-12-01       Impact factor: 4.736

10.  Women's experiences of diagnosis and management of polycystic ovary syndrome: a mixed-methods study in general practice.

Authors:  Sarah C Hillman; Carol Bryce; Rishi Caleyachetty; Jeremy Dale
Journal:  Br J Gen Pract       Date:  2020-04-30       Impact factor: 5.386

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