| Literature DB >> 27894983 |
Abi Manesh1, Veeraraghavan Balaji2, Devanga Ragupathi Naveen Kumar3, Priscilla Rupali4.
Abstract
Typhoid fever remains a serious problem in many developing countries. Due to resistance to multiple first line drugs, azithromycin has evolved as an important drug in the treatment of typhoid. While therapy with azithromycin is highly effective, no clinically validated mean inhibitory concentration (MIC) break points or disc diffusion cutoff guidelines are available so far. We describe an Indian adult with clinical and microbiological failure to azithromycin despite low azithromycin MIC.Entities:
Keywords: Azithromycin; MIC within susceptible range; Salmonella enterica serotype Typhi; clinical failure
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Year: 2016 PMID: 27894983 DOI: 10.1016/j.ijid.2016.11.409
Source DB: PubMed Journal: Int J Infect Dis ISSN: 1201-9712 Impact factor: 3.623