Literature DB >> 27892639

Converting Red Blood Cells to Efficient Microreactors for Blood Detoxification.

Can Xu1,2, Xiangyu Yang2, Xiao Fu2, Rui Tian2, Orit Jacobson2, Zhantong Wang2, Nan Lu2, Yijing Liu2, Wenpei Fan2, Fuwu Zhang2, Gang Niu2, Shuo Hu1, Iqbal Unnisa Ali2, Xiaoyuan Chen2.   

Abstract

A simple method to convert red blood cells (RBCs) into efficient microreactors is reported. Triton X-100 is employed at finely tuned concentrations to render RBCs highly permeable to substrates, while low concentrations of glutaraldehyde are used to stabilize cells. The ability for blood detoxification of these microreactors is demonstrated.
© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  Triton X-100 (TX); blood detoxification; glutaraldehyde (GA); microreactors; red blood cells (RBC)

Mesh:

Substances:

Year:  2016        PMID: 27892639      PMCID: PMC5293620          DOI: 10.1002/adma.201603673

Source DB:  PubMed          Journal:  Adv Mater        ISSN: 0935-9648            Impact factor:   30.849


  53 in total

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