Giovanna E Carpagnano1, Maria P Foschino-Barbaro2, Corrado Crocetta3, Donato Lacedonia2, Valerio Saliani2, Luigi Davide Zoppo2, Peter J Barnes4. 1. Department of Medical and Surgical Sciences, Institute of Respiratory Diseases, University of Foggia, Italy. Electronic address: giovannaelisiana.carpagnano@unifg.it. 2. Department of Medical and Surgical Sciences, Institute of Respiratory Diseases, University of Foggia, Italy. 3. Section of Statistics, Faculty of Economics, University of Foggia, Italy. 4. Airway Disease Section, National Heart and Lung Institute, Imperial College London, Royal Brompton Hospital, London, UK.
Abstract
BACKGROUND: Exhaled breath temperature (EBT) is a new noninvasive method for the study of inflammatory respiratory diseases with a potential to reach clinical practice. However, few studies are available regarding the validation of this method, and they were mainly derived from small, pediatric populations; thus, the range of normal values is not well established. The aim of this study was to measure EBT values in an Italian population of 298 subjects (mean age, 45.2 ± 15.5 years; 143 male subjects; FEV1, 97.2% ± 5.8%; FVC, 98.4% ± 3.9%) selected from 867 adult volunteers to define reference values in healthy subjects and to analyze the influence of individual and external variables on this parameter. METHODS: EBT was measured with an X-halo PRO device to different ambient temperature ranging from 0°C to 38°C. RESULTS: We report reference values of EBT in healthy white subjects who had never smoked. EBT values were strongly influenced by the external temperature and to a lesser extent according to sex. CONCLUSIONS: In a large population of healthy subjects who never smoked, these data provide reference values for measuring EBT as a basis for future studies. Our results are contribute to the promotion of EBT from "bench" to "bedside."
BACKGROUND: Exhaled breath temperature (EBT) is a new noninvasive method for the study of inflammatory respiratory diseases with a potential to reach clinical practice. However, few studies are available regarding the validation of this method, and they were mainly derived from small, pediatric populations; thus, the range of normal values is not well established. The aim of this study was to measure EBT values in an Italian population of 298 subjects (mean age, 45.2 ± 15.5 years; 143 male subjects; FEV1, 97.2% ± 5.8%; FVC, 98.4% ± 3.9%) selected from 867 adult volunteers to define reference values in healthy subjects and to analyze the influence of individual and external variables on this parameter. METHODS:EBT was measured with an X-halo PRO device to different ambient temperature ranging from 0°C to 38°C. RESULTS: We report reference values of EBT in healthy white subjects who had never smoked. EBT values were strongly influenced by the external temperature and to a lesser extent according to sex. CONCLUSIONS: In a large population of healthy subjects who never smoked, these data provide reference values for measuring EBT as a basis for future studies. Our results are contribute to the promotion of EBT from "bench" to "bedside."
Authors: Giovanna Elisiana Carpagnano; Todor A Popov; Giulia Scioscia; Nicoletta Pia Ardò; Donato Lacedonia; Mario Malerba; Pasquale Tondo; Piera Soccio; Domenico Loizzi; Maria Pia Foschino Barbaro; Francesco Sollitto Journal: Biomed Res Int Date: 2022-02-21 Impact factor: 3.411
Authors: Giovanna Elisiana Carpagnano; Alessandro Radaeli; Donato Lacedonia; Michele Correale; Giuseppe Carpagnano; Antonio Palmiotti; Maria Pia Foschino Barbaro; Matteo Di Biase; Natale Brunetti; Giulia Scioscia; Mario Malerba Journal: Biomed Res Int Date: 2018-08-26 Impact factor: 3.411