Literature DB >> 27882265

Blood Derived Induced Pluripotent Stem Cells (iPSCs): Benefits, Challenges and the Road Ahead.

Holly N Cukier1,2, Jimmy El Hokayem1, Derek M Dykxhoorn1,3.   

Abstract

Since the creation of induced Pluripotent Stem Cells (iPSCs) ten years ago, hundreds of publications have demonstrated their considerable impact on disease modeling and therapy. In this commentary, we will summarize key milestones, benefits and challenges in the iPSC field. Furthermore, we will highlight blood as an effective and easily accessible source for patient-specific iPSCs derivation in the context of work done in our laboratory and others.

Entities:  

Year:  2016        PMID： 27882265      PMCID： PMC5118044          DOI： 10.4172/2161-0460.1000275

Source DB:  PubMed          Journal:  J Alzheimers Dis Parkinsonism


  28 in total

1.  Derivation of autism spectrum disorder-specific induced pluripotent stem cells from peripheral blood mononuclear cells.

Authors:  Brooke A DeRosa; Jessica M Van Baaren; Gaurav K Dubey; Joycelyn M Lee; Michael L Cuccaro; Jeffery M Vance; Margaret A Pericak-Vance; Derek M Dykxhoorn
Journal:  Neurosci Lett       Date:  2012-03-07       Impact factor: 3.046

2.  Generation of a vascularized and functional human liver from an iPSC-derived organ bud transplant.

Authors:  Takanori Takebe; Ran-Ran Zhang; Hiroyuki Koike; Masaki Kimura; Emi Yoshizawa; Masahiro Enomura; Naoto Koike; Keisuke Sekine; Hideki Taniguchi
Journal:  Nat Protoc       Date:  2014-01-23       Impact factor: 13.491

Review 3.  When rejuvenation is a problem: challenges of modeling late-onset neurodegenerative disease.

Authors:  Elsa Vera; Lorenz Studer
Journal:  Development       Date:  2015-09-15       Impact factor: 6.868

4.  Establishment of induced pluripotent stem cell (iPSC) line from a 75-year old patient with late onset Alzheimer's disease (LOAD).

Authors:  Zsuzsanna Táncos; Eszter Varga; Eszter Kovács; András Dinnyés; Julianna Kobolák
Journal:  Stem Cell Res       Date:  2016-05-24       Impact factor: 2.020

5.  Establishment of PSEN1 mutant induced pluripotent stem cell (iPSC) line from an Alzheimer's disease (AD) female patient.

Authors:  Csilla Nemes; Eszter Varga; Zsuzsanna Táncos; István Bock; Barbara Francz; Julianna Kobolák; András Dinnyés
Journal:  Stem Cell Res       Date:  2016-05-24       Impact factor: 2.020

6.  Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors.

Authors:  Kazutoshi Takahashi; Shinya Yamanaka
Journal:  Cell       Date:  2006-08-10       Impact factor: 41.582

7.  In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state.

Authors:  Marius Wernig; Alexander Meissner; Ruth Foreman; Tobias Brambrink; Manching Ku; Konrad Hochedlinger; Bradley E Bernstein; Rudolf Jaenisch
Journal:  Nature       Date:  2007-06-06       Impact factor: 49.962

8.  Rapid and Efficient Generation of Transgene-Free iPSC from a Small Volume of Cryopreserved Blood.

Authors:  Hongyan Zhou; Hector Martinez; Bruce Sun; Aiqun Li; Matthew Zimmer; Nicholas Katsanis; Erica E Davis; Joanne Kurtzberg; Scott Lipnick; Scott Noggle; Mahendra Rao; Stephen Chang
Journal:  Stem Cell Rev Rep       Date:  2015-08       Impact factor: 5.739

Review 9.  A Comparative View on Human Somatic Cell Sources for iPSC Generation.

Authors:  Stefanie Raab; Moritz Klingenstein; Stefan Liebau; Leonhard Linta
Journal:  Stem Cells Int       Date:  2014-11-06       Impact factor: 5.443

10.  Duplication of TBK1 Stimulates Autophagy in iPSC-derived Retinal Cells from a Patient with Normal Tension Glaucoma.

Authors:  Budd A Tucker; Frances Solivan-Timpe; Ben R Roos; Kristin R Anfinson; Alan L Robin; Luke A Wiley; Robert F Mullins; John H Fingert
Journal:  J Stem Cell Res Ther       Date:  2014-01-25
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  3 in total

1.  Peripheral blood mononuclear cells show prominent gene expression by erythroid progenitors in diseases characterized by heightened erythropoiesis.

Authors:  Xu Zhang; Jihyun Song; Binal N Shah; Sergei Nekhai; Galina Miasnikova; Adelina Sergueeva; Josef T Prchal; Victor R Gordeuk
Journal:  Br J Haematol       Date:  2020-05-12       Impact factor: 6.998

2.  Convergent Pathways in Idiopathic Autism Revealed by Time Course Transcriptomic Analysis of Patient-Derived Neurons.

Authors:  Michael W Nestor; Derek M Dykxhoorn; Brooke A DeRosa; Jimmy El Hokayem; Elena Artimovich; Catherine Garcia-Serje; Andre W Phillips; Derek Van Booven; Jonathan E Nestor; Lily Wang; Michael L Cuccaro; Jeffery M Vance; Margaret A Pericak-Vance; Holly N Cukier
Journal:  Sci Rep       Date:  2018-05-30       Impact factor: 4.379

Review 3.  Platforms for Personalized Polytherapeutics Discovery in COVID-19.

Authors:  Christopher Hopkins; Chidinma Onweni; Victoria Zambito; DeLisa Fairweather; Kathryn McCormick; Hideki Ebihara; Thomas Caulfield; Yu Shrike Zhang; W David Freeman
Journal:  J Mol Biol       Date:  2021-03-20       Impact factor: 6.151
  3 in total

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