Sandra Andersson Kallin1, Eva Lindberg1, Johan Nilsson Sommar2, Apostolos Bossios3, Linda Ekerljung3, Andrei Malinovschi4, Roelinde Middelveld5,6, Christer Janson1. 1. a Department of Medical Sciences : Respiratory, Allergy and Sleep Research, Uppsala University , Uppsala , Sweden. 2. b Occupational and Environmental Medicine, Department of Public Health and Clinical Medicine , Umeå University , Umeå , Sweden. 3. c Department of Internal Medicine and Clinical Nutrition , Krefting Research Centre, Sahlgrenska Academy, University of Gothenburg , Göteborg , Sweden. 4. d Department of Medical Sciences: Clinical Physiology , Uppsala University , Uppsala , Sweden. 5. e The Centre for Allergy Research, Karolinska Institutet , Stockholm , Sweden. 6. f The Institute of Environmental Medicine, Karolinska Institutet , Stockholm , Sweden.
Abstract
OBJECTIVE: Previous studies have found that excessive daytime sleepiness (EDS) is a more common problem in asthmatic subjects than in the general population. The aim of this study was to investigate whether the prevalence of EDS is increased in asthmatic subjects and, if so, to analyse the occurrence of potential risk factors for EDS in asthmatics. METHODS: Cross-sectional epidemiological study. In 2008, a postal questionnaire was sent out to a random sample of 45,000 individuals aged 16-75 years in four Swedish cities. RESULTS: Of the 25,160 persons who participated, 7.3% were defined as having asthma. The prevalence of EDS was significantly higher in asthmatic subjects (42.1% vs. 28.5%, p < 0.001) compared with non-asthmatic subjects. Asthma was an independent risk factor for EDS (adjusted OR 1.29) and the risk of having EDS increased with asthma severity. Risk factors for EDS in subjects with asthma included insomnia (OR, 3.87; 95% CI, 3.10-4.84); chronic rhinosinusitis (OR, 2.00; 95% CI, 1.53-2.62); current smoking (OR, 1.60; 95% CI, 1.15-2.22) and obesity (OR, 1.53; 95% CI, 1.09-2.13). CONCLUSIONS: EDS is a common problem among subjects with asthma. Asthma is an independent risk factor for having EDS. Furthermore, subjects with asthma often have other risk factors for EDS, many of them potentially modifiable.
OBJECTIVE: Previous studies have found that excessive daytime sleepiness (EDS) is a more common problem in asthmatic subjects than in the general population. The aim of this study was to investigate whether the prevalence of EDS is increased in asthmatic subjects and, if so, to analyse the occurrence of potential risk factors for EDS in asthmatics. METHODS: Cross-sectional epidemiological study. In 2008, a postal questionnaire was sent out to a random sample of 45,000 individuals aged 16-75 years in four Swedish cities. RESULTS: Of the 25,160 persons who participated, 7.3% were defined as having asthma. The prevalence of EDS was significantly higher in asthmatic subjects (42.1% vs. 28.5%, p < 0.001) compared with non-asthmatic subjects. Asthma was an independent risk factor for EDS (adjusted OR 1.29) and the risk of having EDS increased with asthma severity. Risk factors for EDS in subjects with asthma included insomnia (OR, 3.87; 95% CI, 3.10-4.84); chronic rhinosinusitis (OR, 2.00; 95% CI, 1.53-2.62); current smoking (OR, 1.60; 95% CI, 1.15-2.22) and obesity (OR, 1.53; 95% CI, 1.09-2.13). CONCLUSIONS: EDS is a common problem among subjects with asthma. Asthma is an independent risk factor for having EDS. Furthermore, subjects with asthma often have other risk factors for EDS, many of them potentially modifiable.
Authors: Lindsey J Wanberg; Rebecca E Rottapel; Michelle L Reid; Suzanne M Bertisch; Morgan Bron; Vishesh K Kapur; Shay Bujanover; Zinta Harrington; Jessie P Bakker; Sogol Javaheri; Mark Hanson; Kathleen Figetakis; Kathy Page; Sherry Hanes; Kathleen F Villa; Susan Redline Journal: J Clin Sleep Med Date: 2021-12-01 Impact factor: 4.062
Authors: Viiu Blöndal; Andrei Malinovschi; Fredrik Sundbom; Anna James; Roelinde Middelveld; Karl A Franklin; Bo Lundbäck; Christer Janson Journal: Clin Exp Allergy Date: 2020-10-25 Impact factor: 5.018