Literature DB >> 27879984

No End in Sight: Benzodiazepine Use in Older Adults in the United States.

Donovan T Maust1,2,3, Helen C Kales1,2,3, Ilse R Wiechers4,5, Frederic C Blow1,2,3, Mark Olfson6,7.   

Abstract

OBJECTIVES: To establish the rate of new and continuation of benzodiazepine use in older adults seen by nonpsychiatrist physicians and to identify subpopulations at risk of new and continuation benzodiazepine use.
DESIGN: Cross-sectional analysis.
SETTING: National Ambulatory Medical Care Survey (2007-10). PARTICIPANTS: Adults visiting office-based nonpsychiatrist physicians (n = 98,818) who were prescribed a benzodiazepine (new or continuation). MEASUREMENTS: Percentage of benzodiazepine visits of all outpatient encounters according to patient age and corresponding annual visit rate per 1,000 population. Analysis was then limited to adults aged 65 and older, demographic, clinical, and visits characteristics were used to compare visits of benzodiazepine users with those of nonusers and visits of continuation users with those of new users.
RESULTS: The overall proportion of benzodiazepine visits ranged from 3.2% (95% confidence interval (CI) = 2.7-3.7) of those aged 18 to 34 to 6.6% (95% CI = 5.8-7.6) of those aged 80 and older, and the proportion of continuation visits increased with age, rising to 90.2% (95% CI = 86.2-93.1) of those aged 80 and older. The population-based visit rate ranged from 61.7 (95% CI = 50.7-72.7) per 1,000 persons in the youngest adults to 463.7 (95% CI = 385.4-542.0) in those aged 80 and older. Only 16.0% (95% CI = 13.5-18.8) of continuation users had any mental health diagnosis. Of all benzodiazepine users, fewer than 1% (95% CI = .4-1.8) were provided or referred to psychotherapy, and 10.0% (95% CI = 7. 2-13.3) were also prescribed an opioid.
CONCLUSION: In the United States, few older adult benzodiazepine users receive a clinical mental health diagnosis, and almost none are provided or referred to psychotherapy. Prescribing to older adults continues despite decades of evidence documenting safety concerns, effective alternative treatments, and effective methods for tapering even chronic users.
© 2016, Copyright the Authors Journal compilation © 2016, The American Geriatrics Society.

Entities:  

Keywords:  anxiety; benzodiazepine; insomnia; psychotropic

Mesh:

Substances:

Year:  2016        PMID: 27879984      PMCID: PMC5173408          DOI: 10.1111/jgs.14379

Source DB:  PubMed          Journal:  J Am Geriatr Soc        ISSN: 0002-8614            Impact factor:   5.562


  37 in total

1.  1979 summary: National Ambulatory Medical Care Survey.

Authors:  T McLemore
Journal:  Adv Data       Date:  1981-03-02

2.  American Geriatrics Society 2015 Updated Beers Criteria for Potentially Inappropriate Medication Use in Older Adults.

Authors: 
Journal:  J Am Geriatr Soc       Date:  2015-10-08       Impact factor: 5.562

3.  Pharmaceutical overdose deaths, United States, 2010.

Authors:  Christopher M Jones; Karin A Mack; Leonard J Paulozzi
Journal:  JAMA       Date:  2013-02-20       Impact factor: 56.272

4.  Cognitive Behavioral Therapy for Insomnia Comorbid With Psychiatric and Medical Conditions: A Meta-analysis.

Authors:  Jade Q Wu; Erica R Appleman; Robert D Salazar; Jason C Ong
Journal:  JAMA Intern Med       Date:  2015-09       Impact factor: 21.873

5.  Long-term continuous use of benzodiazepines by older adults in Quebec: prevalence, incidence and risk factors.

Authors:  M Egan; Y Moride; C Wolfson; J Monette
Journal:  J Am Geriatr Soc       Date:  2000-07       Impact factor: 5.562

6.  Opioid analgesics and the risk of fractures in older adults with arthritis.

Authors:  Matthew Miller; Til Stürmer; Deborah Azrael; Raisa Levin; Daniel H Solomon
Journal:  J Am Geriatr Soc       Date:  2011-03       Impact factor: 5.562

Review 7.  Meta-analysis of the impact of 9 medication classes on falls in elderly persons.

Authors:  John C Woolcott; Kathryn J Richardson; Matthew O Wiens; Bhavini Patel; Judith Marin; Karim M Khan; Carlo A Marra
Journal:  Arch Intern Med       Date:  2009-11-23

8.  Short-term psychodynamic psychotherapy and cognitive-behavioral therapy in generalized anxiety disorder: a randomized, controlled trial.

Authors:  Falk Leichsenring; Simone Salzer; Ulrich Jaeger; Horst Kächele; Reinhard Kreische; Frank Leweke; Ulrich Rüger; Christel Winkelbach; Eric Leibing
Journal:  Am J Psychiatry       Date:  2009-07-01       Impact factor: 18.112

9.  Discontinuation of benzodiazepines among older insomniac adults treated with cognitive-behavioural therapy combined with gradual tapering: a randomized trial.

Authors:  Lucie Baillargeon; Philippe Landreville; René Verreault; Jean-Pierre Beauchemin; Jean-Pierre Grégoire; Charles M Morin
Journal:  CMAJ       Date:  2003-11-11       Impact factor: 8.262

Review 10.  Interventions for reducing benzodiazepine use in older people: meta-analysis of randomised controlled trials.

Authors:  Rebecca L Gould; Mark C Coulson; Natasha Patel; Elizabeth Highton-Williamson; Robert J Howard
Journal:  Br J Psychiatry       Date:  2014-02       Impact factor: 9.319

View more
  18 in total

Review 1.  Deprescribing Benzodiazepines in Older Patients: Impact of Interventions Targeting Physicians, Pharmacists, and Patients.

Authors:  Brendan J Ng; David G Le Couteur; Sarah N Hilmer
Journal:  Drugs Aging       Date:  2018-06       Impact factor: 3.923

2.  Epidemic Use of Benzodiazepines among Older Adults in Israel: Epidemiology and Leverage Points for Improvement.

Authors:  Michael A Steinman; Marcelo Low; Ran D Balicer; Efrat Shadmi
Journal:  J Gen Intern Med       Date:  2017-05-03       Impact factor: 5.128

3.  Benzodiazepine Use and Misuse Among Adults in the United States.

Authors:  Donovan T Maust; Lewei A Lin; Frederic C Blow
Journal:  Psychiatr Serv       Date:  2018-12-17       Impact factor: 3.084

4.  Benzodiazepine Use in Older Adults in the United States, Ontario, and Australia from 2010 to 2016.

Authors:  Jonathan Brett; Donovan T Maust; Zach Bouck; Rosalinda V Ignacio; Graham Mecredy; Eve A Kerr; Sacha Bhatia; Adam G Elshaug; Sallie A Pearson
Journal:  J Am Geriatr Soc       Date:  2018-02-12       Impact factor: 5.562

5.  Discontinuation of Chronic Benzodiazepine Use Among Adults in the United States.

Authors:  Lauren B Gerlach; Julie Strominger; Hyungjin Myra Kim; Donovan T Maust
Journal:  J Gen Intern Med       Date:  2019-06-25       Impact factor: 5.128

6.  As-Needed Prescribing and Administration of Psychotropic Medications in Assisted Living: A 7-State Study.

Authors:  Paula Carder; Sheryl Zimmerman; Christopher J Wretman; John S Preisser; Sarah Dys; Philip D Sloane
Journal:  J Am Med Dir Assoc       Date:  2021-12-14       Impact factor: 7.802

7.  County and Physician Variation in Benzodiazepine Prescribing to Medicare Beneficiaries by Primary Care Physicians in the USA.

Authors:  Donovan T Maust; Lewei A Lin; Frederic C Blow; Steven C Marcus
Journal:  J Gen Intern Med       Date:  2018-09-24       Impact factor: 5.128

Review 8.  Prescription Benzodiazepine Use Among Older Adults: A Critical Review.

Authors:  Lauren B Gerlach; Ilse R Wiechers; Donovan T Maust
Journal:  Harv Rev Psychiatry       Date:  2018 Sep/Oct       Impact factor: 3.732

9.  Trends in benzodiazepine receptor agonists use and associated factors in the Belgian general older population: analysis of the Belgian health interview survey data.

Authors:  Catherine Pétein; Anne Spinewine; Séverine Henrard
Journal:  Ther Adv Psychopharmacol       Date:  2021-05-25

10.  Prescription of potentially inappropriate medications among older people with intellectual disability: a register study.

Authors:  Anna Axmon; Magnus Sandberg; Gerd Ahlström; Patrik Midlöv
Journal:  BMC Pharmacol Toxicol       Date:  2017-10-25       Impact factor: 2.483

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.