Literature DB >> 34919835

As-Needed Prescribing and Administration of Psychotropic Medications in Assisted Living: A 7-State Study.

Paula Carder1, Sheryl Zimmerman2, Christopher J Wretman3, John S Preisser4, Sarah Dys5, Philip D Sloane6.   

Abstract

OBJECTIVES: Psychotropic medications administered on an as-needed basis, often designated as pro re nata (or PRN, hereafter as-needed), can alleviate acute symptoms and facilitate deprescribing, although as-needed use is associated with negative outcomes such as polypharmacy and drug interactions. The aim of this study was to examine the extent to which PRN psychotropic medications are prescribed and administered to assisted living (AL) residents, overall and in relation to resident- and community-level characteristics.
DESIGN: Cross-sectional study. SETTING AND PARTICIPANTS: All AL residents and select staff in 250 AL communities in 7 states.
METHODS: Data regarding prescribing and administration of 5 types of PRN psychotropic medications in the prior 7 days (antipsychotics, mood stabilizers and antiepileptics, antidepressants, anxiolytics/hypnotics, and cognitive enhancers) were abstracted and compared across resident and community characteristics.
RESULTS: Prescribing of PRN psychotropics in AL is low (10.3%). Of prescribed PRN medications, 2.5% of residents were administered a PRN and 8% had PRN that was not administered in the previous 7 days. Anxiolytics were administered PRN more commonly compared with antipsychotics (2.0% vs 0.2%). Of all PRN psychotropic prescriptions (n = 1039), 70.5% had a written indication describing the reason for administration. Among PRN medications administered (n = 242), the proportion with an indication was lower (62.0%). PRN psychotropic medication prescribing was higher among residents with dementia and a psychiatric diagnosis, and in larger AL communities and those with a higher proportion of dementia care beds. CONCLUSIONS AND IMPLICATIONS: The prescribing and administration of PRN psychotropic medications in AL is relatively rare, although more common among residents with dementia. Emerging psychotropic medication policies should be expanded to address mental health care, anxiolytic/hypnotic use for residents living with dementia, PRN prescribing in chart review, and the use of detailed indications for PRN use, especially when medications are administered by unlicensed care staff.
Copyright © 2021 AMDA – The Society for Post-Acute and Long-Term Care Medicine. Published by Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Assisted living; antipsychotic; dementia; pro re nata; psychotropic

Mesh:

Substances:

Year:  2021        PMID: 34919835      PMCID: PMC9177506          DOI: 10.1016/j.jamda.2021.11.009

Source DB:  PubMed          Journal:  J Am Med Dir Assoc        ISSN: 1525-8610            Impact factor:   7.802


  43 in total

1.  Addressing Antipsychotic Use in Assisted Living Residents with Dementia.

Authors:  Sheryl Zimmerman; Kezia Scales; Britney Wiggins; Lauren W Cohen; Philip D Sloane
Journal:  J Am Geriatr Soc       Date:  2015-09       Impact factor: 5.562

Review 2.  Management of neuropsychiatric symptoms of dementia in clinical settings: recommendations from a multidisciplinary expert panel.

Authors:  Helen C Kales; Laura N Gitlin; Constantine G Lyketsos
Journal:  J Am Geriatr Soc       Date:  2014-03-17       Impact factor: 5.562

3.  Stage-specific prevalence of behavioral symptoms in Alzheimer's disease in a multi-ethnic community sample.

Authors:  J C Chen; S Borson; J M Scanlan
Journal:  Am J Geriatr Psychiatry       Date:  2000       Impact factor: 4.105

4.  Frequency of and factors related to pro re nata (PRN) medication use in aged care services.

Authors:  Jacquelina Stasinopoulos; J Simon Bell; Taliesin E Ryan-Atwood; Edwin C K Tan; Jenni Ilomäki; Tina Cooper; Leonie Robson; Janet K Sluggett
Journal:  Res Social Adm Pharm       Date:  2017-11-07

5.  Dementia prevalence and care in assisted living.

Authors:  Sheryl Zimmerman; Philip D Sloane; David Reed
Journal:  Health Aff (Millwood)       Date:  2014-04       Impact factor: 6.301

6.  When Less is More, but Still Not Enough: Why Focusing on Limiting Antipsychotics in People With Dementia Is the Wrong Policy Imperative.

Authors:  Helen C Kales; Laura N Gitlin; Constantine G Lyketsos
Journal:  J Am Med Dir Assoc       Date:  2019-08-06       Impact factor: 4.669

7.  Reducing Off-Label Antipsychotic Use in Older Adults: Time to Look Beyond the Doors of Nursing Homes.

Authors:  Kate L Lapane
Journal:  J Am Geriatr Soc       Date:  2018-01-22       Impact factor: 5.562

8.  Nursing home physicians' knowledge of and attitudes toward nonpharmacological interventions for treatment of behavioral disturbances associated with dementia.

Authors:  Jiska Cohen-Mansfield; Barbara Jensen
Journal:  J Am Med Dir Assoc       Date:  2008-09       Impact factor: 4.669

9.  Prevalence of, and Resident and Facility Characteristics Associated With Antipsychotic Use in Assisted Living vs. Long-Term Care Facilities: A Cross-Sectional Analysis from Alberta, Canada.

Authors:  Kathryn J Stock; Joseph E Amuah; Kate L Lapane; David B Hogan; Colleen J Maxwell
Journal:  Drugs Aging       Date:  2017-01       Impact factor: 3.923

10.  Association of Mental Health Disorders With Health Care Spending in the Medicare Population.

Authors:  Jose F Figueroa; Jessica Phelan; E John Orav; Vikram Patel; Ashish K Jha
Journal:  JAMA Netw Open       Date:  2020-03-02
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