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Literature DB >> 27872952

Molecular Phylogenetics and the Perennial Problem of Homology.

Abstract

The concept of homology has a long history, during much of which the issue has been how to reconcile similarity and common descent when these are not coextensive. Although thinking molecular phylogeneticists have learned not to say "percent homology," the problems are deeper than that and unresolved.

Keywords: Homology; Molecular phylogenetics; Philosophy of biology

Mesh：

Year: 2016 PMID： 27872952 DOI： 10.1007/s00239-016-9766-4

Source DB: PubMed Journal: J Mol Evol ISSN： 0022-2844 Impact factor: 2.395

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References

33 in total

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Authors: W M Fitch; E Margoliash
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Molecular Phylogenetics and the Perennial Problem of Homology.

1. Understanding hierarchical protein evolution from first principles.

Review 2. Protein families and their evolution-a structural perspective.

3. Speculations on the early course of evolution.

4. The formation of the theory of homology in biological sciences.

5. Distinguishing homologous from analogous proteins.

Review 6. Construction of phylogenetic trees.

Review 7. Convergent evolution: the need to be explicit.

8. The Defensins Consist of Two Independent, Convergent Protein Superfamilies.

9. An empirical test of convergent evolution in rhodopsins.

10. Helical antifreeze proteins have independently evolved in fishes on four occasions.