Literature DB >> 27871006

Evaluating the use of friend or family controls in epidemiologic case-control studies.

Charlie Zhong1, Myles Cockburn2, Wendy Cozen2, Jenna Voutsinas1, James V Lacey1, Jianning Luo1, Jane Sullivan-Halley1, Leslie Bernstein1, Sophia S Wang3.   

Abstract

BACKGROUND: Traditional methodologies for identifying and recruiting controls in epidemiologic case-control studies, such as random digit dialing or neighborhood walk, suffer from declining response rates. Here, we revisit the feasibility and comparability of using alternative sources of controls, specifically friend and family controls.
METHODS: We recruited from a recently completed case-control study of non-Hodgkin lymphoma (NHL) among women in Los Angeles County where controls from the parent study were ascertained by neighborhood walk. We calculated participation rates and compared questionnaire responses between the friend/family controls and the original matched controls from the parent study.
RESULTS: Of the 182 NHL case patients contacted, 111 (61%) agreed to participate in our feasibility study. 70 (63%) provided contact information for potential friend and/or family member controls. We were able to successfully contact and recruit a friend/family member for 92% of the case patients. This represented 46 friend controls and 54 family controls. Family controls significantly differed from original matched controls by sex and household income. Other characteristics were similar between friend controls and the original study's neighborhood controls.
CONCLUSION: The apparent comparability of neighborhood controls to friend and family controls among respondents in this study suggests that these alternative methods of control identification can serve as a complementary source of eligible controls in epidemiologic case-control studies.
Copyright © 2016 The Authors. Published by Elsevier Ltd.. All rights reserved.

Entities:  

Keywords:  Case-control studies; Epidemiologic methods; Non-Hodgkin lymphoma

Mesh:

Year:  2016        PMID: 27871006      PMCID: PMC6252092          DOI: 10.1016/j.canep.2016.10.007

Source DB:  PubMed          Journal:  Cancer Epidemiol        ISSN: 1877-7821            Impact factor:   2.890


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