Literature DB >> 27864206

Educational strategies to enable expansion of pharmacogenomics-based care.

Kristin Wiisanen Weitzel1,2, Christina L Aquilante3, Samuel Johnson4, David F Kisor5, Philip E Empey6.   

Abstract

PURPOSE: The current state of pharmacogenomics education for pharmacy students and practitioners is discussed, and resources and strategies to address persistent challenges in this area are reviewed.
SUMMARY: Consensus-based pharmacist competencies and guidelines have been published to guide pharmacogenomics knowledge attainment and application in clinical practice. Pharmacogenomics education is integrated into various pharmacy school courses and, increasingly, into Pharm.D. curricula in the form of required standalone courses. Continuing-education programs and a limited number of postgraduate training opportunities are available to practicing pharmacists. For colleges and schools of pharmacy, identifying the optimal structure and content of pharmacogenomics education remains a challenge; insufficient numbers of faculty members with pharmacogenomics expertise and the inadequate availability of practice settings for experiential education are other limiting factors. Strategies for overcoming those challenges include providing early exposure to pharmacogenomics through foundational courses and incorporating pharmacogenomics into practice-based therapeutics courses and introductory and advanced pharmacy practice experiences. For practitioner education, online resources, clinical decision support-based tools, and certificate programs can be used to supplement structured postgraduate training in pharmacogenomics. Recently published data indicate successful use of "shared curricula" and participatory education models involving opportunities for learners to undergo personal genomic testing.
CONCLUSION: The pharmacy profession has taken a leadership role in expanding student and practitioner education to meet the demand for increased pharmacist involvement in precision medicine initiatives. Effective approaches to teaching pharmacogenomics knowledge and driving its appropriate application in clinical practice are increasingly available.
Copyright © 2016 by the American Society of Health-System Pharmacists, Inc. All rights reserved.

Entities:  

Keywords:  continuing; education; genomics/education; pharmacists; pharmacogenetics/education; pharmacogenetics/trends; pharmacy; precision medicine; schools

Mesh:

Year:  2016        PMID: 27864206      PMCID: PMC5665396          DOI: 10.2146/ajhp160104

Source DB:  PubMed          Journal:  Am J Health Syst Pharm        ISSN: 1079-2082            Impact factor:   2.637


  61 in total

1.  Establishment of the genetic/genomic competency center for education.

Authors:  Kathleen A Calzone; Bonnie Jerome-D'Emilia; Jean Jenkins; Constance Goldgar; Michael Rackover; John Jackson; Ye Chen; John Voss; W Gregory Feero
Journal:  J Nurs Scholarsh       Date:  2011-08-26       Impact factor: 3.176

2.  Educating future providers of personalized medicine.

Authors:  Sara H Katsanis; Jennifer R Dungan; Catherine L Gilliss; Geoffrey A Ginsburg
Journal:  N C Med J       Date:  2013 Nov-Dec

3.  A genotyping exercise for pharmacogenetics in pharmacy practice.

Authors:  Daren L Knoell; Jeffrey S Johnston; Shengying Bao; Katherine A Kelley
Journal:  Am J Pharm Educ       Date:  2009-05-27       Impact factor: 2.047

4.  Pharmacogenomics in the curricula of colleges and schools of pharmacy in the United States.

Authors:  John E Murphy; James S Green; Laura A Adams; Robert B Squire; Grace M Kuo; Alan McKay
Journal:  Am J Pharm Educ       Date:  2010-02-10       Impact factor: 2.047

5.  Bringing clinical pharmacogenomics information to pharmacists: A qualitative study of information needs and resource requirements.

Authors:  Katrina M Romagnoli; Richard D Boyce; Philip E Empey; Solomon Adams; Harry Hochheiser
Journal:  Int J Med Inform       Date:  2015-11-30       Impact factor: 4.046

6.  Deterioration of blood pressure control after discontinuation of a physician-pharmacist collaborative intervention.

Authors:  Barry L Carter; William R Doucette; Carrie L Franciscus; Gail Ardery; Karen M Kluesner; Elizabeth A Chrischilles
Journal:  Pharmacotherapy       Date:  2010-03       Impact factor: 4.705

Review 7.  Pharmacogenomics knowledge for personalized medicine.

Authors:  M Whirl-Carrillo; E M McDonagh; J M Hebert; L Gong; K Sangkuhl; C F Thorn; R B Altman; T E Klein
Journal:  Clin Pharmacol Ther       Date:  2012-10       Impact factor: 6.875

Review 8.  Clinical genomics in the world of the electronic health record.

Authors:  Keith Marsolo; S Andrew Spooner
Journal:  Genet Med       Date:  2013-07-11       Impact factor: 8.822

9.  Personal genome testing in medical education: student experiences with genotyping in the classroom.

Authors:  Simone Lucia Vernez; Keyan Salari; Kelly E Ormond; Sandra Soo-Jin Lee
Journal:  Genome Med       Date:  2013-03-19       Impact factor: 11.117

10.  Incorporation of pharmacogenomics into routine clinical practice: the Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline development process.

Authors:  Kelly E Caudle; Teri E Klein; James M Hoffman; Daniel J Muller; Michelle Whirl-Carrillo; Li Gong; Ellen M McDonagh; Katrin Sangkuhl; Caroline F Thorn; Matthias Schwab; Jose A G Agundez; Robert R Freimuth; Vojtech Huser; Ming Ta Michael Lee; Otito F Iwuchukwu; Kristine R Crews; Stuart A Scott; Mia Wadelius; Jesse J Swen; Rachel F Tyndale; C Michael Stein; Dan Roden; Mary V Relling; Marc S Williams; Samuel G Johnson
Journal:  Curr Drug Metab       Date:  2014-02       Impact factor: 3.731

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  23 in total

1.  Clinical Pharmacogenomics: Applications in Nephrology.

Authors:  Solomon M Adams; Karryn R Crisamore; Philip E Empey
Journal:  Clin J Am Soc Nephrol       Date:  2018-05-23       Impact factor: 8.237

2.  Pharmacy students' attitudes and perceptions toward pharmacogenomics education.

Authors:  Shanice Coriolan; Nimota Arikawe; Arden Moscati; Lisheng Zhou; Stephanie Dym; Seda Donmez; Adinoyi Garba; Sasha Falbaum; Zvi Loewy; Melinda Lull; Maha Saad; Jane Shtaynberg; Aniwaa Owusu Obeng
Journal:  Am J Health Syst Pharm       Date:  2019-05-17       Impact factor: 2.637

3.  Pharmacogenomics courses in pharmacy school curricula.

Authors:  Susanne B Haga; Jivan Moaddeb
Journal:  Pharmacogenomics       Date:  2019-06       Impact factor: 2.533

4.  Aligning the AACP Strategic Engagement Agenda with Key Federal Priorities in Health: Report of the 2016-17 Argus Commission.

Authors:  Brian Crabtree; J Lyle Bootman; Cynthia J Boyle; Patricia Chase; Peggy Piascik; Lucinda L Maine
Journal:  Am J Pharm Educ       Date:  2017-10       Impact factor: 2.047

5.  An Effective Approach to Teaching Pharmacogenomics in the First Year of Pharmacy Curriculum.

Authors:  Marina Gálvez-Peralta; Grazyna D Szklarz; Werner J Geldenhuys; Paul R Lockman
Journal:  Am J Pharm Educ       Date:  2018-10       Impact factor: 2.047

6.  The Role of the Pediatric Pharmacist in Precision Medicine and Clinical Pharmacogenomics for Children.

Authors:  Jacob T Brown; David Gregornik; Mary Jayne Kennedy
Journal:  J Pediatr Pharmacol Ther       Date:  2018 Nov-Dec

7.  Patient characteristics, experiences and perceived value of pharmacogenetic testing from a single testing laboratory.

Authors:  Susanne B Haga; Yiling Liu
Journal:  Pharmacogenomics       Date:  2019-06       Impact factor: 2.533

8.  Integrating pharmacogenetic testing into primary care.

Authors:  Susanne B Haga
Journal:  Expert Rev Precis Med Drug Dev       Date:  2017-11-03

9.  Multisite Investigation of Strategies for the Implementation of CYP2C19 Genotype-Guided Antiplatelet Therapy.

Authors:  Philip E Empey; James M Stevenson; Sony Tuteja; Kristin W Weitzel; Dominick J Angiolillo; Amber L Beitelshees; James C Coons; Julio D Duarte; Francesco Franchi; Linda J B Jeng; Julie A Johnson; Rolf P Kreutz; Nita A Limdi; Kristin A Maloney; Aniwaa Owusu Obeng; Josh F Peterson; Natasha Petry; Victoria M Pratt; Fabiana Rollini; Stuart A Scott; Todd C Skaar; Mark R Vesely; George A Stouffer; Russell A Wilke; Larisa H Cavallari; Craig R Lee
Journal:  Clin Pharmacol Ther       Date:  2018-01-30       Impact factor: 6.875

10.  Providers' perspectives on the clinical utility of pharmacogenomic testing in pediatric patients.

Authors:  Ina Liko; Yee Ming Lee; Danielle L Stutzman; Allison B Blackmer; Kimberly M Deininger; Ann M Reynolds; Christina L Aquilante
Journal:  Pharmacogenomics       Date:  2021-03-04       Impact factor: 2.533

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