Bei Zhang1,2, Alan C Seifert1,2,3, Joo-Won Kim1,2,3, Joseph Borrello1,2,3, Junqian Xu1,2,3,4. 1. Translational and Molecular Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA. 2. Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, New York, USA. 3. Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA. 4. Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Abstract
PURPOSE: Increased signal-to-noise ratio and blood oxygenation level-dependent sensitivity at 7 Tesla (T) have the potential to enable high-resolution imaging of the human cervical spinal cord and brainstem. We propose a new two-panel radiofrequency coil design for these regions to fully exploit the advantages of ultra-high field. METHODS: A two-panel array, containing four transmit/receive and 18 receive-only elements fully encircling the head and neck, was constructed following simulations demonstrating the B1+ and specific absorption rate (SAR) benefits of two-panel over one-panel arrays. This array was compared with a previously reported posterior-only array and tested for safety using a phantom. Its anatomical, functional, and diffusion MRI performance was demonstrated in vivo. RESULTS: The two-panel array produced more uniform B1+ across the brainstem and cervical spinal cord without compromising SAR, and achieved 70% greater receive sensitivity than the posterior-only array. The two-panel design enabled acceleration of R = 2 × 2 in two dimensions or R = 3 in a single dimension. High quality in vivo anatomical, functional, and diffusion images of the human cervical spinal cord and brainstem were acquired. CONCLUSION: We have designed and constructed a wrap-around coil array with excellent performance for cervical spinal cord and brainstem MRI at 7T, which enables simultaneous human cervical spinal cord and brainstem functional MRI. Magn Reson Med 78:1623-1634, 2017.
PURPOSE: Increased signal-to-noise ratio and blood oxygenation level-dependent sensitivity at 7 Tesla (T) have the potential to enable high-resolution imaging of the human cervical spinal cord and brainstem. We propose a new two-panel radiofrequency coil design for these regions to fully exploit the advantages of ultra-high field. METHODS: A two-panel array, containing four transmit/receive and 18 receive-only elements fully encircling the head and neck, was constructed following simulations demonstrating the B1+ and specific absorption rate (SAR) benefits of two-panel over one-panel arrays. This array was compared with a previously reported posterior-only array and tested for safety using a phantom. Its anatomical, functional, and diffusion MRI performance was demonstrated in vivo. RESULTS: The two-panel array produced more uniform B1+ across the brainstem and cervical spinal cord without compromising SAR, and achieved 70% greater receive sensitivity than the posterior-only array. The two-panel design enabled acceleration of R = 2 × 2 in two dimensions or R = 3 in a single dimension. High quality in vivo anatomical, functional, and diffusion images of the human cervical spinal cord and brainstem were acquired. CONCLUSION: We have designed and constructed a wrap-around coil array with excellent performance for cervical spinal cord and brainstem MRI at 7T, which enables simultaneous human cervical spinal cord and brainstem functional MRI. Magn Reson Med 78:1623-1634, 2017.
Authors: Bei Zhang; Gregor Adriany; Lance Delabarre; Jerahmie Radder; Russell Lagore; Brian Rutt; Qing X Yang; Kamil Ugurbil; Riccardo Lattanzi Journal: Magn Reson Med Date: 2021-01-19 Impact factor: 3.737
Authors: Hamed Dehghani; Mohammad Ali Oghabian; Seyed Amir Hosein Batouli; Jalil Arab Kheradmand; Ali Khatibi Journal: Basic Clin Neurosci Date: 2020-11-01