Literature DB >> 27853818

Statistics of topological RNA structures.

Thomas J X Li1, Christian M Reidys2.   

Abstract

In this paper we study properties of topological RNA structures, i.e. RNA contact structures with cross-serial interactions that are filtered by their topological genus. RNA secondary structures within this framework are topological structures having genus zero. We derive a new bivariate generating function whose singular expansion allows us to analyze the distributions of arcs, stacks, hairpin- , interior- and multi-loops. We then extend this analysis to H-type pseudoknots, kissing hairpins as well as 3-knots and compute their respective expectation values. Finally we discuss our results and put them into context with data obtained by uniform sampling structures of fixed genus.

Keywords:  Fatgraph; Generating function; Genus; Loop; Pseudoknot; RNA structure; Singularity analysis

Mesh:

Substances:

Year:  2016        PMID: 27853818     DOI: 10.1007/s00285-016-1078-1

Source DB:  PubMed          Journal:  J Math Biol        ISSN: 0303-6812            Impact factor:   2.259


  22 in total

1.  Topological classification of RNA structures.

Authors:  Michael Bon; Graziano Vernizzi; Henri Orland; A Zee
Journal:  J Mol Biol       Date:  2008-04-18       Impact factor: 5.469

2.  Combinatorial analysis of interacting RNA molecules.

Authors:  Thomas J X Li; Christian M Reidys
Journal:  Math Biosci       Date:  2011-06-12       Impact factor: 2.144

3.  Topology and prediction of RNA pseudoknots.

Authors:  Christian M Reidys; Fenix W D Huang; Jørgen E Andersen; Robert C Penner; Peter F Stadler; Markus E Nebel
Journal:  Bioinformatics       Date:  2011-02-17       Impact factor: 6.937

4.  Topological language for RNA.

Authors:  Fenix W D Huang; Christian M Reidys
Journal:  Math Biosci       Date:  2016-10-20       Impact factor: 2.144

5.  The topological filtration of γ-structures.

Authors:  Thomas J X Li; Christian M Reidys
Journal:  Math Biosci       Date:  2012-09-26       Impact factor: 2.144

6.  Algebraic and combinatorial properties of common RNA pseudoknot classes with applications.

Authors:  Markus E Nebel; Frank Weinberg
Journal:  J Comput Biol       Date:  2012-10       Impact factor: 1.479

7.  RNA Secondary Structures Having a Compatible Sequence of Certain Nucleotide Ratios.

Authors:  Christopher L Barrett; Thomas J X Li; Christian M Reidys
Journal:  J Comput Biol       Date:  2016-06-20       Impact factor: 1.479

8.  A comparison of thermodynamic foldings with comparatively derived structures of 16S and 16S-like rRNAs.

Authors:  D A Konings; R R Gutell
Journal:  RNA       Date:  1995-08       Impact factor: 4.942

9.  An alcohol dehydrogenase ribozyme.

Authors:  Shinya Tsukiji; Swetansu B Pattnaik; Hiroaki Suga
Journal:  Nat Struct Biol       Date:  2003-08-10

10.  Pseudoknots: RNA structures with diverse functions.

Authors:  David W Staple; Samuel E Butcher
Journal:  PLoS Biol       Date:  2005-06-14       Impact factor: 8.029

View more
  1 in total

1.  The block spectrum of RNA pseudoknot structures.

Authors:  Thomas J X Li; Christie S Burris; Christian M Reidys
Journal:  J Math Biol       Date:  2019-06-06       Impact factor: 2.259

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.