Literature DB >> 2784977

Effect of prolonged sedation with propofol on serum triglyceride and cholesterol concentrations.

M Gottardis1, K S Khünl-Brady, W Koller, G Sigl, J M Hackl.   

Abstract

We compared changes in serum lipid concentrations in ICU patients receiving a 3-day continuous infusion of propofol with those in patients receiving conventional sedation. No adverse effects were observed and the serum lipid concentrations were not significantly influenced by propofol. It is concluded that propofol might be a suitable agent for long-term sedation in the ICU, although serum lipid concentrations should be monitored throughout its administration.

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Year:  1989        PMID： 2784977     DOI： 10.1093/bja/62.4.393

Source DB:  PubMed          Journal:  Br J Anaesth        ISSN： 0007-0912            Impact factor:   9.166


  14 in total

Review 1.  Sedation and analgesia in paediatric intensive care units: a guide to drug selection and use.

Authors:  J D Tobias
Journal:  Paediatr Drugs       Date:  1999 Apr-Jun       Impact factor: 3.022

Review 2.  Acute pancreatitis after single-dose exposure to propofol: a case report and review of literature.

Authors:  Qaiser Jawaid; Michael E Presti; Brent A Neuschwander-Tetri; Frank R Burton
Journal:  Dig Dis Sci       Date:  2002-03       Impact factor: 3.199

3.  The effect on serum lipid concentrations of a prolonged infusion of propofol--hypertriglyceridaemia associated with propofol administration.

Authors:  J M Eddleston; M P Shelly
Journal:  Intensive Care Med       Date:  1991       Impact factor: 17.440

Review 4.  Sedation for critically ill or injured adults in the intensive care unit: a shifting paradigm.

Authors:  Derek J Roberts; Babar Haroon; Richard I Hall
Journal:  Drugs       Date:  2012-10-01       Impact factor: 9.546

5.  Pharmacokinetics, induction of anaesthesia and safety characteristics of propofol 6% SAZN vs propofol 1% SAZN and Diprivan-10 after bolus injection.

Authors:  C A Knibbe; H J Voortman; L P Aarts; P F Kuks; R Lange; H J Langemeijer; M Danhof
Journal:  Br J Clin Pharmacol       Date:  1999-06       Impact factor: 4.335

6.  Pilot study in humans on the pharmacokinetics and safety of propofol 6% SAZN.

Authors:  C A Knibbe; V S Koster; L P Aarts; H J Langemeijer; M Danhof
Journal:  Pharm World Sci       Date:  1999-10

Review 7.  Propofol for sedation in neuro-intensive care.

Authors:  Michael P Hutchens; Stavros Memtsoudis; Nicholas Sadovnikoff
Journal:  Neurocrit Care       Date:  2006       Impact factor: 3.210

Review 8.  Propofol. An overview of its pharmacology and a review of its clinical efficacy in intensive care sedation.

Authors:  B Fulton; E M Sorkin
Journal:  Drugs       Date:  1995-10       Impact factor: 9.546

9.  The use of propofol for sedation of critically ill patients undergoing haemodiafiltration.

Authors:  J M Eddleston; B J Pollard; J F Blades; B Doran
Journal:  Intensive Care Med       Date:  1995-04       Impact factor: 17.440

Review 10.  Clinical review: severe asthma.

Authors:  Spyros Papiris; Anastasia Kotanidou; Katerina Malagari; Charis Roussos
Journal:  Crit Care       Date:  2001-11-22       Impact factor: 9.097
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