| Literature DB >> 27842888 |
Xiaolan Deng1, Yusuke Nakamura2.
Abstract
With the accelerating progress in basic and clinical cancer research, a huge body of new discoveries and powerful technologies has allowed us to implement a 'Cancer Precision Medicine (CPM)' system for cancer patients. The CPM system covers a wide range of cancer management including cancer screening, monitoring of relapse/recurrence, selection/prediction of effective drugs/treatments, and personalized immunotherapy. In this system individual cancer patients expect to receive personalized care: an appropriate dose of the right drug at the right time. We here aim to summarize and discuss a possible workflow for precision medicine for cancer patients by reviewing recent booming technologies and treatments that have been used or will potentially be used in the CPM system.Entities:
Keywords: HLA; TCR-engineered T cells; immunopharmacogenomics; liquid biopsy; neoantigen and shared-antigen vaccine; personalized immunotherapy
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Year: 2016 PMID： 27842888 DOI： 10.1016/j.tips.2016.10.013
Source DB: PubMed Journal: Trends Pharmacol Sci ISSN： 0165-6147 Impact factor: 14.819