Literature DB >> 2784003

v-cbl, an oncogene from a dual-recombinant murine retrovirus that induces early B-lineage lymphomas.

W Y Langdon1, J W Hartley, S P Klinken, S K Ruscetti, H C Morse.   

Abstract

Cas NS-1 is an acutely transforming murine retrovirus that induces pre-B and pro-B cell lymphomas. Molecular cloning showed it was generated from the ecotropic Cas-Br-M virus by sequential recombinations with endogenous retroviral sequences and a cellular oncogene. The oncogene sequence shows no homology with known oncogenes but some similarity to the yeast transcriptional activator GCN4. A 100-kDa gag-cbl fusion protein, with no detectable kinase activity, is responsible for the cellular transformation. The cellular homologue of v-cbl, present in mouse and human DNA, is expressed in a range of hemopoietic lineages.

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Year:  1989        PMID： 2784003      PMCID： PMC286647          DOI： 10.1073/pnas.86.4.1168

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  45 in total

1.  Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.

Authors:  P S Thomas
Journal:  Proc Natl Acad Sci U S A       Date:  1980-09       Impact factor: 11.205

2.  Nucleotide sequence of Moloney murine leukaemia virus.

Authors:  T M Shinnick; R A Lerner; J G Sutcliffe
Journal:  Nature       Date:  1981 Oct 15-21       Impact factor: 49.962

3.  Cellular origin and role of mink cell focus-forming viruses in murine thymic lymphomas.

Authors:  S K Chattopadhyay; M W Cloyd; D L Linemeyer; M R Lander; E Rands; D R Lowy
Journal:  Nature       Date:  1982-01-07       Impact factor: 49.962

4.  Characterization of a protein found in cells infected with the spleen focus-forming virus that shares immunological cross-reactivity with the gp70 found in mink cell focus-inducing virus particles.

Authors:  S K Ruscetti; D Linemeyer; J Feild; D Troxler; E M Scolnick
Journal:  J Virol       Date:  1979-06       Impact factor: 5.103

5.  Heteroduplex analysis of the sequence relationships between the genomes of Kirsten and Harvey sarcoma viruses, their respective parental murine leukemia viruses, and the rat endogenous 30S RNA.

Authors:  U H Chien; M Lai; T Y Shih; I M Verma; E M Scolnick; P Roy-Burman; N Davidson
Journal:  J Virol       Date:  1979-09       Impact factor: 5.103

6.  Identification of ecotropic proviral sequences in inbred mouse strains with a cloned subgenomic DNA fragment.

Authors:  H W Chan; T Bryan; J L Moore; S P Staal; W P Rowe; M A Martin
Journal:  Proc Natl Acad Sci U S A       Date:  1980-10       Impact factor: 11.205

7.  A new class of murine leukemia virus associated with development of spontaneous lymphomas.

Authors:  J W Hartley; N K Wolford; L J Old; W P Rowe
Journal:  Proc Natl Acad Sci U S A       Date:  1977-02       Impact factor: 11.205

8.  Abelson murine leukaemia virus protein is phosphorylated in vitro to form phosphotyrosine.

Authors:  O N Witte; A Dasgupta; D Baltimore
Journal:  Nature       Date:  1980-02-28       Impact factor: 49.962

9.  DNA sequencing with chain-terminating inhibitors.

Authors:  F Sanger; S Nicklen; A R Coulson
Journal:  Proc Natl Acad Sci U S A       Date:  1977-12       Impact factor: 11.205

10.  Expression of the immunoglobulin C mu gene in mouse T and B lymphoid and myeloid cell lines.

Authors:  D J Kemp; A W Harris; S Cory; J M Adams
Journal:  Proc Natl Acad Sci U S A       Date:  1980-05       Impact factor: 11.205
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  76 in total

1.  The Cbl proto-oncogene product negatively regulates the Src-family tyrosine kinase Fyn by enhancing its degradation.

Authors:  C E Andoniou; N L Lill; C B Thien; M L Lupher; S Ota; D D Bowtell; R M Scaife; W Y Langdon; H Band
Journal:  Mol Cell Biol       Date:  2000-02       Impact factor: 4.272

2.  Cbl-transforming variants trigger a cascade of molecular alterations that lead to epithelial mesenchymal conversion.

Authors:  T M Fournier; L Lamorte; C R Maroun; M Lupher; H Band; W Langdon; M Park
Journal:  Mol Biol Cell       Date:  2000-10       Impact factor: 4.138

3.  Platelet alpha IIb-beta 3 integrin engagement induces the tyrosine phosphorylation of Cbl and its association with phosphoinositide 3-kinase and Syk.

Authors:  A Saci; F Rendu; C Bachelot-Loza
Journal:  Biochem J       Date:  2000-11-01       Impact factor: 3.857

Review 4.  Comparative map for mice and humans.

Authors:  J H Nadeau; M T Davisson; D P Doolittle; P Grant; A L Hillyard; M R Kosowsky; T H Roderick
Journal:  Mamm Genome       Date:  1992       Impact factor: 2.957

5.  Akap200 suppresses the effects of Dv-cbl expression in the Drosophila eye.

Authors:  Rowena T Sannang; Hannah Robertson; Nicole A Siddall; Gary R Hime
Journal:  Mol Cell Biochem       Date:  2012-07-08       Impact factor: 3.396

6.  Structural Determinants of the Gain-of-Function Phenotype of Human Leukemia-associated Mutant CBL Oncogene.

Authors:  Scott A Nadeau; Wei An; Bhopal C Mohapatra; Insha Mushtaq; Timothy A Bielecki; Haitao Luan; Neha Zutshi; Gulzar Ahmad; Matthew D Storck; Masashi Sanada; Seishi Ogawa; Vimla Band; Hamid Band
Journal:  J Biol Chem       Date:  2017-01-12       Impact factor: 5.157

7.  Oncogenic Signaling by Leukemia-Associated Mutant Cbl Proteins.

Authors:  Scott Nadeau; Wei An; Nick Palermo; Dan Feng; Gulzar Ahmad; Lin Dong; Gloria E O Borgstahl; Amarnath Natarajan; Mayumi Naramura; Vimla Band; Hamid Band
Journal:  Biochem Anal Biochem       Date:  2012-07-30

8.  Casitas B-cell lymphoma mutation in childhood T-cell acute lymphoblastic leukemia.

Authors:  Yuka Saito; Yoko Aoki; Hideki Muramatsu; Hideki Makishima; Jaroslaw P Maciejewski; Masue Imaizumi; Takeshi Rikiishi; Yoji Sasahara; Shigeo Kure; Tetsuya Niihori; Shigeru Tsuchiya; Seiji Kojima; Yoichi Matsubara
Journal:  Leuk Res       Date:  2012-05-14       Impact factor: 3.156

9.  Novel c-CBL and CBL-b ubiquitin ligase mutations in human acute myeloid leukemia.

Authors:  Michael A Caligiuri; Roger Briesewitz; Jianhua Yu; Lisheng Wang; Min Wei; Kristy J Arnoczky; Trent B Marburger; Jing Wen; Danilo Perrotti; Clara D Bloomfield; Susan P Whitman
Journal:  Blood       Date:  2007-05-02       Impact factor: 22.113

10.  Identification of a common viral integration region in Cas-Br-E murine leukemia virus-induced non-T-, non-B-cell lymphomas.

Authors:  D Bergeron; L Poliquin; C A Kozak; E Rassart
Journal:  J Virol       Date:  1991-01       Impact factor: 5.103
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