| Literature DB >> 27830569 |
Anoop K Patel1, Harman S Suri2, Jaskaran Singh1, Dinesh Kumar3, Shoaib Shafique4, Andrew Nicolaides5, Sanjay K Jain1, Luca Saba6, Ajay Gupta7, John R Laird8, Argiris Giannopoulos9, Jasjit S Suri10,11,12,13.
Abstract
Functional and structural changes in the common carotid artery are biomarkers for cardiovascular risk. Current methods for measuring functional changes include pulse wave velocity, compliance, distensibility, strain, stress, stiffness, and elasticity derived from arterial waveforms. The review is focused on the ultrasound-based carotid artery elasticity and stiffness measurements covering the physics of elasticity and linking it to biological evolution of arterial stiffness. The paper also presents evolution of plaque with a focus on the pathophysiologic cascade leading to arterial hardening. Using the concept of strain, and image-based elasticity, the paper then reviews the lumen diameter and carotid intima-media thickness measurements in combined temporal and spatial domains. Finally, the review presents the factors which influence the understanding of atherosclerotic disease formation and cardiovascular risk including arterial stiffness, tissue morphological characteristics, and image-based elasticity measurement.Entities:
Keywords: Atherosclerosis; Elasticity; Risk stratification; Stiffness; Tissue characterization; Ultrasound; Vascular
Mesh：
Year: 2016 PMID： 27830569 DOI： 10.1007/s11883-016-0635-9
Source DB: PubMed Journal: Curr Atheroscler Rep ISSN： 1523-3804 Impact factor: 5.113