BACKGROUND: Accurate, noninvasive, and inexpensive methods are required to measure infant body composition. Ultrasound (US) and bioimpedance spectroscopy (BIS) have been validated in adults and introduced in pediatric populations. The aim of this study was to evaluate the performance of both methods in determining percentage fat mass (%FM) in breastfed infants. METHODS: %FM of 2, 5, 9, and 12 mo-old healthy, breastfed term infants (n = 58) was calculated using BIS-derived total body water equations and skinfold equations then compared with reference models. Skinfolds were measured with US at two and four sites (biceps, suprailiac and/or triceps, and subscapular). RESULTS: %FM differed widely within and between methods, with the degree of variation affected by infant age/sex. Not a single method/equation was consistent with the distributions of appropriate reference values for all age/sex groups. Moderate number of matches with references values (13-24 out of 36) was seen for both types of equations. High number of matches (25-36) was seen for US skinfold-based equations. %FM values calculated from US and BIS were not significantly different (P = 0.35). CONCLUSION: Both BIS and US are practical for predicting %FM in infants. BIS calculations are highly dependent upon an appropriate set of validated age-matched equations.
BACKGROUND: Accurate, noninvasive, and inexpensive methods are required to measure infant body composition. Ultrasound (US) and bioimpedance spectroscopy (BIS) have been validated in adults and introduced in pediatric populations. The aim of this study was to evaluate the performance of both methods in determining percentage fat mass (%FM) in breastfed infants. METHODS: %FM of 2, 5, 9, and 12 mo-old healthy, breastfed term infants (n = 58) was calculated using BIS-derived total body water equations and skinfold equations then compared with reference models. Skinfolds were measured with US at two and four sites (biceps, suprailiac and/or triceps, and subscapular). RESULTS: %FM differed widely within and between methods, with the degree of variation affected by infant age/sex. Not a single method/equation was consistent with the distributions of appropriate reference values for all age/sex groups. Moderate number of matches with references values (13-24 out of 36) was seen for both types of equations. High number of matches (25-36) was seen for US skinfold-based equations. %FM values calculated from US and BIS were not significantly different (P = 0.35). CONCLUSION: Both BIS and US are practical for predicting %FM in infants. BIS calculations are highly dependent upon an appropriate set of validated age-matched equations.
Authors: Barbara E Lingwood; Anne-Martine Storm van Leeuwen; Angela E Carberry; Erin C Fitzgerald; Leonie K Callaway; Paul B Colditz; Leigh C Ward Journal: Br J Nutr Date: 2011-09-15 Impact factor: 3.718
Authors: Zoya Gridneva; Sambavi Kugananthan; Anna R Hepworth; Wan J Tie; Ching T Lai; Leigh C Ward; Peter E Hartmann; Donna T Geddes Journal: Nutrients Date: 2016-12-28 Impact factor: 5.717
Authors: Zoya Gridneva; Alethea Rea; Anna R Hepworth; Leigh C Ward; Ching T Lai; Peter E Hartmann; Donna T Geddes Journal: Nutrients Date: 2018-01-05 Impact factor: 5.717
Authors: Zoya Gridneva; Wan J Tie; Alethea Rea; Ching Tat Lai; Leigh C Ward; Kevin Murray; Peter E Hartmann; Donna T Geddes Journal: Nutrients Date: 2018-09-19 Impact factor: 5.717
Authors: Zoya Gridneva; Sambavi Kugananthan; Alethea Rea; Ching Tat Lai; Leigh C Ward; Kevin Murray; Peter E Hartmann; Donna T Geddes Journal: Nutrients Date: 2018-08-20 Impact factor: 5.717
Authors: Ali S Cheema; Lisa F Stinson; Alethea Rea; Ching Tat Lai; Matthew S Payne; Kevin Murray; Donna T Geddes; Zoya Gridneva Journal: Nutrients Date: 2021-10-22 Impact factor: 5.717
Authors: Zoya Gridneva; Ching T Lai; Alethea Rea; Wan J Tie; Leigh C Ward; Kevin Murray; Peter E Hartmann; Donna T Geddes Journal: Pediatr Res Date: 2020-05-21 Impact factor: 3.756
Authors: Ali S Cheema; Zoya Gridneva; Annalee J Furst; Ana S Roman; Michelle L Trevenen; Berwin A Turlach; Ching T Lai; Lisa F Stinson; Lars Bode; Matthew S Payne; Donna T Geddes Journal: Int J Mol Sci Date: 2022-03-05 Impact factor: 5.923