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Literature DB >> 27827481

Biological applications of xeno nucleic acids.

Kunihiko Morihiro¹, Yuuya Kasahara¹, Satoshi Obika¹.

Abstract

Xeno nucleic acids (XNAs) are a group of chemically modified nucleic acid analogues that have been applied to various biological technologies such as antisense oligonucleotides, siRNAs and aptamers.

Entities: Chemical

Mesh：

Substances：

Year: 2017 PMID： 27827481 DOI： 10.1039/c6mb00538a

Source DB: PubMed Journal: Mol Biosyst ISSN： 1742-2051

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Cited

17 in total

1. Double-headed nucleotides as xeno nucleic acids: information storage and polymerase recognition.

Authors: Kasper M Beck; Marie B Krogh; Mick Hornum; Paul T Ludford; Yitzhak Tor; Poul Nielsen
Journal: Org Biomol Chem Date: 2020-09-23 Impact factor: 3.876

Review 2. Small, but powerful and attractive: ¹⁹F in biomolecular NMR.

Authors: Angela M Gronenborn
Journal: Structure Date: 2021-12-13 Impact factor: 5.006

3. Viscoelastic and Thermoreversible Networks Crosslinked by Non-covalent Interactions Between "Clickable" Nucleic Acids Oligomers and DNA.

Authors: Alex J Anderson; Heidi R Culver; Stephanie J Bryant; Christopher N Bowman
Journal: Polym Chem Date: 2020-03-20 Impact factor: 5.582

Review 4. Perspectives on conformationally constrained peptide nucleic acid (PNA): insights into the structural design, properties and applications.

Authors: Chaturong Suparpprom; Tirayut Vilaivan
Journal: RSC Chem Biol Date: 2022-03-18

5. A modular XNAzyme cleaves long, structured RNAs under physiological conditions and enables allele-specific gene silencing.

Authors: Alexander I Taylor; Christopher J K Wan; Maria J Donde; Sew-Yeu Peak-Chew; Philipp Holliger
Journal: Nat Chem Date: 2022-09-05 Impact factor: 24.274

6. Inhibition of microRNA-33b specifically ameliorates abdominal aortic aneurysm formation via suppression of inflammatory pathways.

Authors: Tomohiro Yamasaki; Takahiro Horie; Satoshi Koyama; Tetsushi Nakao; Osamu Baba; Masahiro Kimura; Naoya Sowa; Kazuhisa Sakamoto; Kazuhiro Yamazaki; Satoshi Obika; Yuuya Kasahara; Jun Kotera; Kozo Oka; Ryo Fujita; Takashi Sasaki; Akihiro Takemiya; Koji Hasegawa; Kenji Minatoya; Takeshi Kimura; Koh Ono
Journal: Sci Rep Date: 2022-07-14 Impact factor: 4.996

Biological applications of xeno nucleic acids.

1. Double-headed nucleotides as xeno nucleic acids: information storage and polymerase recognition.

Review 2. Small, but powerful and attractive: ¹⁹F in biomolecular NMR.

3. Viscoelastic and Thermoreversible Networks Crosslinked by Non-covalent Interactions Between "Clickable" Nucleic Acids Oligomers and DNA.

Review 4. Perspectives on conformationally constrained peptide nucleic acid (PNA): insights into the structural design, properties and applications.

5. A modular XNAzyme cleaves long, structured RNAs under physiological conditions and enables allele-specific gene silencing.

6. Inhibition of microRNA-33b specifically ameliorates abdominal aortic aneurysm formation via suppression of inflammatory pathways.

Review 7. Uptake mechanisms of cell-internalizing nucleic acid aptamers for applications as pharmacological agents.

8. The proto-Nucleic Acid Builder: a software tool for constructing nucleic acid analogs.

9. Energy Landscapes of Deoxyxylo- and Xylo-Nucleic Acid Octamers.

10. Synthesis and Evaluation of Artificial Nucleic Acid Bearing an Oxanorbornane Scaffold.

Review 2. Small, but powerful and attractive: 19F in biomolecular NMR.

Review 4. Perspectives on conformationally constrained peptide nucleic acid (PNA): insights into the structural design, properties and applications.

Review 7. Uptake mechanisms of cell-internalizing nucleic acid aptamers for applications as pharmacological agents.

Review 2. Small, but powerful and attractive: ¹⁹F in biomolecular NMR.