Literature DB >> 27826877

Antimicrobial Stewardship and Environmental Decontamination for the Control of Clostridium difficile Transmission in Healthcare Settings.

Jason Bintz1, Suzanne Lenhart2, Cristina Lanzas3.   

Abstract

We implement an agent-based model for Clostridium difficile transmission in hospitals that accounts for several processes and individual factors including environmental and antibiotic heterogeneity in order to evaluate the efficacy of various control measures aimed at reducing environmental contamination and mitigating the effects of antibiotic use on transmission. In particular, we account for local contamination levels that contribute to the probability of colonization and we account for both the number and type of antibiotic treatments given to patients. Simulations illustrate the relative efficacy of several strategies for the reduction of nosocomial colonizations and nosocomial diseases.

Entities:  

Keywords:  Agent-based model; Clostridium difficile; Control

Mesh：

Substances：

Year:  2016        PMID： 27826877      PMCID： PMC5495002          DOI： 10.1007/s11538-016-0224-7

Source DB:  PubMed          Journal:  Bull Math Biol        ISSN： 0092-8240            Impact factor:   1.758


  32 in total

1.  Critical role of nosocomial transmission in the toronto sars outbreak.

Authors:  Glenn F Webb; Martin J Blaser; Huaiping Zhu; Sten Ardal; Jianhong Wu
Journal:  Math Biosci Eng       Date:  2004-06       Impact factor: 2.080

2.  Modeling antibiotic resistance in hospitals: the impact of minimizing treatment duration.

Authors:  Erika M C D'Agata; Pierre Magal; Damien Olivier; Shigui Ruan; Glenn F Webb
Journal:  J Theor Biol       Date:  2007-08-25       Impact factor: 2.691

Review 3.  Diagnosis of Clostridium difficile infection by toxin detection kits: a systematic review.

Authors:  Tim Planche; Adamma Aghaizu; Richard Holliman; Peter Riley; Jan Poloniecki; Aodhán Breathnach; Sanjeev Krishna
Journal:  Lancet Infect Dis       Date:  2008-11-01       Impact factor: 25.071

Review 4.  Clostridium difficile infection.

Authors:  Daniel A Leffler; J Thomas Lamont
Journal:  N Engl J Med       Date:  2015-04-16       Impact factor: 91.245

5.  Some simple nosocomial disease transmission models.

Authors:  Fred Brauer
Journal:  Bull Math Biol       Date:  2015-01-22       Impact factor: 1.758

6.  Impact of visitors and hospital staff on nosocomial transmission and spread to community.

Authors:  Ying-Hen Hsieh; Junli Liu; Yun-Huei Tzeng; Jianhong Wu
Journal:  J Theor Biol       Date:  2014-04-13       Impact factor: 2.691

Review 7.  Antibiotics and hospital-acquired Clostridium difficile infection: update of systematic review and meta-analysis.

Authors:  Claudia Slimings; Thomas V Riley
Journal:  J Antimicrob Chemother       Date:  2013-12-08       Impact factor: 5.790

8.  Risk factors for Clostridium difficile infection.

Authors:  G E Bignardi
Journal:  J Hosp Infect       Date:  1998-09       Impact factor: 3.926

Review 9.  Update on the changing epidemiology of Clostridium difficile-associated disease.

Authors:  Lynne V McFarland
Journal:  Nat Clin Pract Gastroenterol Hepatol       Date:  2008-01

Review 10.  Clostridium difficile infection: new developments in epidemiology and pathogenesis.

Authors:  Maja Rupnik; Mark H Wilcox; Dale N Gerding
Journal:  Nat Rev Microbiol       Date:  2009-07       Impact factor: 60.633
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  5 in total

1.  Modeling Infectious Diseases in Healthcare Network (MInD-Healthcare) Framework for Describing and Reporting Multidrug-resistant Organism and Healthcare-Associated Infections Agent-based Modeling Methods.

Authors:  Rachel B Slayton; Justin J O'Hagan; Sean Barnes; Sarah Rhea; Rainer Hilscher; Michael Rubin; Eric Lofgren; Brajendra Singh; Alberto Segre; Prabasaj Paul
Journal:  Clin Infect Dis       Date:  2020-12-03       Impact factor: 9.079

2.  EnABLe: An agent-based model to understand Listeria dynamics in food processing facilities.

Authors:  Claire Zoellner; Rachel Jennings; Martin Wiedmann; Renata Ivanek
Journal:  Sci Rep       Date:  2019-01-24       Impact factor: 4.379

3.  Metapopulation Model from Pathogen's Perspective: A Versatile Framework to Quantify Pathogen Transfer and Circulation between Environment and Hosts.

Authors:  Shi Chen; Cristina Lanzas; Chihoon Lee; Gabriel L Zenarosa; Ahmed A Arif; Michael Dulin
Journal:  Sci Rep       Date:  2019-02-08       Impact factor: 4.379

4.  Modeling inpatient and outpatient antibiotic stewardship interventions to reduce the burden of Clostridioides difficile infection in a regional healthcare network.

Authors:  Sarah Rhea; Kasey Jones; Stacy Endres-Dighe; Breda Munoz; David J Weber; Rainer Hilscher; Jennifer MacFarquhar; Emily Sickbert-Bennett; Lauren DiBiase; Ashley Marx; James Rineer; James Lewis; Georgiy Bobashev
Journal:  PLoS One       Date:  2020-06-11       Impact factor: 3.240

5.  Mathematically modeling the effect of touch frequency on the environmental transmission of Clostridioides difficile in healthcare settings.

Authors:  Cara Jill Sulyok; Lindsey Fox; Hannah Ritchie; Cristina Lanzas; Suzanne Lenhart; Judy Day
Journal:  Math Biosci       Date:  2021-07-24       Impact factor: 3.935
  5 in total

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