| Literature DB >> 27822759 |
A I Autenshlyus1,2, T A Kunts3, K V Karpukhina2, E S Mikhaylova1,2, N A Varaksin4, I O Marinkin1, V V Lyakhovich2.
Abstract
Cytokine production was evaluated in supernatants of cultured tumor cells that were obtained by biopsy of the breast invasive ductal carcinoma (IDC) and breast fibroadenoma (FA) and grown in vitro. In the IDC supernatants, the concentrations of pro-inflammatory (pro-oncogenic) cytokines IL-17, IL-18, and IFNγ and of IL-1 receptor antagonist were significantly higher than in the FA cell supernatants. The concentrations of anti-inflammatory cytokine IL-10 and MCP-1 protein in supernatants of IDC cells were significantly lower than those determined in FA supernatants.Entities:
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Year: 2016 PMID： 27822759 DOI： 10.1134/S0012496616050057
Source DB: PubMed Journal: Dokl Biol Sci ISSN： 0012-4966