Literature DB >> 27822758

Effect of polypeptides from sea anemone Heteractis crispa on the rodent blood pressure, heart rate, and hemostasis.

L A Skobtsova1,2, I A Dyachenko3,4, Ya A Andreev5, Yu A Logashina5, A N Murashev1,2, E V Grishin5.   

Abstract

АРНС1-3 peptides, modulators of TRPV1 receptors, have been administered to SD rats to study their influence on the animal hemostatic system, heart rate, and blood pressure. None of АЗРС1-3 polypeptides have any effect on the hemostatic system. Both АРНС1 and АРНС2 polypeptides increased significantly the heart rate, but they did not affect blood pressure, which was probably caused by an ability of these polypeptides to modify animal thermoregulation.

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Year:  2016        PMID： 27822758     DOI： 10.1134/S0012496616050069

Source DB:  PubMed          Journal:  Dokl Biol Sci        ISSN： 0012-4966


  5 in total

1.  Biological activity of a polypeptide modulator of TRPV1 receptor.

Authors:  I A Dyachenko; Ya A Andreev; Yu A Logashina; A N Murashev; E V Grishin
Journal:  Dokl Biol Sci       Date:  2016-01-05

2.  Analgesic effect of a polypeptide inhibitor of the TRPV1 receptor in noxious heat pain models.

Authors:  Y A Andreev; S A Kozlov; E P Kozlovskaya; E V Grishin
Journal:  Dokl Biochem Biophys       Date:  2009 Jan-Feb       Impact factor: 0.788

3.  Cyanogen bromide cleavage of proteins in salt and buffer solutions.

Authors:  Yaroslav A Andreev; Sergey A Kozlov; Alexander A Vassilevski; Eugene V Grishin
Journal:  Anal Biochem       Date:  2010-07-27       Impact factor: 3.365

4.  Modulation of TRPV1-dependent contractility of normal and diabetic bladder smooth muscle by analgesic toxins from sea anemone Heteractis crispa.

Authors:  Igor B Philyppov; Oksana N Paduraru; Yaroslav A Andreev; Eugene V Grishin; Yaroslav M Shuba
Journal:  Life Sci       Date:  2012-09-12       Impact factor: 5.037

5.  Polypeptide modulators of TRPV1 produce analgesia without hyperthermia.

Authors:  Yaroslav A Andreev; Sergey A Kozlov; Yuliya V Korolkova; Igor A Dyachenko; Dmitrii A Bondarenko; Denis I Skobtsov; Arkadii N Murashev; Polina D Kotova; Olga A Rogachevskaja; Natalia V Kabanova; Stanislav S Kolesnikov; Eugene V Grishin
Journal:  Mar Drugs       Date:  2013-12-16       Impact factor: 5.118
  5 in total

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