Literature DB >> 27817181

Reprogramming Enhancers in Somatic Cell Nuclear Transfer, iPSC Technology, and Direct Conversion.

Daekee Kwon1, Minjun Ji1, Seunghee Lee1, Kwang Won Seo2,3, Kyung-Sun Kang4,5.   

Abstract

Direct conversion of cell fate is a core technology for future regenerative medicine. However, the low reprogramming efficiency and low reproducibility are the largest obstacles blocking translational research of direct conversion technology. This review lists the major reprogramming enhancers verified in the representative reprogramming technologies of somatic cell nuclear transfer, induced pluripotent stem cell technology, and direct conversion, and categorizes them according to their functions. Ultimately, we strive to provide a practical plan to overcome the low reprogramming efficiency and low reproducibility of direct conversion.

Keywords:  Direct conversion; Induced pluripotent stem cells; Reprogramming; Reprogramming efficiency; Reprogramming enhancer; Somatic cell nuclear transfer

Mesh：

Year:  2017        PMID： 27817181     DOI： 10.1007/s12015-016-9697-x

Source DB:  PubMed          Journal:  Stem Cell Rev Rep        ISSN： 2629-3277            Impact factor:   5.739


  88 in total

1.  The developmental capacity of nuclei taken from differentiating endoderm cells of Xenopus laevis.

Authors:  J B GURDON
Journal:  J Embryol Exp Morphol       Date:  1960-12

2.  Neural stem cells directly differentiated from partially reprogrammed fibroblasts rapidly acquire gliogenic competency.

Authors:  Takeshi Matsui; Morito Takano; Kenji Yoshida; Soichiro Ono; Chikako Fujisaki; Yumi Matsuzaki; Yoshiaki Toyama; Masaya Nakamura; Hideyuki Okano; Wado Akamatsu
Journal:  Stem Cells       Date:  2012-06       Impact factor: 6.277

3.  Hypoxia enhances the generation of induced pluripotent stem cells.

Authors:  Yoshinori Yoshida; Kazutoshi Takahashi; Keisuke Okita; Tomoko Ichisaka; Shinya Yamanaka
Journal:  Cell Stem Cell       Date:  2009-08-27       Impact factor: 24.633

4.  Viable offspring derived from fetal and adult mammalian cells.

Authors:  I Wilmut; A E Schnieke; J McWhir; A J Kind; K H Campbell
Journal:  Nature       Date:  1997-02-27       Impact factor: 49.962

5.  Suppression of induced pluripotent stem cell generation by the p53-p21 pathway.

Authors:  Hyenjong Hong; Kazutoshi Takahashi; Tomoko Ichisaka; Takashi Aoi; Osami Kanagawa; Masato Nakagawa; Keisuke Okita; Shinya Yamanaka
Journal:  Nature       Date:  2009-08-09       Impact factor: 49.962

6.  Variation in the safety of induced pluripotent stem cell lines.

Authors:  Kyoko Miura; Yohei Okada; Takashi Aoi; Aki Okada; Kazutoshi Takahashi; Keisuke Okita; Masato Nakagawa; Michiyo Koyanagi; Koji Tanabe; Mari Ohnuki; Daisuke Ogawa; Eiji Ikeda; Hideyuki Okano; Shinya Yamanaka
Journal:  Nat Biotechnol       Date:  2009-07-09       Impact factor: 54.908

7.  Inhibition of PTEN tumor suppressor promotes the generation of induced pluripotent stem cells.

Authors:  Jiyuan Liao; Tomotoshi Marumoto; Saori Yamaguchi; Shinji Okano; Naoki Takeda; Chika Sakamoto; Hirotaka Kawano; Takenobu Nii; Shohei Miyamato; Yoko Nagai; Michiyo Okada; Hiroyuki Inoue; Kohichi Kawahara; Akira Suzuki; Yoshie Miura; Kenzaburo Tani
Journal:  Mol Ther       Date:  2013-04-09       Impact factor: 11.454

8.  Histone Demethylase Expression Enhances Human Somatic Cell Nuclear Transfer Efficiency and Promotes Derivation of Pluripotent Stem Cells.

Authors:  Young Gie Chung; Shogo Matoba; Yuting Liu; Jin Hee Eum; Falong Lu; Wei Jiang; Jeoung Eun Lee; Vicken Sepilian; Kwang Yul Cha; Dong Ryul Lee; Yi Zhang
Journal:  Cell Stem Cell       Date:  2015-10-29       Impact factor: 24.633

9.  Direct cell reprogramming is a stochastic process amenable to acceleration.

Authors:  Jacob Hanna; Krishanu Saha; Bernardo Pando; Jeroen van Zon; Christopher J Lengner; Menno P Creyghton; Alexander van Oudenaarden; Rudolf Jaenisch
Journal:  Nature       Date:  2009-11-08       Impact factor: 49.962

10.  In vivo reprogramming of adult pancreatic exocrine cells to beta-cells.

Authors:  Qiao Zhou; Juliana Brown; Andrew Kanarek; Jayaraj Rajagopal; Douglas A Melton
Journal:  Nature       Date:  2008-08-27       Impact factor: 49.962
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  7 in total

1.  Looking Back at the Past Year of Stem Cell Reviews and Reports.

Authors:  Mariusz Z Ratajczak
Journal:  Stem Cell Rev Rep       Date:  2017-12       Impact factor: 5.739

2.  Epigenetic Enzymes, Age, and Ancestry Regulate the Efficiency of Human iPSC Reprogramming.

Authors:  Lantz C Mackey; Lois A Annab; Jun Yang; Bhargavi Rao; Grace E Kissling; Shepard H Schurman; Darlene Dixon; Trevor K Archer
Journal:  Stem Cells       Date:  2018-10-17       Impact factor: 6.277

3.  Dnmt1s in donor cells is a barrier to SCNT-mediated DNA methylation reprogramming in pigs.

Authors:  Xuexiong Song; Zhonghua Liu; Hongbin He; Jianyu Wang; Huatao Li; Jingyu Li; Fangzheng Li; Zhongling Jiang; Yanjun Huan
Journal:  Oncotarget       Date:  2017-05-23

Review 4.  The essentiality of non-coding RNAs in cell reprogramming.

Authors:  Joachim Luginbühl; Divya Mundackal Sivaraman; Jay W Shin
Journal:  Noncoding RNA Res       Date:  2017-04-13

5.  Generation of Genetically Stable Human Direct-Conversion-Derived Neural Stem Cells Using Quantity Control of Proto-oncogene Expression.

Authors:  Kwon Daekee; Han Mi-Jung; Ji Minjun; Ahn Hee-Jin; Seo Kwang-Won; Kang Kyung-Sun
Journal:  Mol Ther Nucleic Acids       Date:  2018-12-20       Impact factor: 8.886

Review 6.  Motor neuron-derived induced pluripotent stem cells as a drug screening platform for amyotrophic lateral sclerosis.

Authors:  Mariana A Amorós; Esther S Choi; Axel R Cofré; Nikolay V Dokholyan; Marcelo Duzzioni
Journal:  Front Cell Dev Biol       Date:  2022-08-24

7.  Determination of Oocyte-Manipulation, Zygote-Manipulation, and Genome-Reprogramming Effects on the Transcriptomes of Bovine Blastocysts.

Authors:  Byungkuk Min; Jung S Park; Yong-Kook Kang
Journal:  Front Genet       Date:  2018-04-24       Impact factor: 4.599
  7 in total

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