Literature DB >> 2781279

Molecular structure of DNA by scanning tunneling microscopy.

A Cricenti1, S Selci, A C Felici, R Generosi, E Gori, W Djaczenko, G Chiarotti.   

Abstract

Uncoated DNA molecules marked with an activated tris(l-aziridinyl) phosphine oxide (TAPO) solution were deposited on gold substrates and imaged in air with the use of a high-resolution scanning tunneling microscope (STM). Constant-current and gap-modulated STM images show clear evidence of the helicity of the DNA structure: pitch periodicity ranges from 25 to 35 angstroms, whereas the average diameter is 20 angstroms. Molecular structure within a single helix turn was also observed.

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Year:  1989        PMID： 2781279     DOI： 10.1126/science.2781279

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  5 in total

1.  Immobilization of DNA for scanning probe microscopy.

Authors:  D P Allison; L A Bottomley; T Thundat; G M Brown; R P Woychik; J J Schrick; K B Jacobson; R J Warmack
Journal:  Proc Natl Acad Sci U S A       Date:  1992-11-01       Impact factor: 11.205

2.  Potentiostatic deposition of DNA for scanning probe microscopy.

Authors:  S M Lindsay; N J Tao; J A DeRose; P I Oden; R E Harrington; L Shlyakhtenko
Journal:  Biophys J       Date:  1992-06       Impact factor: 4.033

3.  Atomic force microscopy of long DNA: imaging in air and under water.

Authors:  Y Lyubchenko; L Shlyakhtenko; R Harrington; P Oden; S Lindsay
Journal:  Proc Natl Acad Sci U S A       Date:  1993-03-15       Impact factor: 11.205

4.  Masking generates contiguous segments of metal-coated and bare DNA for scanning tunneling microscope imaging.

Authors:  D D Dunlap; R García; E Schabtach; C Bustamante
Journal:  Proc Natl Acad Sci U S A       Date:  1993-08-15       Impact factor: 11.205

5.  Scanning tunneling microscopy imaging of Torpedo acetylcholine receptor.

Authors:  A Bertazzon; B M Conti-Tronconi; M A Raftery
Journal:  Proc Natl Acad Sci U S A       Date:  1992-10-15       Impact factor: 11.205
  5 in total

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