Literature DB >> 27811930

Defining the brain circuits involved in psychiatric disorders: IMI-NEWMEDS.

Francesc Artigas1,2,3, Esther Schenker4, Pau Celada1,2,3, Michael Spedding4, Laia Lladó-Pelfort1,2,3, Noemi Jurado1,2,3, Mercedes Núñez1,2,3, Noemi Santana1,2,3, Eva Troyano-Rodriguez1,2,3, Maurizio S Riga1,2,3, Hanna van den Munkhof1,2,3, Anna Castañé1,2,3, Hamdy Shaban5, Thérèse M Jay6, Anushree Tripathi6, Bill P Godsil6, Claude Sebban7, Jean Mariani7, Philippe Faure7, Samir Takkilah7, Zoe A Hughes8, Chester J Siok8, Mihaily Hajos8, Karsten Wicke9, Natalia Gass10, Wolfgang Weber-Fahr10, Alexander Sartorius10, Robert Becker10, Michael Didriksen11, Jesper F Bastlund11, Mark Tricklebank12, Céline Risterucci13, Andreas Meyer-Lindenberg10, Adam J Schwarz14.   

Abstract

Despite the vast amount of research on schizophrenia and depression in the past two decades, there have been few innovative drugs to treat these disorders. Precompetitive research collaborations between companies and academic groups can help tackle this innovation deficit, as illustrated by the achievements of the IMI-NEWMEDS consortium.

Entities:  

Mesh:

Substances:

Year:  2016        PMID: 27811930     DOI: 10.1038/nrd.2016.205

Source DB:  PubMed          Journal:  Nat Rev Drug Discov        ISSN: 1474-1776            Impact factor:   84.694


  5 in total

1.  Acute ketamine challenge increases resting state prefrontal-hippocampal connectivity in both humans and rats.

Authors:  Oliver Grimm; Natalia Gass; Wolfgang Weber-Fahr; Alexander Sartorius; Esther Schenker; Michael Spedding; Celine Risterucci; Janina Isabel Schweiger; Andreas Böhringer; Zhenxiang Zang; Heike Tost; Adam James Schwarz; Andreas Meyer-Lindenberg
Journal:  Psychopharmacology (Berl)       Date:  2015-07-18       Impact factor: 4.530

2.  Phencyclidine-induced disruption of oscillatory activity in prefrontal cortex: Effects of antipsychotic drugs and receptor ligands.

Authors:  L Lladó-Pelfort; E Troyano-Rodriguez; H E van den Munkhof; A Cervera-Ferri; N Jurado; M Núñez-Calvet; F Artigas; P Celada
Journal:  Eur Neuropsychopharmacol       Date:  2015-11-19       Impact factor: 4.600

3.  Activation of thalamocortical networks by the N-methyl-D-aspartate receptor antagonist phencyclidine: reversal by clozapine.

Authors:  Noemí Santana; Eva Troyano-Rodriguez; Guadalupe Mengod; Pau Celada; Francesc Artigas
Journal:  Biol Psychiatry       Date:  2011-01-20       Impact factor: 13.382

Review 4.  The hippocampal-prefrontal pathway: the weak link in psychiatric disorders?

Authors:  Bill P Godsil; Janos P Kiss; Michael Spedding; Thérèse M Jay
Journal:  Eur Neuropsychopharmacol       Date:  2013-01-15       Impact factor: 4.600

5.  Phencyclidine inhibits the activity of thalamic reticular gamma-aminobutyric acidergic neurons in rat brain.

Authors:  Eva Troyano-Rodriguez; Laia Lladó-Pelfort; Noemi Santana; Vicent Teruel-Martí; Pau Celada; Francesc Artigas
Journal:  Biol Psychiatry       Date:  2014-06-05       Impact factor: 13.382

  5 in total
  8 in total

1.  NMDA receptor antagonists traxoprodil and lanicemine improve hippocampal-prefrontal coupling and reward-related networks in rats.

Authors:  Robert Becker; Natalia Gass; Lothar Kußmaul; Bernhard Schmid; Stefan Scheuerer; David Schnell; Cornelia Dorner-Ciossek; Wolfgang Weber-Fahr; Alexander Sartorius
Journal:  Psychopharmacology (Berl)       Date:  2019-07-02       Impact factor: 4.530

2.  Abnormal neural activation patterns underlying working memory impairment in chronic phencyclidine-treated mice.

Authors:  Yosefu Arime; Kazufumi Akiyama
Journal:  PLoS One       Date:  2017-12-18       Impact factor: 3.240

Review 3.  New drugs in psychiatry: focus on new pharmacological targets.

Authors:  Filippo Caraci; Gian Marco Leggio; Salvatore Salomone; Filippo Drago
Journal:  F1000Res       Date:  2017-03-30

4.  Systemic neurotransmitter responses to clinically approved and experimental neuropsychiatric drugs.

Authors:  Hamid R Noori; Lewis H Mervin; Vahid Bokharaie; Özlem Durmus; Lisamon Egenrieder; Stefan Fritze; Britta Gruhlke; Giulia Reinhardt; Hans-Hendrik Schabel; Sabine Staudenmaier; Nikos K Logothetis; Andreas Bender; Rainer Spanagel
Journal:  Nat Commun       Date:  2018-11-08       Impact factor: 14.919

5.  Serotonin Neuronal Function from the Bed to the Bench: Is This Really a Mirrored Way?

Authors:  Adeline Etievant; Thorsten Lau; Guillaume Lucas; Nasser Haddjeri
Journal:  eNeuro       Date:  2019-06-05

6.  Phenotypical Screening on Neuronal Plasticity in Hippocampal-Prefrontal Cortex Connectivity Reveals an Antipsychotic with a Novel Profile.

Authors:  Michael Spedding; Claude Sebban; Thérèse M Jay; Cyril Rocher; Brigitte Tesolin-Decros; Paul Chazot; Esther Schenker; Gabor Szénási; György I Lévay; Katalin Megyeri; Jozsef Barkóczy; Laszlo G Hársing; Ian Thomson; Mark O Cunningham; Miles A Whittington; Lori-An Etherington; Jeremy J Lambert; Ferenc A Antoni; Istvan Gacsályi
Journal:  Cells       Date:  2022-03-31       Impact factor: 6.600

7.  Lateral habenula perturbation reduces default-mode network connectivity in a rat model of depression.

Authors:  Christian Clemm von Hohenberg; Wolfgang Weber-Fahr; Philipp Lebhardt; Namasivayam Ravi; Urs Braun; Natalia Gass; Robert Becker; Markus Sack; Alejandro Cosa Linan; Martin Fungisai Gerchen; Jonathan Rochus Reinwald; Lars-Lennart Oettl; Andreas Meyer-Lindenberg; Barbara Vollmayr; Wolfgang Kelsch; Alexander Sartorius
Journal:  Transl Psychiatry       Date:  2018-03-27       Impact factor: 6.222

8.  Cognition- and circuit-based dysfunction in a mouse model of 22q11.2 microdeletion syndrome: effects of stress.

Authors:  Anushree Tripathi; Michael Spedding; Esther Schenker; Michael Didriksen; Arnaud Cressant; Therese M Jay
Journal:  Transl Psychiatry       Date:  2020-01-28       Impact factor: 6.222

  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.