Literature DB >> 27809693

Clinical outcome and health-related quality-of-life following microsurgical reconstruction in patients with oral and oropharyngeal cancer.

Shems Al-Hayder1, Jens Jørgen Elberg2, Birgitte Charabi3.   

Abstract

CONCLUSION: Radial forearm free flap (RFFF) and fibula free flap (FFF) provide high safety and reliability with low incidence of free flap failure and an acceptable level of complications and health-related quality-of-life (HRQoL).
OBJECTIVES: To determine the clinical outcomes and long-term HRQoL in patients with oral or oropharyngeal cancer following free flap reconstruction.
METHODS: A retrospective review of medical records and self-administered HRQoL questionnaires, EORTC QLQ-C30, and -H&N35. All patients who underwent surgery for oral or oropharyngeal cancer followed by primary reconstruction by RFFF or FFF at Rigshospitalet between September 2001 and November 2011 were included.
RESULTS: The study comprised 19 patients still alive out of 61 patients. The free flap success rate was 94.7%. Early post-operative complications occurred in 11 patients (57.9%); however, only three cases (15.8%) required re-surgery. Nine patients (47.4%) developed late complications, including mandibular osteoradionecrosis in six cases (31.6%). Most patients obtained acceptable values of global quality-of-life and relatively high scores on the functional scales.

Entities:  

Keywords:  Head and neck neoplasms; free tissue flaps; post-operative complications; quality-of-life

Mesh:

Year:  2016        PMID: 27809693     DOI: 10.1080/00016489.2016.1249945

Source DB:  PubMed          Journal:  Acta Otolaryngol        ISSN: 0001-6489            Impact factor:   1.494


  4 in total

1.  Quality of life in patients after reconstruction with the supraclavicular artery island flap (SCAIF) versus the radial free forearm flap (RFFF).

Authors:  Jennifer L Spiegel; Yiannis Pilavakis; Bernhard G Weiss; Martin Canis; Christian Welz
Journal:  Eur Arch Otorhinolaryngol       Date:  2019-05-27       Impact factor: 2.503

2.  Quality of life after free flap surgery for cancer of the head and neck in patients with or without postoperative complications.

Authors:  Sanna Lahtinen; Petri Koivunen; Tero Ala-Kokko; Päivi Laurila; Outi Kaarela; Janne H Liisanantti
Journal:  Eur Arch Otorhinolaryngol       Date:  2018-08-24       Impact factor: 2.503

3.  Long-term functional and esthetic outcomes after fibula free flap reconstruction of the mandible.

Authors:  Ivana Petrovic; Raymond Baser; Timothy Blackwell; Colleen McCarthy; Ian Ganly; Snehal Patel; Peter Cordeiro; Jatin Shah
Journal:  Head Neck       Date:  2019-02-13       Impact factor: 3.147

4.  [Functional outcome after transmandibular resection and primary chemoradiation in advanced oropharyngeal squamous cell carcinoma].

Authors:  A Knopf; N Mansour; B Hofauer; F Johnson; H Bier; F Wakonig; S Teutsch
Journal:  HNO       Date:  2021-02       Impact factor: 1.284

  4 in total

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