Literature DB >> 27804868

Gallium-68 in Medical Imaging.

Lucia Martiniova, Louis De Palatis, Elba Etchebehere, Gregory Ravizzini1.   

Abstract

Over the past several years, Positron Emission Tomography (PET) imaging agents labeled with ;68Gallium (68Ga) have undergone a significant increase in clinical utilization. 68Ga is conveniently produced from a germanium-68/gallium-68 (68Ge/68Ga) generator. Because of the compact size and ease of use of the generator, 68Ga labeled compounds may be more cost-effective than PET radioisotopes that are cyclotron-produced. The convenient half-life of 68Ga (T1/2=68 min) provides sufficient radioactivity for various PET imaging applications, while delivering acceptable radiation doses to patients. This chapter summarizes the emerging clinical utilization of 68Ga-based radiotracers in medical imaging. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

Entities:  

Keywords:  68Gallium; PSMA.; generator; neuroendocrine tumors; positron emission tomography; somatostatin receptor scintigraphy

Mesh:

Substances:

Year:  2016        PMID: 27804868     DOI: 10.2174/1874471009666161028150654

Source DB:  PubMed          Journal:  Curr Radiopharm        ISSN: 1874-4710


  10 in total

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2.  Cyclotron-based production of 68Ga, [68Ga]GaCl3, and [68Ga]Ga-PSMA-11 from a liquid target.

Authors:  Melissa E Rodnick; Carina Sollert; Daniela Stark; Mara Clark; Andrew Katsifis; Brian G Hockley; D Christian Parr; Jens Frigell; Bradford D Henderson; Monica Abghari-Gerst; Morand R Piert; Michael J Fulham; Stefan Eberl; Katherine Gagnon; Peter J H Scott
Journal:  EJNMMI Radiopharm Chem       Date:  2020-11-12

Review 3.  Prostate-Specific Membrane Antigen as Target for Neuroimaging of Central Nervous System Tumors.

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Journal:  Mol Imaging       Date:  2022-04-15       Impact factor: 3.250

Review 4.  The Role of [68Ga]Ga-DOTA-SSTR PET Radiotracers in Brain Tumors: A Systematic Review of the Literature and Ongoing Clinical Trials.

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Review 5.  Positron Emission Tomography Radiopharmaceuticals in Differentiated Thyroid Cancer.

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6.  Studies towards elucidating the potential of 5,10,15,20-tetrakis(p-carboxy-methyleneoxyphenyl)porphyrin as a theranostic agent for applications in PET and PDT.

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Review 7.  Diagnostics and Therapeutics in Targeting HER2 Breast Cancer: A Novel Approach.

Authors:  Chris Vi; Giovanni Mandarano; Sarah Shigdar
Journal:  Int J Mol Sci       Date:  2021-06-07       Impact factor: 5.923

Review 8.  Theragnostic Aspects and Radioimmunotherapy in Pediatric Tumors.

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Journal:  Int J Mol Sci       Date:  2020-05-28       Impact factor: 5.923

9.  Peptide-Based 68Ga-PET Radiotracer for Imaging PD-L1 Expression in Cancer.

Authors:  Ravindra A De Silva; Dhiraj Kumar; Ala Lisok; Samit Chatterjee; Bryan Wharram; Kalagadda Venkateswara Rao; Ronnie Mease; Robert F Dannals; Martin G Pomper; Sridhar Nimmagadda
Journal:  Mol Pharm       Date:  2018-08-10       Impact factor: 4.939

10.  Benefit of Later-Time-Point PET Imaging of HER3 Expression Using Optimized Radiocobalt-Labeled Affibody Molecules.

Authors:  Sara S Rinne; Charles Dahlsson Leitao; Zahra Saleh-Nihad; Bogdan Mitran; Vladimir Tolmachev; Stefan Ståhl; John Löfblom; Anna Orlova
Journal:  Int J Mol Sci       Date:  2020-03-13       Impact factor: 5.923

  10 in total

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