| Literature DB >> 27798655 |
Samir El Alaoui1, Nils Lindefors1.
Abstract
BACKGROUND: A major challenge of mental health care is to provide safe and effective treatment with limited resources. The main purpose of this study was to examine a value-based approach in clinical psychiatry when evaluating a process improvement initiative. This was accomplished by using the relatively new time driven activity based costing (TDABC) method within the more widely adopted cost-effectiveness analysis framework for economic evaluation of healthcare technologies. The objective was to evaluate the cost-effectiveness of allowing psychologists to perform post-treatment assessment previously performed by psychiatrists at an outpatient clinic treating depression using internet-based cognitive-behavioral therapy (ICBT).Entities:
Mesh:
Year: 2016 PMID: 27798655 PMCID: PMC5087942 DOI: 10.1371/journal.pone.0165389
Source DB: PubMed Journal: PLoS One ISSN: 1932-6203 Impact factor: 3.240
Patient characteristics.
| Year | N | Mean | Std. Deviation | Std. Error Mean | |
|---|---|---|---|---|---|
| 2013 | 279 | 37,35 | 12,32 | 0,74 | |
| 2014 | 385 | 37,42 | 12,08 | 0,62 | |
| 2013 | 279 | 30% | 0,46 | 0,03 | |
| 2014 | 385 | 32% | 0,47 | 0,02 | |
| 2013 | 280 | 192,54 | 111,69 | 6,67 | |
| 2014 | 386 | 173,43 | 126,39 | 6,43 | |
| 2013 | 281 | 7,27 | 3,06 | 0,18 | |
| 2014 | 386 | 7,28 | 3,03 | 0,15 | |
| 2013 | 278 | 14,69 | 4,97 | 0,30 | |
| 2014 | 378 | 14,11 | 4,88 | 0,25 | |
| 2013 | 243 | 8,65 | 5,54 | 0,36 | |
| 2014 | 325 | 8,45 | 5,70 | 0,32 | |
| 2013 | 123 | 6,93 | 5,88 | 0,53 | |
| 2014 | 135 | 6,90 | 6,03 | 0,52 | |
| 2013 | 240 | 25,05 | 4,52 | 0,29 | |
| 2014 | 322 | 25,43 | 4,58 | 0,26 |
Calculation of statistics.
| Post-treatment (n = 568) | Follow-up (n = 258) | |||||
|---|---|---|---|---|---|---|
| Intervention group (2014) | Control group (2013) | Difference | Intervention group (2014) | Control group (2013) | Difference | |
| 325 | 243 | 135 | 123 | |||
| Mean ( | 27.4% (44.7%) | 27.2% (44.6%) | 0.2% | 42.2% (49.6%) | 42.3% (49.6%) | -0.1% |
| Standard error of mean | 0.025 | 0.029 | 0.038 | 0.043 | 0.045 | 0.062 |
| Mean ( | 646 (161) | 680 (135) | -35 | 659 (134) | 709 (130) | -49 |
| Standard error of mean | 9 | 9 | 12 | 12 | 12 | 16 |
| Covariance | -0.191 | 3.242 | 0.013 | -5.060 | -4.028 | -0.070 |
| Correlation | -0.003 | 0.041 | 0.027 | -0.076 | -0.062 | -0.069 |
| -$15,398 | $91,113 | |||||
Note. SD, standard deviation; ICER, Incremental cost-effectiveness ratio.
Capacity cost rates for internet-based cognitive therapy in the treatment of depression.
| Coordinating nurse | Medical secretary | Psychologist | Resident physician | Medical specialist | |
|---|---|---|---|---|---|
| $1.25 | $1.05 | $1.28 | $1.44 | $2.20 |
Fig 1Incremental cost-effectiveness plane showing the mean differences in costs and in the primary outcome measure at post-treatment with 50%, 75% or 95% confidence-ellipses around the point estimate.
Fig 2Incremental cost-effectiveness plane showing the mean differences in costs and in the primary outcome measure at follow-up with 50%, 75% or 95% confidence-ellipses around the point estimate.
Fig 3Cost-effectiveness acceptability curves at after treatment and at follow-up based on the willingness to pay for an additional remission from depression achieved, considering the total costs of healthcare.
Fig 4Net monetary benefit curves and 95% confidence intervals at post-treatment and at follow-up.
Incremental net benefit.
| Post-treatment | Follow-up | |||||||
|---|---|---|---|---|---|---|---|---|
| WTP | E(INB) | 95% CI for INB | Q | E(INB) | 95% CI for INB | Q | ||
| $0 | $35 | $10 | $59 | 0.997 | $49 | $17 | $82 | 0.999 |
| $5 000 | $46 | -$325 | $417 | 0.595 | $47 | -$562 | $656 | 0.560 |
| $10 000 | $57 | -$684 | $798 | 0.560 | $44 | -$1 170 | $1 258 | 0.528 |
| $15 000 | $68 | -$1 044 | $1 180 | 0.548 | $41 | -$1 779 | $1 861 | 0.518 |
| $20 000 | $79 | -$1 403 | $1 562 | 0.542 | $39 | -$2 387 | $2 464 | 0.512 |
| $25 000 | $91 | -$1 763 | $1 944 | 0.538 | $36 | -$2 995 | $3 067 | 0.509 |
| $30 000 | $102 | -$2 122 | $2 326 | 0.536 | $33 | -$3 604 | $3 670 | 0.507 |
| $35 000 | $113 | -$2 482 | $2 708 | 0.534 | $30 | -$4 212 | $4 273 | 0.506 |
| $40 000 | $124 | -$2 841 | $3 090 | 0.533 | $28 | -$4 821 | $4 876 | 0.504 |
| $45 000 | $135 | -$3 201 | $3 472 | 0.532 | $25 | -$5 429 | $5 479 | 0.504 |
| $50 000 | $147 | -$3 560 | $3 854 | 0.531 | $22 | -$6 038 | $6 082 | 0.503 |
Note. WTP, willingness-to-pay; Q, probability of being cost-effective.