Literature DB >> 27793804

Osteochondral Allograft Donor-Host Matching by the Femoral Condyle Radius of Curvature.

Derek T Bernstein1, Craig A O'Neill1, Ryan S Kim2, Hugh L Jones2, Philip C Noble2, Joshua D Harris1, Patrick C McCulloch1.   

Abstract

BACKGROUND: Conventional osteochondral allograft (OCA) matching, requiring orthotopic, size-matched condyles, and narrow surgical time windows often prohibit timely transplantation. HYPOTHESIS: The femoral condyle radius of curvature (RoC) is an appropriate, isolated criterion for donor-host matching in fresh OCAs, potentially enhancing matching efficiency when compared with conventional matching techniques. STUDY
DESIGN: Descriptive laboratory study.
METHODS: In part 1 of this study, 3-dimensional digital reconstructions of 14 randomly selected, cadaveric distal femoral hemicondyles were performed. Each condyle was divided into anterior, middle, and posterior zones. A virtual best-fit grid was applied to each, and each zone's sagittal- and coronal-plane RoCs were determined. Seven nonorthotopic OCA transplantations were performed based on RoC matching with 1-mm tolerance, and the preoperative and postoperative surface geometry were quantified to assess the accuracy of articular surface restoration. Of note, each donor-host pair did not match by the conventional method. In part 2 of this study, 12 cadaveric distal femora were categorized by size and digitized in the aforementioned manner. Simulated circular defects measuring 20, 25, and 30 mm in diameter were introduced into each zone. OCA matches were determined based on donor and host RoCs, and the total number of potential matches (of 71 total comparisons) was recorded as a percentage for each simulated defect. Finally, the results of RoC matching were compared with the conventional method for simulated defects in all zones of both the medial and lateral femoral condyles.
RESULTS: Part 1: The mean surface deviation after OCA transplantation was -0.09 mm, with a mean maximum protrusion at any point of 0.59 mm. Part 2: Using the RoC, 20-mm defects had a 100% chance of being matched. Defects of 25 and 30 mm had a 91% and 64% chance of being matched, respectively. Compared with the conventional method, the RoC method yielded a 3.2-fold greater match rate for lesions of the medial and lateral femoral condyles ( P = .02).
CONCLUSION: This investigation shows that femoral condyle RoCs in the sagittal and coronal planes may be useful, alternative matching criteria, expanding on current standards. CLINICAL RELEVANCE: These matching criteria may increase the number of available matches, reduce wait times for patients, and reduce the number of wasted grafts.

Entities:  

Keywords:  chondral defects; femoral condyle radius of curvature; osteochondral allograft

Mesh:

Year:  2016        PMID: 27793804     DOI: 10.1177/0363546516671519

Source DB:  PubMed          Journal:  Am J Sports Med        ISSN: 0363-5465            Impact factor:   6.202


  9 in total

1.  Topographic Analysis of the Distal Femoral Condyle Articular Cartilage Surface: Adequacy of the Graft from Opposite Condyles of the Same or Different Size for the Osteochondral Allograft Transplantation.

Authors:  Adam B Yanke; Atsushi Urita; Jason J Shin; Greg L Cvetanovich; Erin K Moran; Bernard R Bach; Brian J Cole; Nozomu Inoue; Nikhil N Verma
Journal:  Cartilage       Date:  2018-01-16       Impact factor: 4.634

2.  A Radiographic Sizing Algorithm for Tibial Plateau Osteochondral Allografts.

Authors:  David P Trofa; William C Graham; Kirk A McCullough; Christian Lattermann; David C Flanigan; Keith T Corpus; Bryan M Saltzman; James E Fleischli; Dana P Piasecki
Journal:  Cartilage       Date:  2019-03-12       Impact factor: 4.634

3.  Long-Term Retrospective Follow-Up of Fresh Osteochondral Allograft Transplantation for Steroid-Associated Osteonecrosis of the Femoral Condyles.

Authors:  Samuel Early; Luís E P Tírico; Pamela A Pulido; Julie C McCauley; William D Bugbee
Journal:  Cartilage       Date:  2018-10-31       Impact factor: 4.634

4.  Ideal Donor Site for Osteochondral Autografting of the Distal Femur Using Radius of Curvature: A 3-Dimensional High-Resolution Scanner Comparison.

Authors:  Patrick A Massey; Michael T Lowery; Garrett Houk; Kaylan N McClary; R Shane Barton; Giovanni F Solitro
Journal:  Cartilage       Date:  2021-04-15       Impact factor: 3.117

5.  Fresh Osteochondral Allograft Transplantation for Focal Chondral Defect of the Humerus Associated With Anchor Arthropathy and Failed SLAP Repair.

Authors:  Kevin C Wang; Brian R Waterman; Eric J Cotter; Rachel M Frank; Brian J Cole
Journal:  Arthrosc Tech       Date:  2017-08-28

6.  An Expert Consensus Statement on the Management of Large Chondral and Osteochondral Defects in the Patellofemoral Joint.

Authors:  Jorge Chahla; Betina B Hinckel; Adam B Yanke; Jack Farr; William D Bugbee; James L Carey; Brian J Cole; Dennis C Crawford; James E Fleischli; Alan Getgood; Andreas H Gomoll; Simon Gortz; Allan E Gross; Deryk G Jones; Aaron J Krych; Christian Lattermann; Bert R Mandelbaum; Peter R Mandt; Tom Minas; Raffy Mirzayan; Timothy S Mologne; John D Polousky; Matthew T Provencher; Scott A Rodeo; Oleg Safir; Seth Lawrence Sherman; Eric D Strauss; Sabrina M Strickland; Christopher J Wahl; Riley J Williams
Journal:  Orthop J Sports Med       Date:  2020-03-26

7.  Contralateral Lateral Femoral Condyle Allografts Provide an Acceptable Surface Match for Simulated Classic Osteochondritis Dissecans Lesions of the Medial Femoral Condyle.

Authors:  Nabeel Salka; John A Grant
Journal:  Orthop J Sports Med       Date:  2020-01-28

Review 8.  Osteochondral Allografts in Knee Surgery: Narrative Review of Evidence to Date.

Authors:  Wilson C Lai; Hunter L Bohlen; Nathan P Fackler; Dean Wang
Journal:  Orthop Res Rev       Date:  2022-08-11

9.  Metrics of OsteoChondral Allografts (MOCA) Group Consensus Statements on the Use of Viable Osteochondral Allograft.

Authors:  Simon Görtz; Suzanne M Tabbaa; Deryk G Jones; John D Polousky; Dennis C Crawford; William D Bugbee; Brian J Cole; Jack Farr; James E Fleischli; Alan Getgood; Andreas H Gomoll; Allan E Gross; Aaron J Krych; Christian Lattermann; Bert R Mandelbaum; Peter R Mandt; Raffy Mirzayan; Timothy S Mologne; Matthew T Provencher; Scott A Rodeo; Oleg Safir; Eric D Strauss; Christopher J Wahl; Riley J Williams; Adam B Yanke
Journal:  Orthop J Sports Med       Date:  2021-03-23
  9 in total

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