Literature DB >> 27790553

Efficacy of Platelet Rich Plasma via Lumbar Epidural Route in Chronic Prolapsed Intervertebral Disc Patients-A Pilot Study.

Rohan Bhatia1, Gaurav Chopra2.   

Abstract

INTRODUCTION: Lumbar radiculopathy is a major health problem often treated by surgery or guided lumbar epidural steroids for pain relief. We have used Platelet Rich Plasma (PRP) a novel therapeutic tool of autologous nature that has emerged strongly in recent years to treat patients of prolapsed intervertebral disc. AIM: To evaluate the efficacy of PRP via interlaminar epidural route in treatment of pain in patients with prolapsed inter vertebral disc.
MATERIALS AND METHODS: Ten patients were injected with five ml of autologous platelet rich plasma under fluoroscopic guidance via interlaminar lumbar epidural injection into area of affected nerve root. They were followed using VAS (Visual Analogue Scale), SLRT (Straight Leg Raising Test) and MODQ (Modified Oswestry Disability Questionnaire) for clinical improvement.
RESULTS: Patients who had received epidural injections of autologous PRP showed improvements in their scores of evaluation tools. Improvement was sustained during the 3 month study period and was not associated with any complications.
CONCLUSION: Autologous PRP can be considered as a good alternative to epidural steroids and surgery in management of patients with chronic prolapsed intervertebral disc.

Entities:  

Keywords:  Autologous platelet rich plasma; Fluoroscopy; Interlaminar

Year:  2016        PMID: 27790553      PMCID: PMC5072053          DOI: 10.7860/JCDR/2016/21863.8482

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  5 in total

Review 1.  Musculoskeletal applications of platelet-rich plasma: fad or future?

Authors:  Kenneth S Lee; John J Wilson; David P Rabago; Geoffrey S Baer; Jon A Jacobson; Camilo G Borrero
Journal:  AJR Am J Roentgenol       Date:  2011-03       Impact factor: 3.959

Review 2.  Platelet rich plasma. A new treatment tool for the rheumatologist?

Authors:  José De La Mata
Journal:  Reumatol Clin       Date:  2012-08-16

3.  Human platelet-rich plasma promotes axon growth in brain-spinal cord coculture.

Authors:  Michiko Takeuchi; Naosuke Kamei; Rikuo Shinomiya; Toru Sunagawa; Osami Suzuki; Hiroto Kamoda; Seiji Ohtori; Mitsuo Ochi
Journal:  Neuroreport       Date:  2012-08-22       Impact factor: 1.837

Review 4.  Epidural steroids: a comprehensive, evidence-based review.

Authors:  Steven P Cohen; Mark C Bicket; David Jamison; Indy Wilkinson; James P Rathmell
Journal:  Reg Anesth Pain Med       Date:  2013 May-Jun       Impact factor: 6.288

5.  Sensory improvement of leprosy peripheral neuropathy in patients treated with perineural injection of platelet-rich plasma.

Authors:  Sukma Anjayani; Yohanes Widodo Wirohadidjojo; Andi Muhammad Adam; Danny Suwandi; Arifin Seweng; Muh Dali Amiruddin
Journal:  Int J Dermatol       Date:  2013-10-29       Impact factor: 2.736

  5 in total
  7 in total

Review 1.  Platelet-rich plasma injections: an emerging therapy for chronic discogenic low back pain.

Authors:  Suja Mohammed; James Yu
Journal:  J Spine Surg       Date:  2018-03

2.  PAST, CURRENT AND FUTURE INTERVENTIONAL ORTHOBIOLOGICS TECHNIQUES AND HOW THEY RELATE TO REGENERATIVE REHABILITATION: A CLINICAL COMMENTARY.

Authors:  Christopher J Centeno; Sarah M Pastoriza
Journal:  Int J Sports Phys Ther       Date:  2020-04

3.  The use of lumbar epidural injection of platelet lysate for treatment of radicular pain.

Authors:  Christopher Centeno; Jason Markle; Ehren Dodson; Ian Stemper; Matthew Hyzy; Christopher Williams; Michael Freeman
Journal:  J Exp Orthop       Date:  2017-11-25

Review 4.  Systemic Review: Is an Intradiscal Injection of Platelet-Rich Plasma for Lumbar Disc Degeneration Effective?

Authors:  Takashi Hirase; Robert A Jack Ii; Kyle R Sochacki; Joshua D Harris; Bradley K Weiner
Journal:  Cureus       Date:  2020-06-25

Review 5.  Effect of Platelet-Rich Plasma on Intervertebral Disc Degeneration In Vivo and In Vitro: A Critical Review.

Authors:  Yvang Chang; Ming Yang; Song Ke; Yu Zhang; Gang Xu; Zhonghai Li
Journal:  Oxid Med Cell Longev       Date:  2020-11-21       Impact factor: 6.543

6.  Transforaminal Endoscopic Lumbar Discectomy with versus without Platelet-Rich Plasma Injection for Lumbar Disc Herniation: A Prospective Cohort Study.

Authors:  Yi Jiang; Rujun Zuo; Shuai Yuan; Jian Li; Chang Liu; Jiexun Zhang; Ming Ma; Dasheng Li; Yong Hai
Journal:  Pain Res Manag       Date:  2022-03-07       Impact factor: 3.037

7.  Ultrasound-Guided Transforaminal Injections of Platelet-Rich Plasma Compared with Steroid in Lumbar Disc Herniation: A Prospective, Randomized, Controlled Study.

Authors:  Zhen Xu; Shaoling Wu; Xiao Li; Cuicui Liu; Shengnuo Fan; Chao Ma
Journal:  Neural Plast       Date:  2021-05-27       Impact factor: 3.599

  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.