| Literature DB >> 27789843 |
Marc de Manuel1, Martin Kuhlwilm1, Peter Frandsen2, Vitor C Sousa3, Tariq Desai4, Javier Prado-Martinez5, Jessica Hernandez-Rodriguez1, Isabelle Dupanloup3, Oscar Lao6, Pille Hallast7, Joshua M Schmidt8, José María Heredia-Genestar1, Andrea Benazzo9, Guido Barbujani9, Benjamin M Peter10, Lukas F K Kuderna1, Ferran Casals1, Samuel Angedakin11, Mimi Arandjelovic11, Christophe Boesch11, Hjalmar Kühl11, Linda Vigilant11, Kevin Langergraber12, John Novembre10, Marta Gut13, Ivo Gut13, Arcadi Navarro14, Frands Carlsen15, Aida M Andrés8, Hans R Siegismund16, Aylwyn Scally4, Laurent Excoffier3, Chris Tyler-Smith17, Sergi Castellano8, Yali Xue17, Christina Hvilsom18, Tomas Marques-Bonet19.
Abstract
Our closest living relatives, chimpanzees and bonobos, have a complex demographic history. We analyzed the high-coverage whole genomes of 75 wild-born chimpanzees and bonobos from 10 countries in Africa. We found that chimpanzee population substructure makes genetic information a good predictor of geographic origin at country and regional scales. Multiple lines of evidence suggest that gene flow occurred from bonobos into the ancestors of central and eastern chimpanzees between 200,000 and 550,000 years ago, probably with subsequent spread into Nigeria-Cameroon chimpanzees. Together with another, possibly more recent contact (after 200,000 years ago), bonobos contributed less than 1% to the central chimpanzee genomes. Admixture thus appears to have been widespread during hominid evolution.Entities:
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Year: 2016 PMID： 27789843 PMCID： PMC5546212 DOI： 10.1126/science.aag2602
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728