Emily Reeve1,2, Lee-Fay Low3, Sepehr Shakib4,5, Sarah N Hilmer6,7. 1. Cognitive Decline Partnership Centre, Kolling Institute of Medical Research, Northern Clinical School, University of Sydney, Sydney, NSW, Australia. emily.reeve@sydney.edu.au. 2. Geriatric Medicine Research, Faculty of Medicine, Queen Elizabeth II Health Sciences Centre, Dalhousie University and Nova Scotia Health Authority, Rm. 1315 Camp Hill Veterans' Memorial Building, 5955 Veterans' Memorial Lane, Halifax, NS, B3H 2E1, Canada. emily.reeve@sydney.edu.au. 3. Faculty of Health Sciences, University of Sydney, Sydney, NSW, Australia. 4. Department of Clinical Pharmacology, Royal Adelaide Hospital, Adelaide, SA, Australia. 5. Department of Clinical Pharmacology, Faculty of Health Science, School of Medicine, University of Adelaide, Adelaide, SA, Australia. 6. Cognitive Decline Partnership Centre, Kolling Institute of Medical Research, Northern Clinical School, University of Sydney, Sydney, NSW, Australia. 7. Departments of Aged Care and Clinical Pharmacology, Royal North Shore Hospital, St Leonards, NSW, Australia.
Abstract
BACKGROUND: Knowledge of consumer (patient and caregiver) attitudes is essential for conducting medication optimization in practice. OBJECTIVES: The aim of this study was to develop and validate a questionnaire to capture older adults' and caregivers' beliefs and attitudes towards deprescribing. METHODS: The previously validated Patients' Attitudes Towards Deprescribing (PATD) questionnaire was expanded based on literature review, expert opinion and focus groups, and a caregivers' version was developed. The revised questionnaire was piloted and then distributed for self-completion to older adults (≥65 years of age), taking at least one regular medication and caregivers of older adults. Psychometric validity and reliability were examined. Responses to questions that were identified to group into a specific factor were combined to produce a score. RESULTS: A total of 383 consumer questionnaires and 200 caregiver questionnaires were completed and included in analysis. Exploratory factor analysis revealed four factors in both versions of the questionnaire (with four to five questions retained in each factor). The factors relate to the perceived burden of medication taking, belief in appropriateness of medication use (harms and benefits), concerns about stopping the medication, and level of involvement/knowledge of medications. Internal consistency of all factors was acceptable with Cronbach's alpha >0.6. In both the older adults' and caregivers' versions, the burden score was inversely associated with the appropriateness score (p < 0.001 both versions). Factor scores between administration times (test-retest reliability) were statistically significantly correlated (p = 0.000), with gamma values ranging between 0.57 and 0.89. CONCLUSION: The revised PATD questionnaire had acceptable validity and reliability. This newly validated questionnaire may provide insight into individuals' willingness for/barriers to deprescribing, with applications in practice and research.
BACKGROUND: Knowledge of consumer (patient and caregiver) attitudes is essential for conducting medication optimization in practice. OBJECTIVES: The aim of this study was to develop and validate a questionnaire to capture older adults' and caregivers' beliefs and attitudes towards deprescribing. METHODS: The previously validated Patients' Attitudes Towards Deprescribing (PATD) questionnaire was expanded based on literature review, expert opinion and focus groups, and a caregivers' version was developed. The revised questionnaire was piloted and then distributed for self-completion to older adults (≥65 years of age), taking at least one regular medication and caregivers of older adults. Psychometric validity and reliability were examined. Responses to questions that were identified to group into a specific factor were combined to produce a score. RESULTS: A total of 383 consumer questionnaires and 200 caregiver questionnaires were completed and included in analysis. Exploratory factor analysis revealed four factors in both versions of the questionnaire (with four to five questions retained in each factor). The factors relate to the perceived burden of medication taking, belief in appropriateness of medication use (harms and benefits), concerns about stopping the medication, and level of involvement/knowledge of medications. Internal consistency of all factors was acceptable with Cronbach's alpha >0.6. In both the older adults' and caregivers' versions, the burden score was inversely associated with the appropriateness score (p < 0.001 both versions). Factor scores between administration times (test-retest reliability) were statistically significantly correlated (p = 0.000), with gamma values ranging between 0.57 and 0.89. CONCLUSION: The revised PATD questionnaire had acceptable validity and reliability. This newly validated questionnaire may provide insight into individuals' willingness for/barriers to deprescribing, with applications in practice and research.
Authors: Emily Reeve; Michael D Wiese; Ivanka Hendrix; Michael S Roberts; Sepehr Shakib Journal: J Am Geriatr Soc Date: 2013-08-26 Impact factor: 5.562
Authors: Simon J Griffin; Ann-Louise Kinmonth; Marijcke W M Veltman; Susan Gillard; Julie Grant; Moira Stewart Journal: Ann Fam Med Date: 2004 Nov-Dec Impact factor: 5.166
Authors: Mark E Williams; Charles C Pulliam; Rebecca Hunter; Ted M Johnson; Justine E Owens; Jean Kincaid; Carol Porter; Gary Koch Journal: J Am Geriatr Soc Date: 2004-01 Impact factor: 5.562
Authors: Dedan Opondo; Saied Eslami; Stefan Visscher; Sophia E de Rooij; Robert Verheij; Joke C Korevaar; Ameen Abu-Hanna Journal: PLoS One Date: 2012-08-22 Impact factor: 3.240
Authors: Jennifer Tjia; Jean S Kutner; Christine S Ritchie; Patrick J Blatchford; Rachael E Bennett Kendrick; Maryjo Prince-Paul; Tamara J Somers; Mary Lynn McPherson; Jeff A Sloan; Amy P Abernethy; Jon P Furuno Journal: J Palliat Med Date: 2017-05-18 Impact factor: 2.947
Authors: Emily Reeve; Jennifer L Wolff; Maureen Skehan; Elizabeth A Bayliss; Sarah N Hilmer; Cynthia M Boyd Journal: JAMA Intern Med Date: 2018-12-01 Impact factor: 21.873
Authors: Yee Lin Chock; Yuan Lin Wee; Su Lene Gan; Kah Woon Teoh; Khuen Yen Ng; Shaun Wen Huey Lee Journal: J Gen Intern Med Date: 2021-06-25 Impact factor: 5.128