Literature DB >> 27785607

Plastic strains during stent deployment have a critical influence on the rate of corrosion in absorbable magnesium stents.

Emmet Galvin1, Christy Cummins2, Shoichiro Yoshihara3, Bryan J Mac Donald4, Caitríona Lally5.   

Abstract

Magnesium stents are a promising candidate in the emerging field of absorbable metallic stents (AMSs). In this study, the mechanical and corrosion performance of dog-bone specimens and a specific stent design of a magnesium alloy, WE43, are assessed experimentally in terms of their corrosion behaviour and mechanical integrity. It is shown that plastic strains that are induced in the struts of the stent during stent deployment have a critical influence in directing subsequent corrosion behaviour within the material. In addition, the deployment and scaffolding characteristics of the magnesium stent are elucidated and contrasted with those of a commercial stainless steel stent. The magnesium stent is found to support higher levels of cyclic strain amplitude than the stainless steel stent, even prior to degradation, and this may play a role in reducing in-stent restenosis. This study provides new insights into the experimental performance of a current AMS design and material whilst demonstrating the critical influence of plastic strain on the corrosion performance and scaffolding ability of an AMS.

Entities:  

Keywords:  Absorbable metallic stents; Biodegradable magnesium alloys; Biomaterials; Cyclic strain; WE43

Mesh:

Substances:

Year:  2016        PMID: 27785607     DOI: 10.1007/s11517-016-1584-8

Source DB:  PubMed          Journal:  Med Biol Eng Comput        ISSN: 0140-0118            Impact factor:   2.602


  20 in total

1.  Quantification of vessel wall cyclic strain using cine phase contrast magnetic resonance imaging.

Authors:  Mary T Draney; Robert J Herfkens; Thomas J R Hughes; Norbert J Pelc; Kristin L Wedding; Christopher K Zarins; Charles A Taylor
Journal:  Ann Biomed Eng       Date:  2002-09       Impact factor: 3.934

2.  Bioresorbable scaffold: the advent of a new era in percutaneous coronary and peripheral revascularization?

Authors:  Yosinobu Onuma; Patrick W Serruys
Journal:  Circulation       Date:  2011-02-22       Impact factor: 29.690

3.  A simplified in vivo approach for evaluating the bioabsorbable behavior of candidate stent materials.

Authors:  Daniel Pierson; Jacob Edick; Aaron Tauscher; Ellen Pokorney; Patrick Bowen; Jesse Gelbaugh; Jon Stinson; Heather Getty; Chee Huei Lee; Jaroslaw Drelich; Jeremy Goldman
Journal:  J Biomed Mater Res B Appl Biomater       Date:  2011-09-08       Impact factor: 3.368

4.  Experimental data confirm numerical modeling of the degradation process of magnesium alloys stents.

Authors:  Wei Wu; Shanshan Chen; Dario Gastaldi; Lorenza Petrini; Diego Mantovani; Ke Yang; Lili Tan; Francesco Migliavacca
Journal:  Acta Biomater       Date:  2012-11-02       Impact factor: 8.947

5.  The processing of ultrafine-grained Mg tubes for biodegradable stents.

Authors:  Qiang Ge; David Dellasega; Ali Gökhan Demir; Maurizio Vedani
Journal:  Acta Biomater       Date:  2013-01-17       Impact factor: 8.947

6.  Corrosion fatigue behaviors of two biomedical Mg alloys - AZ91D and WE43 - In simulated body fluid.

Authors:  X N Gu; W R Zhou; Y F Zheng; Y Cheng; S C Wei; S P Zhong; T F Xi; L J Chen
Journal:  Acta Biomater       Date:  2010-07-23       Impact factor: 8.947

Review 7.  The history of biodegradable magnesium implants: a review.

Authors:  Frank Witte
Journal:  Acta Biomater       Date:  2010-02-19       Impact factor: 8.947

8.  Influence of surface modification on the in vitro corrosion rate of magnesium alloy AZ31.

Authors:  Joy E Gray-Munro; Christine Seguin; Michael Strong
Journal:  J Biomed Mater Res A       Date:  2009-10       Impact factor: 4.396

9.  Safety and performance of the drug-eluting absorbable metal scaffold (DREAMS) in patients with de-novo coronary lesions: 12 month results of the prospective, multicentre, first-in-man BIOSOLVE-I trial.

Authors:  Michael Haude; Raimund Erbel; Paul Erne; Stefan Verheye; Hubertus Degen; Dirk Böse; Paul Vermeersch; Inge Wijnbergen; Neil Weissman; Francesco Prati; Ron Waksman; Jacques Koolen
Journal:  Lancet       Date:  2013-03-09       Impact factor: 79.321

10.  Temporary scaffolding of coronary arteries with bioabsorbable magnesium stents: a prospective, non-randomised multicentre trial.

Authors:  Raimund Erbel; Carlo Di Mario; Jozef Bartunek; Johann Bonnier; Bernard de Bruyne; Franz R Eberli; Paul Erne; Michael Haude; Bernd Heublein; Mark Horrigan; Charles Ilsley; Dirk Böse; Jacques Koolen; Thomas F Lüscher; Neil Weissman; Ron Waksman
Journal:  Lancet       Date:  2007-06-02       Impact factor: 79.321

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  1 in total

1.  In vivo and in vitro evaluation of a biodegradable magnesium vascular stent designed by shape optimization strategy.

Authors:  Chenxin Chen; Jiahui Chen; Wei Wu; Yongjuan Shi; Liang Jin; Lorenza Petrini; Li Shen; Guangyin Yuan; Wenjiang Ding; Junbo Ge; Elazer R Edelman; Francesco Migliavacca
Journal:  Biomaterials       Date:  2019-08-05       Impact factor: 12.479

  1 in total

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