| Literature DB >> 27782375 |
Dario L Longo1, Rachele Stefania2, Chiara Callari2, Francesco De Rose2, Riccardo Rolle2, Laura Conti2, Lorena Consolino2, Francesca Arena2, Silvio Aime2.
Abstract
A dynamic contrast enhanced (DCE) approach for tumor photoacoustic (PA) imaging is described. Novel water soluble melanin-based derivatives are synthesized that exhibit good PA properties, stability, safety and accumulation in tumor bearing mice. This melanin derivative is capable to characterize tumor vasculature and to monitor vessel permeability changes upon antiangiogenic treatment. DCE-PA imaging can assess functional response to cancer treatments.Entities:
Keywords: dynamic contrast enhanced; melanin; nanoparticles; photoacoustic; tumors
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Year: 2016 PMID: 27782375 DOI: 10.1002/adhm.201600550
Source DB: PubMed Journal: Adv Healthc Mater ISSN: 2192-2640 Impact factor: 9.933