Literature DB >> 27782272

C8-H bond activation vs. C2-H bond activation: from naphthyl amines to lactams.

Renyi Shi1, Lijun Lu1, Hangyu Xie1, Jingwen Yan1, Ting Xu2, Hua Zhang1, Xiaotian Qi2, Yu Lan2, Aiwen Lei3.   

Abstract

Pd-catalyzed selective amine-oriented C8-H bond functionalization/N-dealkylative carbonylation of naphthyl amines has been achieved. The amine group from dealkylation is proposed to be the directing group for promoting this process. It represents a straightforward and easy method to access various biologically important benzo[cd]indol-2(1H)-one derivatives.

Entities:  

Year:  2016        PMID： 27782272     DOI： 10.1039/c6cc06358f

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  4 in total

1.  Iridium-Catalyzed, Silyl-Directed, peri-Borylation of C-H Bonds in Fused Polycyclic Arenes and Heteroarenes.

Authors:  Bo Su; John F Hartwig
Journal:  Angew Chem Int Ed Engl       Date:  2018-07-13       Impact factor: 15.336

2.  Tertiary amine-directed and involved carbonylative cyclizations through Pd/Cu-cocatalyzed multiple C-X (X = H or N) bond cleavage.

Authors:  Qiu-Chao Mu; Yi-Xue Nie; Xing-Feng Bai; Jing Chen; Lei Yang; Zheng Xu; Li Li; Chun-Gu Xia; Li-Wen Xu
Journal:  Chem Sci       Date:  2019-08-19       Impact factor: 9.825

3.  Overcoming peri- and ortho-selectivity in C-H methylation of 1-naphthaldehydes by a tunable transient ligand strategy.

Authors:  Yujian Mao; Jing Jiang; Dandan Yuan; Xiuzhen Chen; Yanan Wang; Lihong Hu; Yinan Zhang
Journal:  Chem Sci       Date:  2022-01-06       Impact factor: 9.825

4.  Ruthenium-Catalyzed Peri- and Ortho-Alkynylation with Bromoalkynes via Insertion and Elimination.

Authors:  Eric Tan; Andrey I Konovalov; Gabriela A Fernández; Ruth Dorel; Antonio M Echavarren
Journal:  Org Lett       Date:  2017-10-04       Impact factor: 6.005
  4 in total

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