Literature DB >> 27780832

Outcome of babies with no detectable heart rate before 10 minutes of age, and the effect of gestation.

Thomas Sproat1, Richard Hearn1, Sundeep Harigopal1.   

Abstract

OBJECTIVE: Current resuscitation guidelines suggest that it is reasonable to consider stopping resuscitation where no heart rate (cardiac activity) has been detected for 10 min in a newborn baby from birth. We aimed to determine the mortality rate and 2-year neurodevelopmental outcome of all babies born with no heart rate before 10 min of age where resuscitation was attempted in a tertiary referral centre over a 5-year period.
DESIGN: To identify all babies with no heart rate before age 10 min we examined two groups:▸ All babies classified as live born who received cardiac massage at birth between January 2009 and December 2013.▸ All babies classified as stillborn between January 2009 and December 2013 where attempts were made at resuscitation beyond 10 min.
RESULTS: 87 babies received cardiac massage. 81 babies were live born and 6 were classified as stillborn. Twenty-two babies had no heart rate before 10 min of age. Eight babies survived to 2-year follow-up. 6/11 term babies survived, 2/4 babies born between 32 weeks and 37 weeks survived, and no infants born less than 32 weeks survived (n=7). Of the survivors, 5/8 had a normal neurodevelopmental outcome at 2 years' age. One patient was lost to follow-up, while the other two patients had hemiplegia.
CONCLUSIONS: Our results add to the body of evidence suggesting that having no heart rate before 10 min of age, in term babies, may not be an appropriate prompt to discontinue resuscitation. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

Entities:  

Keywords:  Neonatology; Outcomes research; Resuscitation

Mesh:

Year:  2016        PMID: 27780832     DOI: 10.1136/archdischild-2016-311041

Source DB:  PubMed          Journal:  Arch Dis Child Fetal Neonatal Ed        ISSN: 1359-2998            Impact factor:   5.747


  4 in total

1.  Survival after delivery room cardiopulmonary resuscitation: A national registry study.

Authors:  Elizabeth E Foglia; Erik A Jensen; Myra H Wyckoff; Taylor Sawyer; Alexis Topjian; Sarah J Ratcliffe
Journal:  Resuscitation       Date:  2020-01-23       Impact factor: 5.262

2.  Apgar Scores at 10 Minutes and Outcomes in Term and Late Preterm Neonates with Hypoxic-Ischemic Encephalopathy in the Cooling Era.

Authors:  Marina Ayrapetyan; Kiran Talekar; Kathleen Schwabenbauer; David Carola; Kolawole Solarin; Dorothy McElwee; Susan Adeniyi-Jones; Jay Greenspan; Zubair H Aghai
Journal:  Am J Perinatol       Date:  2018-09-12       Impact factor: 1.862

3.  Timing and documentation of key events in neonatal resuscitation.

Authors:  Adam Charles Heathcote; Jacqueline Jones; Paul Clarke
Journal:  Eur J Pediatr       Date:  2018-04-30       Impact factor: 3.183

Review 4.  Simulation in Neonatal Resuscitation.

Authors:  Aisling A Garvey; Eugene M Dempsey
Journal:  Front Pediatr       Date:  2020-02-25       Impact factor: 3.418

  4 in total

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