AIM: In this prospective multicenter real-life observational cohort study, we investigated the acceptance, adherence and safety of regorafenib, in the treatment of metastatic colorectal cancer patients. PATIENTS & METHODS: A total of 136 patients were recruited at six oncological hospital sites in southern Italy. The adherence to the treatment was measured with patient-completed medication diaries, physician interviews and pill counts. RESULTS: We found a statistically significant improvement of therapy adhesion by the acceptance questionnaire. The Eastern Cooperative Oncology Group performance status, the level of acceptance, the educational level and the concomitant usage of oral medications influenced the adherence to the treatment. CONCLUSION: Patients' level of education, concomitant other oral medications and patients' general clinical condition may influence the adherence to regorafenib.
AIM: In this prospective multicenter real-life observational cohort study, we investigated the acceptance, adherence and safety of regorafenib, in the treatment of metastatic colorectal cancerpatients. PATIENTS & METHODS: A total of 136 patients were recruited at six oncological hospital sites in southern Italy. The adherence to the treatment was measured with patient-completed medication diaries, physician interviews and pill counts. RESULTS: We found a statistically significant improvement of therapy adhesion by the acceptance questionnaire. The Eastern Cooperative Oncology Group performance status, the level of acceptance, the educational level and the concomitant usage of oral medications influenced the adherence to the treatment. CONCLUSION:Patients' level of education, concomitant other oral medications and patients' general clinical condition may influence the adherence to regorafenib.
Authors: Mélanie Dos Santos; M Lange; R Gervais; B Clarisse; A Capel; M Barillet; J M Grellard; N Heutte; I Licaj; F Joly Journal: Support Care Cancer Date: 2019-01-28 Impact factor: 3.603
Authors: Anuj K Patel; Ritika Abhyankar; Lauren K Brais; Mei Sheng Duh; Victoria E Barghout; Lynn Huynh; Mihran A Yenikomshian; Kimmie Ng; Charles S Fuchs Journal: Oncologist Date: 2021-10-01
Authors: Anuj K Patel; Victoria Barghout; Mihran A Yenikomshian; Guillaume Germain; Philippe Jacques; François Laliberté; Mei S Duh Journal: Oncologist Date: 2019-10-07
Authors: Margherita Nannini; Maria Concetta Nigro; Bruno Vincenzi; Elena Fumagalli; Giovanni Grignani; Lorenzo D'Ambrosio; Giuseppe Badalamenti; Lorena Incorvaia; Raffaella Bracci; Silvia Gasperoni; Maristella Saponara; Lidia Gatto; Valentina Indio; Annalisa Astolfi; Valerio Di Scioscio; Paolo G Casali; Giuseppe Tonini; Massimo Aglietta; Antonio Russo; Guido Biasco; Maria A Pantaleo Journal: Ther Adv Med Oncol Date: 2017-12-19 Impact factor: 8.168