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Literature DB >> 27777943

Noncoding RNAs as therapeutics for acetaminophen-induced liver injury.

Benjamin L Woolbright¹, Hartmut Jaeschke¹.

Abstract

Entities: Chemical Disease

Year: 2016 PMID： 27777943 PMCID： PMC5067361 DOI： 10.21037/sci.2016.09.10

Source DB: PubMed Journal: Stem Cell Investig ISSN： 2306-9759

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25 in total

1. Bile acid-induced necrosis in primary human hepatocytes and in patients with obstructive cholestasis.

Authors: Benjamin L Woolbright; Kenneth Dorko; Daniel J Antoine; Joanna I Clarke; Parviz Gholami; Feng Li; Sean C Kumer; Timothy M Schmitt; Jameson Forster; Fang Fan; Rosalind E Jenkins; B Kevin Park; Bruno Hagenbuch; Mojtaba Olyaee; Hartmut Jaeschke
Journal: Toxicol Appl Pharmacol Date: 2015-01-28 Impact factor: 4.219

2. Mechanisms of acetaminophen-induced cell death in primary human hepatocytes.

Authors: Yuchao Xie; Mitchell R McGill; Kenneth Dorko; Sean C Kumer; Timothy M Schmitt; Jameson Forster; Hartmut Jaeschke
Journal: Toxicol Appl Pharmacol Date: 2014-06-03 Impact factor: 4.219

3. miR-122, a mammalian liver-specific microRNA, is processed from hcr mRNA and may downregulate the high affinity cationic amino acid transporter CAT-1.

Authors: Jinhong Chang; Emmanuelle Nicolas; Debora Marks; Chris Sander; Anthony Lerro; Marie Annick Buendia; Chunxiao Xu; William S Mason; Thomas Moloshok; Roque Bort; Kenneth S Zaret; John M Taylor
Journal: RNA Biol Date: 2004-07-01 Impact factor: 4.652

4. Transcriptome association analysis identifies miR-375 as a major determinant of variable acetaminophen glucuronidation by human liver.

Authors: Ioannis Papageorgiou; Marina Freytsis; Michael H Court
Journal: Biochem Pharmacol Date: 2016-08-13 Impact factor: 5.858

Review 5. Pathophysiological significance of c-jun N-terminal kinase in acetaminophen hepatotoxicity.

Authors: Kuo Du; Yuchao Xie; Mitchell R McGill; Hartmut Jaeschke
Journal: Expert Opin Drug Metab Toxicol Date: 2015-07-20 Impact factor: 4.481

6. Single-Nucleotide Polymorphisms in Cytochrome P450 2E1 (CYP2E1) 3'-Untranslated Region Affect the Regulation of CYP2E1 by miR-570.

Authors: Masataka Nakano; Takuya Mohri; Tatsuki Fukami; Masataka Takamiya; Yasuhiro Aoki; Howard L McLeod; Miki Nakajima
Journal: Drug Metab Dispos Date: 2015-07-21 Impact factor: 3.922

Noncoding RNAs as therapeutics for acetaminophen-induced liver injury.

1. Bile acid-induced necrosis in primary human hepatocytes and in patients with obstructive cholestasis.

2. Mechanisms of acetaminophen-induced cell death in primary human hepatocytes.

3. miR-122, a mammalian liver-specific microRNA, is processed from hcr mRNA and may downregulate the high affinity cationic amino acid transporter CAT-1.

4. Transcriptome association analysis identifies miR-375 as a major determinant of variable acetaminophen glucuronidation by human liver.

Review 5. Pathophysiological significance of c-jun N-terminal kinase in acetaminophen hepatotoxicity.

6. Single-Nucleotide Polymorphisms in Cytochrome P450 2E1 (CYP2E1) 3'-Untranslated Region Affect the Regulation of CYP2E1 by miR-570.

7. Circulating microRNA profiles in human patients with acetaminophen hepatotoxicity or ischemic hepatitis.

8. Mitochondrial permeability transition in acetaminophen-induced necrosis and apoptosis of cultured mouse hepatocytes.

9. Novel mechanisms of protection against acetaminophen hepatotoxicity in mice by glutathione and N-acetylcysteine.

10. Reducing Hepatocyte Injury and Necrosis in Response to Paracetamol Using Noncoding RNAs.