Literature DB >> 2777383

Identification of an immunodominant antigenically conserved 32-kilodalton protein from Cowdria ruminantium.

F Jongejan1, M J Thielemans.   

Abstract

Western blotting (immunoblotting) of Cowdria ruminantium antigens with goat or mouse antiserum identified a periodate-resistant, proteinase K-sensitive immunodominant antigen of 32,000 daltons. This protein, designated Cr32, could be demonstrated in goat choroid plexus infected with one of two different Cowdria stocks. Antisera against nine different Cowdria stocks from Africa and the Caribbean region recognized Cr32, which indicates that this protein contains conserved antigenic determinants.

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Year:  1989        PMID： 2777383      PMCID： PMC260799          DOI： 10.1128/iai.57.10.3243-3246.1989

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  17 in total

1.  The influence of certain salts, amino acids, sugars, and proteins on the stability of rickettsiae.

Authors:  M R BOVARNICK; J C MILLER; J C SNYDER
Journal:  J Bacteriol       Date:  1950-04       Impact factor: 3.490

2.  The passage of Cowdria ruminantium in mice.

Authors:  J L du Plessis; N A Kumm
Journal:  J S Afr Vet Med Assoc       Date:  1971-09

3.  Demonstration of colonies of Cowdria ruminantium in midgut epithelial cells of Amblyomma variegatum.

Authors:  K M Kocan; S P Morzaria; W P Voigt; J Kiarie; A D Irvin
Journal:  Am J Vet Res       Date:  1987-03       Impact factor: 1.156

4.  The historical background and global importance of heartwater.

Authors:  A Provost; J D Bezuidenhout
Journal:  Onderstepoort J Vet Res       Date:  1987-09       Impact factor: 1.792

5.  "Western blotting": electrophoretic transfer of proteins from sodium dodecyl sulfate--polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A.

Authors:  W N Burnette
Journal:  Anal Biochem       Date:  1981-04       Impact factor: 3.365

Review 6.  Heartwater (Cowdria ruminantium infection): current status.

Authors:  G Uilenberg
Journal:  Adv Vet Sci Comp Med       Date:  1983

7.  [A strain of Cowdria ruminantium isolated in Guadeloupe (French West Indies)].

Authors:  G Uilenberg; E Camus; N Barré
Journal:  Rev Elev Med Vet Pays Trop       Date:  1985

8.  A method for determining the Cowdria ruminantium infection rate of Amblyomma hebraeum: effects in mice injected with tick homogenates.

Authors:  J L Du Plessis
Journal:  Onderstepoort J Vet Res       Date:  1985-06       Impact factor: 1.792

9.  Isolation and transmission of Cowdria ruminantium (causal agent of heartwater disease) in Blue Nile Province, Sudan.

Authors:  F Jongejan; S P Morzaria; O A Shariff; H M Abdalla
Journal:  Vet Res Commun       Date:  1984-05       Impact factor: 2.459

10.  Experimental transmission of Cowdria ruminantium by the Gulf coast tick Amblyomma maculatum: danger of introducing heartwater and benign African theileriasis onto the American mainland.

Authors:  G Uilenberg
Journal:  Am J Vet Res       Date:  1982-07       Impact factor: 1.156
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  18 in total

Review 1.  Recent advances in determining the pathogenesis of canine monocytic ehrlichiosis.

Authors:  S Harrus; T Waner; H Bark; F Jongejan; A W Cornelissen
Journal:  J Clin Microbiol       Date:  1999-09       Impact factor: 5.948

2.  Monoclonal antibody binding to a surface-exposed epitope on Cowdria ruminantium that is conserved among eight strains.

Authors:  S Shompole; F R Rurangirwa; A Wambugu; J Sitienei; D M Mwangi; A J Musoke; S Mahan; C W Wells; T C McGuire
Journal:  Clin Diagn Lab Immunol       Date:  2000-11

3.  Ehrlichia ruminantium major antigenic protein gene (map1) variants are not geographically constrained and show no evidence of having evolved under positive selection pressure.

Authors:  M T Allsopp; C M Dorfling; J C Maillard; A Bensaid; D T Haydon; H van Heerden; B A Allsopp
Journal:  J Clin Microbiol       Date:  2001-11       Impact factor: 5.948

4.  Identification of Cowdria ruminantium antigens that stimulate proliferation of lymphocytes from cattle immunized by infection and treatment or with inactivated organisms.

Authors:  M Van Kleef; N J Gunter; H Macmillan; B A Allsopp; V Shkap; W C Brown
Journal:  Infect Immun       Date:  2000-02       Impact factor: 3.441

5.  Antibody responses to MAP 1B and other Cowdria ruminantium antigens are down regulated in cattle challenged with tick-transmitted heartwater.

Authors:  S M Semu; T F Peter; D Mukwedeya; A F Barbet; F Jongejan; S M Mahan
Journal:  Clin Diagn Lab Immunol       Date:  2001-03

6.  Size variation of the major immunodominant protein of Cowdria ruminantium.

Authors:  A F Barbet; S M Semu; N Chigagure; P J Kelly; F Jongejan; S M Mahan
Journal:  Clin Diagn Lab Immunol       Date:  1994-11

Review 7.  The tribe Ehrlichieae and ehrlichial diseases.

Authors:  Y Rikihisa
Journal:  Clin Microbiol Rev       Date:  1991-07       Impact factor: 26.132

8.  Development of a polyclonal competitive enzyme-linked immunosorbent assay for detection of antibodies to Ehrlichia ruminantium.

Authors:  Keith J Sumption; Edith A Paxton; Lesley Bell-Sakyi
Journal:  Clin Diagn Lab Immunol       Date:  2003-09

9.  An immunoblotting diagnostic assay for heartwater based on the immunodominant 32-kilodalton protein of Cowdria ruminantium detects false positives in field sera.

Authors:  S M Mahan; N Tebele; D Mukwedeya; S Semu; C B Nyathi; L A Wassink; P J Kelly; T Peter; A F Barbet
Journal:  J Clin Microbiol       Date:  1993-10       Impact factor: 5.948

10.  Protective immunity to heartwater (Cowdria ruminantium infection) is acquired after vaccination with in vitro-attenuated rickettsiae.

Authors:  F Jongejan
Journal:  Infect Immun       Date:  1991-02       Impact factor: 3.441
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